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- W1918596645 abstract "To determine risk factors during neonatal hospital stay and follow‐up associated with failure to thrive in the first year of life of very low birth weight newborns.Study of preterm very low birth weight newborns followed from 2006 to 2013 in a public institutional hospital program. The study included newborns that attended at least one appointment in each of the three periods: Period I, up to 3 months of corrected age (CA); Period II, 4–6 months of CA; and Period III, 7–12 months of CA. The variables were analyzed by logistic regression with XLSTAT 2014 software (Microsoft®, WA, USA). Failure to thrive (Z‐score below −2 SD) was classified as a dichotomous dependent variable (0 – failure/1 – success), while the other variables were classified as explanatory variables for the hospitalization periods and for each of the follow‐up periods (I, II, and III).Children born adequate for gestational age increased the chance of Z‐score for weight at discharge > −2 SD (OR = 10.217; 95% CI: 1.117–93.436). Metabolic bone disease and retinopathy of prematurity in Period I, as well as hospital readmissions in Periods II and III during follow‐up increased the chance of Z‐score < −2 SD.Failure to thrive is influenced by intrauterine factors and, subsequently, by several morbidities, both in the birth and hospitalization period, as well as in the post‐discharge period and thus, such variables should be prioritized in the follow‐up.Determinar fatores de risco do período de internação neonatal e do seguimento ambulatorial associados à falha de crescimento no primeiro ano de vida de recém‐nascidos de muito baixo peso.Estudo com crianças nascidas prematuras de muito baixo peso em acompanhamento de 2006 a 2013 em ambulatório de alto risco de um hospital‐escola. Incluídas aquelas que fizera pelo menos uma consulta em cada um dos três períodos assim determinados: Período I – até três meses de idade corrigida (IC); Período II – entre quatro e seis meses de IC; e Período III – entre sete e 12 meses de IC. As variáveis foram analisadas por regressão logística com o programa XLStat 2014 (Microsoft®, WA, EUA). A falha de crescimento (escore z abaixo de ‐−2 DP) foi classificada como variável dependente do tipo dicotômica (0 – falha/1 – sucesso) e as demais variáveis foram classificadas como variáveis explicativas para os períodos de internação e para cada um dos períodos de seguimento (I, II e III).Nascer adequado para a idade gestacional aumenta a chance de apresentar escore Z do peso na alta hospitalar acima de −2 DP (OR = 10,217; IC95% 1.117‐93,436). Doença metabólica óssea e retinopatia da prematuridade durante o Período I e reinternações nos Períodos II e III de seguimento aumentam a chance de escore z abaixo de −2 DP.A falha de crescimento é influenciada por fatores intrauterinos e posteriormente por diversas morbidades, tanto no período da internação como no pós‐alta. Tais variáveis estudadas deveriam ter prioridade no seguimento." @default.
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- W1918596645 date "2015-09-01" @default.
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- W1918596645 title "Evaluation of the Iam CMV Q-LAMP Quantitative assay for detecting and quantifying CMD-DNA in plasma samples" @default.
- W1918596645 doi "https://doi.org/10.1016/j.jcv.2015.07.193" @default.
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