Matches in SemOpenAlex for { <https://semopenalex.org/work/W1918301869> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W1918301869 startingPage "943" @default.
- W1918301869 abstract "Introduction Parenteral prostanoids are considered to be the most potent agents in the treatment of pulmonary arterial hypertension (PAH). However, administration of prostanoids with external pump systems is technically challenging and associated with side effects such as infusion site pain with subcutaneous (s.c.) and possibly life-threatening catheter-related infections with intravenous (i.v.) administration. The Lenus Pro implantable infusion pump was specifically developed to overcome the drawbacks of s.c. administration. In 2010, we reported the first implantation of a Lenus Pro pump with a filling interval of 28 days. Results Between September 2010 and October 2011, 14 patients underwent implantation at our center. All patients had previously shown significant clinical response to s.c. Treprostinil but suffered from site pain. Implantations were performed under general anesthesia. After preparation of the pump pocket in the abdominal wall the pump was connected to the central venous access. No intraoperative complications occurred. Postoperatively two patients developed a mild seroma. No other complications especially no infections were observed. Up to now more than 100 refill procedures were performed. Conclusions This first pilot study demonstrates that i.v. Treprostinil, delivered by the implantable pump Lenus Pro® is safe, effective and feasible in PAH patients transitioned from s.c. Treprostinil. Filling intervals of 28 days ensure optimal compliance and long-term patient management. The absence of side effects such as infusion site pain is associated with a dramatic increase in quality of life." @default.
- W1918301869 created "2016-06-24" @default.
- W1918301869 creator A5009811973 @default.
- W1918301869 creator A5019774248 @default.
- W1918301869 creator A5038179950 @default.
- W1918301869 creator A5040589263 @default.
- W1918301869 creator A5051326153 @default.
- W1918301869 creator A5051486712 @default.
- W1918301869 creator A5074817779 @default.
- W1918301869 date "2012-09-01" @default.
- W1918301869 modified "2023-09-26" @default.
- W1918301869 title "First long-term experience with intravenous treprostinil administered by the implantable infusion pump LenusPro. A single-center pilot study" @default.
- W1918301869 hasPublicationYear "2012" @default.
- W1918301869 type Work @default.
- W1918301869 sameAs 1918301869 @default.
- W1918301869 citedByCount "0" @default.
- W1918301869 crossrefType "journal-article" @default.
- W1918301869 hasAuthorship W1918301869A5009811973 @default.
- W1918301869 hasAuthorship W1918301869A5019774248 @default.
- W1918301869 hasAuthorship W1918301869A5038179950 @default.
- W1918301869 hasAuthorship W1918301869A5040589263 @default.
- W1918301869 hasAuthorship W1918301869A5051326153 @default.
- W1918301869 hasAuthorship W1918301869A5051486712 @default.
- W1918301869 hasAuthorship W1918301869A5074817779 @default.
- W1918301869 hasConcept C126322002 @default.
- W1918301869 hasConcept C141071460 @default.
- W1918301869 hasConcept C2776187130 @default.
- W1918301869 hasConcept C2776432619 @default.
- W1918301869 hasConcept C2780930700 @default.
- W1918301869 hasConcept C2781267111 @default.
- W1918301869 hasConcept C42219234 @default.
- W1918301869 hasConcept C71924100 @default.
- W1918301869 hasConceptScore W1918301869C126322002 @default.
- W1918301869 hasConceptScore W1918301869C141071460 @default.
- W1918301869 hasConceptScore W1918301869C2776187130 @default.
- W1918301869 hasConceptScore W1918301869C2776432619 @default.
- W1918301869 hasConceptScore W1918301869C2780930700 @default.
- W1918301869 hasConceptScore W1918301869C2781267111 @default.
- W1918301869 hasConceptScore W1918301869C42219234 @default.
- W1918301869 hasConceptScore W1918301869C71924100 @default.
- W1918301869 hasLocation W19183018691 @default.
- W1918301869 hasOpenAccess W1918301869 @default.
- W1918301869 hasPrimaryLocation W19183018691 @default.
- W1918301869 hasRelatedWork W1973524023 @default.
- W1918301869 hasRelatedWork W2040839530 @default.
- W1918301869 hasRelatedWork W2042888645 @default.
- W1918301869 hasRelatedWork W2204851177 @default.
- W1918301869 hasRelatedWork W2235524605 @default.
- W1918301869 hasRelatedWork W2402456276 @default.
- W1918301869 hasRelatedWork W2419659222 @default.
- W1918301869 hasRelatedWork W2425965730 @default.
- W1918301869 hasRelatedWork W2485658572 @default.
- W1918301869 hasRelatedWork W2606852271 @default.
- W1918301869 hasRelatedWork W2610467506 @default.
- W1918301869 hasRelatedWork W2622216185 @default.
- W1918301869 hasRelatedWork W2772562901 @default.
- W1918301869 hasRelatedWork W2776775103 @default.
- W1918301869 hasRelatedWork W2810885319 @default.
- W1918301869 hasRelatedWork W3009358503 @default.
- W1918301869 hasRelatedWork W3093549955 @default.
- W1918301869 hasRelatedWork W37454214 @default.
- W1918301869 hasRelatedWork W1981735761 @default.
- W1918301869 hasRelatedWork W2183099262 @default.
- W1918301869 hasVolume "40" @default.
- W1918301869 isParatext "false" @default.
- W1918301869 isRetracted "false" @default.
- W1918301869 magId "1918301869" @default.
- W1918301869 workType "article" @default.