Matches in SemOpenAlex for { <https://semopenalex.org/work/W1918537068> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W1918537068 endingPage "1307" @default.
- W1918537068 startingPage "1297" @default.
- W1918537068 abstract "Abstract Both natural selection and mutational biases contribute to variation in codon usage bias within Drosophila species. This study addresses the cause of codon bias differences between the sibling species, Drosophila melanogaster and D. simulans. Under a model of mutation-selection-drift, variation in mutational processes between species predicts greater base composition differences in neutrally evolving regions than in highly biased genes. Variation in selection intensity, however, predicts larger base composition differences in highly biased loci. Greater differences in the G+C content of 34 coding regions than 46 intron sequences between D. melanogaster and D. simulans suggest that D. melanogaster has undergone a reduction in selection intensity for codon bias. Computer simulations suggest at least a fivefold reduction in Nes at silent sites in this lineage. Other classes of molecular change show lineage effects between these species. Rates of amino acid substitution are higher in the D. melanogaster lineage than in D. simulans in 14 genes for which outgroup sequences are available. Surprisingly, protein sizes are larger in D. melanogaster than in D. simulans in the 34 genes compared between the two species. A substantial fraction of silent, replacement, and insertion/deletion mutations in coding regions may be weakly selected in Drosophila." @default.
- W1918537068 created "2016-06-24" @default.
- W1918537068 creator A5064704825 @default.
- W1918537068 date "1996-11-01" @default.
- W1918537068 modified "2023-10-08" @default.
- W1918537068 title "Molecular Evolution Between <i>Drosophila melanogaster</i> and <i>D. simulans</i> Reduced Codon Bias, Faster Rates of Amino Acid Substitution, and Larger Proteins in <i>D. melanogaster</i>" @default.
- W1918537068 doi "https://doi.org/10.1093/genetics/144.3.1297" @default.
- W1918537068 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1207620" @default.
- W1918537068 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8913769" @default.
- W1918537068 hasPublicationYear "1996" @default.
- W1918537068 type Work @default.
- W1918537068 sameAs 1918537068 @default.
- W1918537068 citedByCount "197" @default.
- W1918537068 countsByYear W19185370682012 @default.
- W1918537068 countsByYear W19185370682013 @default.
- W1918537068 countsByYear W19185370682014 @default.
- W1918537068 countsByYear W19185370682015 @default.
- W1918537068 countsByYear W19185370682016 @default.
- W1918537068 countsByYear W19185370682017 @default.
- W1918537068 countsByYear W19185370682018 @default.
- W1918537068 countsByYear W19185370682019 @default.
- W1918537068 countsByYear W19185370682020 @default.
- W1918537068 countsByYear W19185370682023 @default.
- W1918537068 crossrefType "journal-article" @default.
- W1918537068 hasAuthorship W1918537068A5064704825 @default.
- W1918537068 hasBestOaLocation W19185370682 @default.
- W1918537068 hasConcept C104317684 @default.
- W1918537068 hasConcept C141231307 @default.
- W1918537068 hasConcept C154945302 @default.
- W1918537068 hasConcept C166393388 @default.
- W1918537068 hasConcept C2776817793 @default.
- W1918537068 hasConcept C2776998849 @default.
- W1918537068 hasConcept C2780104201 @default.
- W1918537068 hasConcept C41008148 @default.
- W1918537068 hasConcept C54355233 @default.
- W1918537068 hasConcept C7386963 @default.
- W1918537068 hasConcept C75268714 @default.
- W1918537068 hasConcept C78458016 @default.
- W1918537068 hasConcept C81917197 @default.
- W1918537068 hasConcept C86803240 @default.
- W1918537068 hasConcept C87253356 @default.
- W1918537068 hasConcept C90132467 @default.
- W1918537068 hasConceptScore W1918537068C104317684 @default.
- W1918537068 hasConceptScore W1918537068C141231307 @default.
- W1918537068 hasConceptScore W1918537068C154945302 @default.
- W1918537068 hasConceptScore W1918537068C166393388 @default.
- W1918537068 hasConceptScore W1918537068C2776817793 @default.
- W1918537068 hasConceptScore W1918537068C2776998849 @default.
- W1918537068 hasConceptScore W1918537068C2780104201 @default.
- W1918537068 hasConceptScore W1918537068C41008148 @default.
- W1918537068 hasConceptScore W1918537068C54355233 @default.
- W1918537068 hasConceptScore W1918537068C7386963 @default.
- W1918537068 hasConceptScore W1918537068C75268714 @default.
- W1918537068 hasConceptScore W1918537068C78458016 @default.
- W1918537068 hasConceptScore W1918537068C81917197 @default.
- W1918537068 hasConceptScore W1918537068C86803240 @default.
- W1918537068 hasConceptScore W1918537068C87253356 @default.
- W1918537068 hasConceptScore W1918537068C90132467 @default.
- W1918537068 hasIssue "3" @default.
- W1918537068 hasLocation W19185370681 @default.
- W1918537068 hasLocation W19185370682 @default.
- W1918537068 hasLocation W19185370683 @default.
- W1918537068 hasOpenAccess W1918537068 @default.
- W1918537068 hasPrimaryLocation W19185370681 @default.
- W1918537068 hasRelatedWork W2036483423 @default.
- W1918537068 hasRelatedWork W2071537172 @default.
- W1918537068 hasRelatedWork W2095627741 @default.
- W1918537068 hasRelatedWork W2118872527 @default.
- W1918537068 hasRelatedWork W2163262396 @default.
- W1918537068 hasRelatedWork W2408830493 @default.
- W1918537068 hasRelatedWork W2751446000 @default.
- W1918537068 hasRelatedWork W2758898883 @default.
- W1918537068 hasRelatedWork W3097080146 @default.
- W1918537068 hasRelatedWork W4211107165 @default.
- W1918537068 hasVolume "144" @default.
- W1918537068 isParatext "false" @default.
- W1918537068 isRetracted "false" @default.
- W1918537068 magId "1918537068" @default.
- W1918537068 workType "article" @default.