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- W191920402 abstract "Major features of bronchial asthma include bronchial hyperresponsiveness and airway inflammation and a number of mechanisms have been put forward to explain these phenomena. In this respect, there is considerable evidence that neuronal mechanisms are involved in the pathophysiology of asthma. The contribution of lung sensory nerves to vagally-mediated airway reflexes such as cough and bronchoconstriction is well established. Asthmatics cough and bronchoconstrict to a variety of inhaled irritants such as bradykinin, sulphur dioxide and distilled water which are all known to activate airway sensory neurones in animal studies. Indeed, there is a complex interplay between inflammatory and neuronal control of the airways. Inflammatory mediators affect neurotransmission and neurotransmitters subsequently affect the inflammatory response within the airways." @default.
- W191920402 created "2016-06-24" @default.
- W191920402 creator A5022866786 @default.
- W191920402 date "1999-01-01" @default.
- W191920402 modified "2023-09-23" @default.
- W191920402 title "The relationship between hyperalgesia and hyperresponsiveness in the lung" @default.
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- W191920402 doi "https://doi.org/10.1007/978-3-0348-8753-3_10" @default.
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