FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1922022061> ?p ?o ?g. }

• W1922022061 endingPage "1010" @default.
• W1922022061 startingPage "1002" @default.
• W1922022061 abstract "ABSTRACT Following development, the avian brain continues to produce neurons throughout adulthood, which functionally integrate throughout the telencephalon, including the hippocampus. In food‐storing birds like the black‐capped chickadee ( Poecile atricapillus ), new neurons incorporated into the hippocampus are hypothesized to play a role in spatial learning. Previous results on the relation between hippocampal neurogenesis and spatial learning, however, are correlational. In this study, we experimentally suppressed hippocampal neuronal recruitment and tested for subsequent effects on spatial learning in adult chickadees. After chickadees exhibited significant learning, we treated birds with daily injections of either saline or methylazoxymethanol (MAM), a toxin that suppresses cell proliferation in the brain and monitored subsequent spatial learning. MAM treatment significantly reduced cell proliferation around the lateral ventricles and neuronal recruitment in the hippocampus, measured using the cell birth marker bromodeoxyuridine. MAM‐treated birds performed significantly worse than controls on the spatial learning task 12 days following the initiation of MAM treatment, a time when new neurons would begin functionally integrating into the hippocampus. This difference in learning, however, was limited to a single trial. MAM treatment did not affect any measure of body condition, suggesting learning impairments were not a product of non‐specific adverse effects of MAM. This is the first evidence of a potential causal link between hippocampal neurogenesis and spatial learning in birds. © 2014 Wiley Periodicals, Inc. Develop Neurobiol 74: 1002–1010, 2014" @default.
• W1922022061 created "2016-06-24" @default.
• W1922022061 creator A5006324003 @default.
• W1922022061 creator A5026281501 @default.
• W1922022061 creator A5083672438 @default.
• W1922022061 date "2014-04-28" @default.
• W1922022061 modified "2023-10-18" @default.
• W1922022061 title "Inhibition of cell proliferation in black‐capped chickadees suggests a role for neurogenesis in spatial learning" @default.
• W1922022061 cites W1670625131 @default.
• W1922022061 cites W1948148580 @default.
• W1922022061 cites W1976814021 @default.
• W1922022061 cites W1979072148 @default.
• W1922022061 cites W1979521457 @default.
• W1922022061 cites W1987865123 @default.
• W1922022061 cites W1993439788 @default.
• W1922022061 cites W2014097042 @default.
• W1922022061 cites W2015549918 @default.
• W1922022061 cites W2025604203 @default.
• W1922022061 cites W2026393786 @default.
• W1922022061 cites W2052321585 @default.
• W1922022061 cites W2055301723 @default.
• W1922022061 cites W2060850575 @default.
• W1922022061 cites W2068044304 @default.
• W1922022061 cites W2068118065 @default.
• W1922022061 cites W2080408963 @default.
• W1922022061 cites W2083339405 @default.
• W1922022061 cites W2086369996 @default.
• W1922022061 cites W2096972233 @default.
• W1922022061 cites W2099344713 @default.
• W1922022061 cites W2108189835 @default.
• W1922022061 cites W2114635736 @default.
• W1922022061 cites W2125912121 @default.
• W1922022061 cites W2129828559 @default.
• W1922022061 cites W2138888229 @default.
• W1922022061 cites W2145884075 @default.
• W1922022061 cites W2169364448 @default.
• W1922022061 cites W2411547940 @default.
• W1922022061 cites W4235049859 @default.
• W1922022061 cites W4366658041 @default.
• W1922022061 doi "https://doi.org/10.1002/dneu.22180" @default.
• W1922022061 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24723376" @default.
• W1922022061 hasPublicationYear "2014" @default.
• W1922022061 type Work @default.
• W1922022061 sameAs 1922022061 @default.
• W1922022061 citedByCount "16" @default.
• W1922022061 countsByYear W19220220612014 @default.
• W1922022061 countsByYear W19220220612015 @default.
• W1922022061 countsByYear W19220220612017 @default.
• W1922022061 countsByYear W19220220612018 @default.
• W1922022061 countsByYear W19220220612019 @default.
• W1922022061 countsByYear W19220220612022 @default.
• W1922022061 countsByYear W19220220612023 @default.
• W1922022061 crossrefType "journal-article" @default.
• W1922022061 hasAuthorship W1922022061A5006324003 @default.
• W1922022061 hasAuthorship W1922022061A5026281501 @default.
• W1922022061 hasAuthorship W1922022061A5083672438 @default.
• W1922022061 hasConcept C148762608 @default.
• W1922022061 hasConcept C169760540 @default.
• W1922022061 hasConcept C2778260397 @default.
• W1922022061 hasConcept C2780744974 @default.
• W1922022061 hasConcept C2781161787 @default.
• W1922022061 hasConcept C2985665543 @default.
• W1922022061 hasConcept C4746552 @default.
• W1922022061 hasConcept C529278444 @default.
• W1922022061 hasConcept C533869091 @default.
• W1922022061 hasConcept C54355233 @default.
• W1922022061 hasConcept C62112901 @default.
• W1922022061 hasConcept C86803240 @default.
• W1922022061 hasConceptScore W1922022061C148762608 @default.
• W1922022061 hasConceptScore W1922022061C169760540 @default.
• W1922022061 hasConceptScore W1922022061C2778260397 @default.
• W1922022061 hasConceptScore W1922022061C2780744974 @default.
• W1922022061 hasConceptScore W1922022061C2781161787 @default.
• W1922022061 hasConceptScore W1922022061C2985665543 @default.
• W1922022061 hasConceptScore W1922022061C4746552 @default.
• W1922022061 hasConceptScore W1922022061C529278444 @default.
• W1922022061 hasConceptScore W1922022061C533869091 @default.
• W1922022061 hasConceptScore W1922022061C54355233 @default.
• W1922022061 hasConceptScore W1922022061C62112901 @default.
• W1922022061 hasConceptScore W1922022061C86803240 @default.
• W1922022061 hasFunder F4320334593 @default.
• W1922022061 hasIssue "10" @default.
• W1922022061 hasLocation W19220220611 @default.
• W1922022061 hasLocation W19220220612 @default.
• W1922022061 hasOpenAccess W1922022061 @default.
• W1922022061 hasPrimaryLocation W19220220611 @default.
• W1922022061 hasRelatedWork W1965527402 @default.
• W1922022061 hasRelatedWork W1979615967 @default.
• W1922022061 hasRelatedWork W1979973324 @default.
• W1922022061 hasRelatedWork W1982025080 @default.
• W1922022061 hasRelatedWork W1996820781 @default.
• W1922022061 hasRelatedWork W2076432328 @default.
• W1922022061 hasRelatedWork W2154908600 @default.
• W1922022061 hasRelatedWork W2358684204 @default.
• W1922022061 hasRelatedWork W2468411290 @default.
• W1922022061 hasRelatedWork W3173887211 @default.
• W1922022061 hasVolume "74" @default.
• W1922022061 isParatext "false" @default.

• next