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- W1917800718 endingPage "94" @default.
- W1917800718 startingPage "51" @default.
- W1917800718 abstract "This chapter reviews the evidence in favor of the concept that B cells can serve as antigen-presenting accessory cells to T cells of the helper/inducer subset as well as the experiments suggesting that this is a critical step in the differentiation of B cells for a T-dependent immune response. The unique characteristic of B cell antigen-presenting capacity lies in the ability of specific B cells to efficiently take up antigen via their immunoglobulin receptors and to present those antigen to antigen-specific helper T cells. Although this proposed mechanism of antigen presentation to T cells by B cells explains many features of T–B interactions, such as the major histocompatibility complex (MHC) restriction and the requirement for hapten and carrier to be on the same macromolecule to facilitate efficient T–B interaction, the relevancy of this mechanism for an in vivo immune response remains to be demonstrated." @default.
- W1917800718 created "2016-06-24" @default.
- W1917800718 creator A5026083514 @default.
- W1917800718 creator A5062001150 @default.
- W1917800718 date "1986-01-01" @default.
- W1917800718 modified "2023-10-16" @default.
- W1917800718 title "Antigen Presentation by B Cells and Its Significance in T-B Interactions" @default.
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- W1917800718 doi "https://doi.org/10.1016/s0065-2776(08)60348-x" @default.
- W1917800718 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3538822" @default.
- W1917800718 hasPublicationYear "1986" @default.