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• W1920007059 abstract "XenotransplantationVolume 22, Issue 5 p. 406-407 Letter to the Editor Characterization of the cellular infiltrate in bioprosthetic heart valves explanted from patients with structural valve deterioration Rizwan A. Manji, Rizwan A. Manji [email protected] Department of Surgery, University of Manitoba, Winnipeg, MB, Canada Cardiac Sciences Program, Winnipeg Regional Health Authority and St Boniface Hospital, Winnipeg, MB, CanadaSearch for more papers by this authorHidetaka Hara, Hidetaka Hara Thomas E. Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA, USASearch for more papers by this authorDavid K. C. Cooper, David K. C. Cooper Thomas E. Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA, USASearch for more papers by this author Rizwan A. Manji, Rizwan A. Manji [email protected] Department of Surgery, University of Manitoba, Winnipeg, MB, Canada Cardiac Sciences Program, Winnipeg Regional Health Authority and St Boniface Hospital, Winnipeg, MB, CanadaSearch for more papers by this authorHidetaka Hara, Hidetaka Hara Thomas E. Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA, USASearch for more papers by this authorDavid K. C. Cooper, David K. C. Cooper Thomas E. Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA, USASearch for more papers by this author First published: 27 August 2015 https://doi.org/10.1111/xen.12187Citations: 13Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat No abstract is available for this article. References 1Manji RA, Menkis AH, Ekser B, Cooper DKC. Bioprosthetic heart valves of the future. Xenotransplantation 2014; 21: 1–10. 2Park CS, Park SS, Choi SY et al. Anti alpha-gal immune response following porcine bioprosthesis implantation in children. J Heart Valve Dis 2010; 19: 124–130. 3Naso F, Gandaglia A, Bottio T et al. First quantification of alpha-Gal epitope in current glutaraldehyde-fixed heart valve bioprostheses. Xenotransplantation 2013; 20: 252–261. 4Konakci KZ, Bohle B, Blumer R et al. Alpha-Gal on bioprostheses: xenograft immune response in cardiac surgery. Eur J Clin Invest 2005; 35: 17–23. 5Lee W, Hara H, Cooper DK, Manji RA. Expression of NeuGc on pig heart valves. Xenotransplantation 2015; 22: 153–154. 6Jin R, Greenwald A, Peterson MD, Waddell TK. Human monocytes recognize porcine endothelium via the interaction of galectin 3 and alpha-GAL. J Immunol 2006; 177: 1289–1295. 7Cho HJ, Kim HS. Osteopontin: a multifunctional protein at the crossroads of inflammation, atherosclerosis, and vascular calcification. Curr Atheroscler Rep 2009; 11: 206–213. 8Scatena M, Liaw L, Giachelli CM. Osteopontin: a multifunctional molecule regulating chronic inflammation and vascular disease. Arterioscler Thromb Vasc Biol 2007; 27: 2302–2309. 9Manji RA, Zhu LF, Nijjar NK et al. Glutaraldehyde-fixed bioprosthetic heart valve conduits calcify and fail from xenograft rejection. Circulation 2006; 114: 318–327. 10Good AH, Cooper DK, Malcolm AJ et al. Identification of carbohydrate structures that bind human antiporcine antibodies: implications for discordant xenografting in humans. Transplant Proc 1992; 24: 559–562. 11Phelps CJ, Koike C, Vaught TD et al. Production of alpha 1,3-galactosyltransferase-deficient pigs. Science 2003; 299: 411–414. 12Bouhours D, Pourcel C, Bouhours JE. Simultaneous expression by porcine aorta endothelial cells of glycosphingolipids bearing the major epitope for human xenoreactive antibodies (Gal alpha 1-3Gal), blood group H determinant and N-glycolylneuraminic acid. Glycoconj J 1996; 13: 947–953. 13Lutz AJ, Li P, Estrada JL, Sidner RA et al. Double knockout pigs deficient in N-glycolylneuraminic acid and galactose alpha-1,3-galactose reduce the humoral barrier to xenotransplantation. Xenotransplantation 2013; 20: 27–35. 14Byrne GW, Du Z, Stalboerger P, Kogelberg H, McGregor CG. Cloning and expression of porcine beta1,4 N-acetylgalactosaminyl transferase encoding a new xenoreactive antigen. Xenotransplantation 2014; 21: 543–554. 15Estrada JL, Martens G, Li P et al. Evaluation of human and non-human primate antibody binding to pig cells lacking GGTA1/CMAH/beta4GalNT2 genes. Xenotransplantation 2015; 22: 194–202. 16Wilhite T, Ezzelarab C, Hara H et al. The effect of Gal expression on pig cells on the human T-cell xenoresponse. Xenotransplantation 2012; 19: 56–63. 17Yang YG. CD47 in xenograft rejection and tolerance induction. Xenotransplantation 2010; 17: 267–273. 18Tena A, Kurtz J, Leonard DA et al. Transgenic expression of human CD47 markedly increases engraftment in a murine model of pig-to-human hematopoietic cell transplantation. Am J Transplant 2014; 14: 2713–2722. Citing Literature Volume22, Issue5September/October 2015Pages 406-407 ReferencesRelatedInformation" @default.
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