FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1921751911> ?p ?o ?g. }

• W1921751911 endingPage "1259" @default.
• W1921751911 startingPage "1249" @default.
• W1921751911 abstract "Background: Periodontal disease is a major complication of type 1 diabetes mellitus (T1DM). The aim of the present study is to investigate the relationship between glycated hemoglobin and circulating levels of interleukin (IL)‐6, IL‐8, and C‐X‐C motif chemokine ligand 5 (CXCL5) in non‐smoking patients suffering from T1DM, with and without periodontitis. In addition, to determine the effect of advanced glycation end products (AGE) in the presence and absence of Porphyromonas gingivalis lipopolysaccharide (LPS) on IL‐6, IL‐8, and CXCL5 expression by THP‐1 monocytes and OKF6/TERT‐2 cells. Methods: There were 104 participants in the study: 19 healthy volunteers, 23 patients with periodontitis, 28 patients with T1DM, and 34 patients with T1DM and periodontitis. Levels of blood glucose/glycated hemoglobin (International Federation of Clinical Chemistry [IFCC]) were determined by high‐performance liquid chromatography. Levels of IL‐6, IL‐8, and CXCL5 in plasma were determined by enzyme‐linked immunosorbent assay (ELISA). In vitro stimulation of OKF6/TERT‐2 cells and THP‐1 monocytes was performed with combinations of AGE and P. gingivalis LPS. Changes in expression of IL‐6, IL‐8, and CXCL5 were monitored by ELISA and real‐time polymerase chain reaction. Results: Patients with diabetes and periodontitis had higher plasma levels of IL‐8 than patients with periodontitis alone. Plasma levels of IL‐8 correlated significantly with IFCC units, clinical probing depth, and attachment loss. AGE and LPS, alone or in combination, stimulated IL‐6, IL‐8, and CXCL5 expression in both OKF6/TERT‐2 cells and THP‐1 monocytes. Conclusions: Elevated plasma levels of IL‐8 potentially contribute to the cross‐susceptibility between periodontitis and T1DM. P. gingivalis LPS and AGE in combination caused significantly greater expression of IL‐6, IL‐8, and CXCL5 from THP‐1 monocytes and OKF6/TERT‐2 cells than LPS alone." @default.
• W1921751911 created "2016-06-24" @default.
• W1921751911 creator A5008206603 @default.
• W1921751911 creator A5012250913 @default.
• W1921751911 creator A5013072298 @default.
• W1921751911 creator A5020142441 @default.
• W1921751911 creator A5038791640 @default.
• W1921751911 creator A5056052011 @default.
• W1921751911 creator A5085571228 @default.
• W1921751911 date "2015-11-01" @default.
• W1921751911 modified "2023-10-06" @default.
• W1921751911 title "The Influence of Glycated Hemoglobin on the Cross Susceptibility Between Type 1 Diabetes Mellitus and Periodontal Disease" @default.
• W1921751911 cites W1519919967 @default.
• W1921751911 cites W1537337088 @default.
• W1921751911 cites W1897355343 @default.
• W1921751911 cites W1969559009 @default.
• W1921751911 cites W1977167754 @default.
• W1921751911 cites W1980339974 @default.
• W1921751911 cites W1982867208 @default.
• W1921751911 cites W1990805809 @default.
• W1921751911 cites W2001489577 @default.
• W1921751911 cites W2004971151 @default.
• W1921751911 cites W2018526657 @default.
• W1921751911 cites W2018539370 @default.
• W1921751911 cites W2018575169 @default.
• W1921751911 cites W2020444384 @default.
• W1921751911 cites W2022863283 @default.
• W1921751911 cites W2024425515 @default.
• W1921751911 cites W2031239046 @default.
• W1921751911 cites W2037064495 @default.
• W1921751911 cites W2043162778 @default.
• W1921751911 cites W2043212102 @default.
• W1921751911 cites W2043461295 @default.
• W1921751911 cites W2044097621 @default.
• W1921751911 cites W2044918883 @default.
• W1921751911 cites W2046223572 @default.
• W1921751911 cites W2056445185 @default.
• W1921751911 cites W2061397736 @default.
• W1921751911 cites W2066256489 @default.
• W1921751911 cites W2077547899 @default.
• W1921751911 cites W2077591662 @default.
• W1921751911 cites W2078536595 @default.
• W1921751911 cites W2092414718 @default.
• W1921751911 cites W2101044821 @default.
• W1921751911 cites W2107715779 @default.
• W1921751911 cites W2113835734 @default.
• W1921751911 cites W2114570899 @default.
• W1921751911 cites W2116823777 @default.
• W1921751911 cites W2116970392 @default.
• W1921751911 cites W2122028159 @default.
• W1921751911 cites W2122137463 @default.
• W1921751911 cites W2126071207 @default.
• W1921751911 cites W2127617459 @default.
• W1921751911 cites W2133811005 @default.
• W1921751911 cites W2136497196 @default.
• W1921751911 cites W2137951841 @default.
• W1921751911 cites W2142322940 @default.
• W1921751911 cites W2147854986 @default.
• W1921751911 cites W2148101485 @default.
• W1921751911 cites W2155333498 @default.
• W1921751911 cites W2156534751 @default.
• W1921751911 cites W2322774045 @default.
• W1921751911 doi "https://doi.org/10.1902/jop.2015.150149" @default.
• W1921751911 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26252750" @default.
• W1921751911 hasPublicationYear "2015" @default.
• W1921751911 type Work @default.
• W1921751911 sameAs 1921751911 @default.
• W1921751911 citedByCount "15" @default.
• W1921751911 countsByYear W19217519112018 @default.
• W1921751911 countsByYear W19217519112019 @default.
• W1921751911 countsByYear W19217519112020 @default.
• W1921751911 countsByYear W19217519112021 @default.
• W1921751911 countsByYear W19217519112022 @default.
• W1921751911 countsByYear W19217519112023 @default.
• W1921751911 crossrefType "journal-article" @default.
• W1921751911 hasAuthorship W1921751911A5008206603 @default.
• W1921751911 hasAuthorship W1921751911A5012250913 @default.
• W1921751911 hasAuthorship W1921751911A5013072298 @default.
• W1921751911 hasAuthorship W1921751911A5020142441 @default.
• W1921751911 hasAuthorship W1921751911A5038791640 @default.
• W1921751911 hasAuthorship W1921751911A5056052011 @default.
• W1921751911 hasAuthorship W1921751911A5085571228 @default.
• W1921751911 hasConcept C126322002 @default.
• W1921751911 hasConcept C134018914 @default.
• W1921751911 hasConcept C147990577 @default.
• W1921751911 hasConcept C203014093 @default.
• W1921751911 hasConcept C2777180221 @default.
• W1921751911 hasConcept C2777538456 @default.
• W1921751911 hasConcept C2778690821 @default.
• W1921751911 hasConcept C2778754761 @default.
• W1921751911 hasConcept C2779337755 @default.
• W1921751911 hasConcept C2780183776 @default.
• W1921751911 hasConcept C2780385504 @default.
• W1921751911 hasConcept C2781232474 @default.
• W1921751911 hasConcept C555293320 @default.
• W1921751911 hasConcept C71924100 @default.
• W1921751911 hasConcept C74172505 @default.
• W1921751911 hasConcept C90924648 @default.

• next