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• W1921294920 abstract "Le Thanh, B. V., Lessard, M., Chorfi, Y. and Guay, F. 2015. Short Communication: Antioxidant capacity in the intestinal mucosa of weanling piglets fed diets containing Fusarium mycotoxins and the efficacy of commercial supplements sold as detoxifiers. Can. J. Anim. Sci. 95: 569–575. The ability of commercial feed additives to prevent oxidative damage due to deoxynivalenol (DON) in piglets was studied. Sixty piglets (6.0±0.5 kg) were assigned randomly to six wheat–corn–soybean diets: control (<0.5 mg kg −1 DON), DON-rich diet (4 mg kg −1 DON), and four DON-rich diets supplemented with either glucomannan (DON+GLUC), yeast, live bacteria, enzymes and plant extract (DON+YBP), aluminosilicate (DON+ALS), or a mixture of preservatives (DON+PV). Malondialdehyde concentration (MDA), glutathione peroxidase activity (GPx), catalase activity (CAT) and superoxide dismutase activity (SOD) in the small intestine were measured after 14 d. The DON-rich diet increased MDA in the jejunum while decreasing CAT in the jejunum and SOD in the ileum and increasing GPx in the ileum (P<0.05). The DON+GLUC diet decreased GPx and SOD (P<0.05) and tended to decrease MDA in the jejunum (P<0.10). The DON+YBP, DON+PV and DON+ALS diets all decreased CAT in the jejunum, while DON+YBP and DON+PV also did so in the ileum (P<0.05). DON+GLUC decreased SOD in the jejunum, while DON+YBP increased it (P<0.05). In the ileum, DON+PV decreased SOD, while DON+ALS increased GPx (P<0.05). No significant differences in total antioxidant capacity (TAC) in intestinal tissues were found. This study demonstrates that the mycotoxin DON and anti-mycotoxin additives modify oxidative status, including the antioxidant enzyme activities (CAT, SOD or GPx) in the intestinal mucosa of piglets. However, it was not possible to identify a specific antioxidant enzyme involved in counteracting the effect of DON." @default.
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• W1921294920 date "2015-12-01" @default.
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• W1921294920 title "Short Communication: Antioxidant capacity in the intestinal mucosa of weanling piglets fed diets containing Fusarium mycotoxins and the efficacy of commercial supplements sold as detoxifiers" @default.
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• W1921294920 doi "https://doi.org/10.4141/cjas-2015-037" @default.
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