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- W1918856919 abstract "To test the hypothesis that MRI can monitor intraportal vein (IPV) transcatheter delivery of clinically applicable heparin-protamine-ferumoxytol (HPF) nanocomplex-labeled natural killer (NK) cells to liver tumor.Liver tumor rat models underwent catheterization for IPV infusion of HPF-labeled NK cells (NK-92MI cell line). MRI measurements within tumor and adjacent liver tissues were compared pre- and post-NK cell infusion. Histology studies were used to identify NK cells in the target tumors.For first time, we demonstrated that MRI tracks HPF-labeled NK cells migration within liver following IPV delivery.IPV transcatheter infusion permitted selective delivery of NK cells to liver tissues and MRI allowed tracking NK cell biodistributions within the tumors." @default.
- W1918856919 created "2016-06-24" @default.
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- W1918856919 date "2015-06-01" @default.
- W1918856919 modified "2023-09-27" @default.
- W1918856919 title "Clinically applicable magnetic-labeling of natural killer cells for MRI of transcatheter delivery to liver tumors: preclinical validation for clinical translation" @default.
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- W1918856919 doi "https://doi.org/10.2217/nnm.15.24" @default.
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