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- W1921994328 abstract "Studies were made on a number of 35 prepuberal Merinos cross breed femalesheep, three months age, equally divided in three experimental groups and one control group. Femalesin the experimental groups were given 0.2 ml/animal (2.5 mg/ml) hexoestrol diacetate,intramuscularly. After 30, 60, 90 and 120 days respectively, blood, urine, muscle tissue (by biopsy)samples were harvested in order to determine, through electrochemioiluminescence, the concentrationsof the residue of this steroidal compound. Ovaries were also harvested through ovarioectomy for histopathologicalexamination. The maximum levels of this hormone residue were identified in urine (theaverage value being 652,4 pg/ml, for group I), intermediate values in blood samples (43.74 pg/ml),while the muscle samples revealed concentrations inferior to the detection limit for the utilized method(18.4 pg/g). Atretic follicles were present in very large numbers, and the primordial follicle pool wasreduced by over 50% in the ovaries harvested from the experimental group. We can see that thehexestrol diacetate initiates and maintains the follicular atresia in young prepuberal female sheep, withdrastic reduction of the follicle pool, compromising the female reproductively." @default.
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- W1921994328 date "2012-01-01" @default.
- W1921994328 modified "2023-10-16" @default.
- W1921994328 title "Researches regarding the residue levels of 17β-estradiol in blood, urine and muscle in prepuberal sheep and their influence on follicular pool." @default.
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- W1921994328 doi "https://doi.org/10.15835/buasvmcn-vm:69:1-2:8877" @default.
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