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- W1919750296 abstract "Hydrogel scaffolds are used in tissue engineering as a delivery vehicle for regenerative growth factors. Spatiotemporal patterns of growth factor signaling are critical for tissue regeneration, yet most scaffolds afford limited control of growth factor release, especially after implantation. We previously found that acoustic droplet vaporization can control growth factor release from a fibrin scaffold doped with a perfluorocarbon emulsion. This study investigates properties of the acoustically responsive scaffold (ARS) critical for further translation. At 2.5 MHz, acoustic droplet vaporization and inertial cavitation thresholds ranged from 1.5 to 3.0 MPa and from 2.0 to 7.0 MPa peak rarefactional pressure, respectively, for ARSs of varying composition. Viability of C3H/10T1/2 cells, encapsulated in the ARS, did not decrease significantly for pressures below 4 MPa. ARSs with perfluorohexane emulsions displayed higher stability versus those with perfluoropentane emulsions, while surrogate payload release was minimal without ultrasound. These results enable the selection of ARS compositions and acoustic parameters needed for optimized spatiotemporally controlled release." @default.
- W1919750296 created "2016-06-24" @default.
- W1919750296 creator A5022985471 @default.
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- W1919750296 date "2016-01-01" @default.
- W1919750296 modified "2023-09-23" @default.
- W1919750296 title "Design and Characterization of Fibrin-Based Acoustically Responsive Scaffolds for Tissue Engineering Applications" @default.
- W1919750296 cites W191624211 @default.
- W1919750296 cites W1963904718 @default.
- W1919750296 cites W1964846552 @default.
- W1919750296 cites W1967776587 @default.
- W1919750296 cites W1970294584 @default.
- W1919750296 cites W1970935015 @default.
- W1919750296 cites W1971037061 @default.
- W1919750296 cites W1972436866 @default.
- W1919750296 cites W1972448673 @default.
- W1919750296 cites W1976921755 @default.
- W1919750296 cites W1980334226 @default.
- W1919750296 cites W1982387849 @default.
- W1919750296 cites W1988937463 @default.
- W1919750296 cites W1995475798 @default.
- W1919750296 cites W1995873025 @default.
- W1919750296 cites W1998220101 @default.
- W1919750296 cites W2001455415 @default.
- W1919750296 cites W2002769519 @default.
- W1919750296 cites W2003541627 @default.
- W1919750296 cites W2004539235 @default.
- W1919750296 cites W2007457253 @default.
- W1919750296 cites W2009314066 @default.
- W1919750296 cites W2017002860 @default.
- W1919750296 cites W2022961329 @default.
- W1919750296 cites W2023939425 @default.
- W1919750296 cites W2039439383 @default.
- W1919750296 cites W2042574165 @default.
- W1919750296 cites W2043902038 @default.
- W1919750296 cites W2045556067 @default.
- W1919750296 cites W2046127741 @default.
- W1919750296 cites W2047849605 @default.
- W1919750296 cites W2053564836 @default.
- W1919750296 cites W2053953203 @default.
- W1919750296 cites W2054400934 @default.
- W1919750296 cites W2057062683 @default.
- W1919750296 cites W2057131748 @default.
- W1919750296 cites W2057442273 @default.
- W1919750296 cites W2061501935 @default.
- W1919750296 cites W2064813253 @default.
- W1919750296 cites W2067747619 @default.
- W1919750296 cites W2076728050 @default.
- W1919750296 cites W2080092639 @default.
- W1919750296 cites W2080847320 @default.
- W1919750296 cites W2081081726 @default.
- W1919750296 cites W2081223913 @default.
- W1919750296 cites W2081563515 @default.
- W1919750296 cites W2083973152 @default.
- W1919750296 cites W2084829967 @default.
- W1919750296 cites W2085932421 @default.
- W1919750296 cites W2087494159 @default.
- W1919750296 cites W2094097178 @default.
- W1919750296 cites W2099639306 @default.
- W1919750296 cites W2100209466 @default.
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- W1919750296 cites W2116212113 @default.
- W1919750296 cites W2116351792 @default.
- W1919750296 cites W2117558556 @default.
- W1919750296 cites W2119397071 @default.
- W1919750296 cites W2120833207 @default.
- W1919750296 cites W2129431680 @default.
- W1919750296 cites W2133557431 @default.
- W1919750296 cites W2135603848 @default.
- W1919750296 cites W2138071386 @default.
- W1919750296 cites W2156766018 @default.
- W1919750296 cites W2161074350 @default.
- W1919750296 cites W2165991438 @default.
- W1919750296 cites W2167623882 @default.
- W1919750296 cites W2411323646 @default.
- W1919750296 cites W4231516524 @default.
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- W1919750296 doi "https://doi.org/10.1016/j.ultrasmedbio.2015.08.018" @default.
- W1919750296 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4666743" @default.
- W1919750296 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26526782" @default.
- W1919750296 hasPublicationYear "2016" @default.
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