FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1921124690> ?p ?o ?g. }

• W1921124690 endingPage "171" @default.
• W1921124690 startingPage "163" @default.
• W1921124690 abstract "The CHOP regimen consisting of cyclophosphamide, doxorubicin (DOX), vincristine and prednisolone has been the most used regimen for peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS). Pirarubicin [tetrahydropyranyladriamycin (THP)], a derivative of DOX, is an anthracycline with reportedly less cardiotoxicity than DOX. Here, we confirmed the efficacy of THP-COP using THP instead of DOX in the treatment of PTCL-NOS. The study protocol employed a retrospective, consecutive entry design. We retrospectively analysed 56 patients with PTCL-NOS who had received THP-COP or CHOP. These regimens were performed every 21 days. Twenty-nine patients received THP-COP, and 27 received CHOP. There were no significant differences in known prognostic factors, including in the International Prognostic Index (IPI) and the prognostic index for T-cell lymphoma (PIT), between the two groups. Complete remission rates in patients with THP-COP and CHOP were 52% in both groups; the 3-year overall survival (OS) rates were 67% and 52% (p = 0.074), and the 3-year progression-free survival (PFS) rates were 51% and 29% (p = 0.070), respectively. In patients with low IPI (low or low-intermediate), THP-COP had significantly better 3-year OS (100% vs. 64%; p < 0.001) and 3-year PFS (75% vs. 33%; p < 0.05) than CHOP. Similar differences between THP-COP and CHOP were observed in patients with a low PIT (groups 1 or 2). Our study showed that THP-COP produced results equivalent to CHOP regarding efficacy and safety in patients with PTCL-NOS. In patients with low IPI or PIT, THP-COP resulted in significantly better prognosis. Copyright © 2015 John Wiley & Sons, Ltd." @default.
• W1921124690 created "2016-06-24" @default.
• W1921124690 creator A5002271734 @default.
• W1921124690 creator A5005286789 @default.
• W1921124690 creator A5013764737 @default.
• W1921124690 creator A5016196067 @default.
• W1921124690 creator A5026960957 @default.
• W1921124690 creator A5030753838 @default.
• W1921124690 creator A5030791716 @default.
• W1921124690 creator A5031573518 @default.
• W1921124690 creator A5039176890 @default.
• W1921124690 creator A5047012096 @default.
• W1921124690 creator A5050302856 @default.
• W1921124690 creator A5062668386 @default.
• W1921124690 creator A5065534862 @default.
• W1921124690 creator A5077313439 @default.
• W1921124690 creator A5079776261 @default.
• W1921124690 creator A5085571910 @default.
• W1921124690 creator A5087997167 @default.
• W1921124690 creator A5090297441 @default.
• W1921124690 creator A5090578339 @default.
• W1921124690 date "2015-10-09" @default.
• W1921124690 modified "2023-10-13" @default.
• W1921124690 title "CHOP or THP-COP regimens in the treatment of newly diagnosed peripheral T-cell lymphoma, not otherwise specified: a comparison of doxorubicin and pirarubicin" @default.
• W1921124690 cites W1524390400 @default.
• W1921124690 cites W1819949687 @default.
• W1921124690 cites W1912693401 @default.
• W1921124690 cites W1933265282 @default.
• W1921124690 cites W1966255834 @default.
• W1921124690 cites W1976943426 @default.
• W1921124690 cites W1990670396 @default.
• W1921124690 cites W1998124660 @default.
• W1921124690 cites W1999637438 @default.
• W1921124690 cites W2005136056 @default.
• W1921124690 cites W2009086636 @default.
• W1921124690 cites W2012291988 @default.
• W1921124690 cites W2014980871 @default.
• W1921124690 cites W2015684600 @default.
• W1921124690 cites W2029854218 @default.
• W1921124690 cites W2037284485 @default.
• W1921124690 cites W2042350838 @default.
• W1921124690 cites W2057290270 @default.
• W1921124690 cites W2057897174 @default.
• W1921124690 cites W2058767673 @default.
• W1921124690 cites W2060499380 @default.
• W1921124690 cites W2060620762 @default.
• W1921124690 cites W2095461916 @default.
• W1921124690 cites W2097787459 @default.
• W1921124690 cites W2098666639 @default.
• W1921124690 cites W2108465006 @default.
• W1921124690 cites W2110134677 @default.
• W1921124690 cites W2133267160 @default.
• W1921124690 cites W2134210438 @default.
• W1921124690 cites W2137573211 @default.
• W1921124690 cites W2137905169 @default.
• W1921124690 cites W2138498369 @default.
• W1921124690 cites W2143450001 @default.
• W1921124690 cites W2144933582 @default.
• W1921124690 cites W2148781593 @default.
• W1921124690 cites W2159285007 @default.
• W1921124690 cites W2162389158 @default.
• W1921124690 cites W2166987528 @default.
• W1921124690 cites W2171779983 @default.
• W1921124690 cites W2416844197 @default.
• W1921124690 cites W4205736005 @default.
• W1921124690 doi "https://doi.org/10.1002/hon.2262" @default.
• W1921124690 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26449182" @default.
• W1921124690 hasPublicationYear "2015" @default.
• W1921124690 type Work @default.
• W1921124690 sameAs 1921124690 @default.
• W1921124690 citedByCount "6" @default.
• W1921124690 countsByYear W19211246902016 @default.
• W1921124690 countsByYear W19211246902019 @default.
• W1921124690 countsByYear W19211246902020 @default.
• W1921124690 countsByYear W19211246902021 @default.
• W1921124690 countsByYear W19211246902022 @default.
• W1921124690 crossrefType "journal-article" @default.
• W1921124690 hasAuthorship W1921124690A5002271734 @default.
• W1921124690 hasAuthorship W1921124690A5005286789 @default.
• W1921124690 hasAuthorship W1921124690A5013764737 @default.
• W1921124690 hasAuthorship W1921124690A5016196067 @default.
• W1921124690 hasAuthorship W1921124690A5026960957 @default.
• W1921124690 hasAuthorship W1921124690A5030753838 @default.
• W1921124690 hasAuthorship W1921124690A5030791716 @default.
• W1921124690 hasAuthorship W1921124690A5031573518 @default.
• W1921124690 hasAuthorship W1921124690A5039176890 @default.
• W1921124690 hasAuthorship W1921124690A5047012096 @default.
• W1921124690 hasAuthorship W1921124690A5050302856 @default.
• W1921124690 hasAuthorship W1921124690A5062668386 @default.
• W1921124690 hasAuthorship W1921124690A5065534862 @default.
• W1921124690 hasAuthorship W1921124690A5077313439 @default.
• W1921124690 hasAuthorship W1921124690A5079776261 @default.
• W1921124690 hasAuthorship W1921124690A5085571910 @default.
• W1921124690 hasAuthorship W1921124690A5087997167 @default.
• W1921124690 hasAuthorship W1921124690A5090297441 @default.
• W1921124690 hasAuthorship W1921124690A5090578339 @default.
• W1921124690 hasConcept C121608353 @default.
• W1921124690 hasConcept C126322002 @default.

• next