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- W192233927 abstract "No AccessJournal of Urology1 Jun 1987Production of Penile Veno-Occlusive Insufficiency by Arterial Occlusion in a Canine Model Joseph J. Bookstein, Thomas Machado, and Donald Rippon Joseph J. BooksteinJoseph J. Bookstein More articles by this author , Thomas MachadoThomas Machado More articles by this author , and Donald RipponDonald Rippon More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)44483-1AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Angiographic evaluation of impotent men revealed a frequent association between penile arterial disease and veno-occlusive insufficiency of the corpora cavernosa. In order to evaluate a possible cause-and-effect relationship, we investigated the competence of the cavernosal veno-occlusive mechanism in a canine model at various intervals after onset of cavernosal ischemia. In most dogs, the veno-occlusive mechanism could no longer be activated by papaverine after about 30 minutes of ischemia. If ischemia was relieved shortly thereafter, veno-occlusive competence returned after a further delay of one or two hours. The evidence suggests that veno-occlusive failure is not simply a hemodynamic consequence of loss of arterial inflow, but instead secondary to some ischemic injury. We conclude that arterial insufficiency may be one of the causes of cavernosal veno-occlusive insufficiency in humans. © 1987 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited ByAzadzoi K, Park K, Andry C, Goldstein I and Siroky M (2018) Relationship Between Cavernosal Ischemia and Corporal Veno-Occlusive Dysfunction in an Animal ModelJournal of Urology, VOL. 157, NO. 3, (1011-1017), Online publication date: 1-Mar-1997.Azadzoi K, Siroky M and Goldstein I (2018) Study of Etiologic Relationship of Arterial Atherosclerosis to Corporal Veno-Occlusive Dysfunction in the RabbitJournal of Urology, VOL. 155, NO. 5, (1795-1800), Online publication date: 1-May-1996.Wespes E and Schulman C (2018) Venous Impotence: Pathophysiology, Diagnosis and TreatmentJournal of Urology, VOL. 149, NO. 5 Part 2, (1238-1245), Online publication date: 1-May-1993.Vickers M, Benson C and Richie J (2018) High resolution ultrasonography and pulsed wave doppler for detection of corporovenous incompetence In erectile dysfunctionJournal of Urology, VOL. 143, NO. 6, (1125-1127), Online publication date: 1-Jun-1990.Kirkeby H, Forman A, Sørensen S and Andersson K (2018) Alpha-Adrenoceptor Function in Isolated Penile Circumflex Veins from Potent and Impotent MenJournal of Urology, VOL. 142, NO. 5, (1369-1371), Online publication date: 1-Nov-1989. Volume 137Issue 6June 1987Page: 1283-1286 Advertisement Copyright & Permissions© 1987 by The American Urological Association Education and Research, Inc.MetricsAuthor Information Joseph J. Bookstein More articles by this author Thomas Machado More articles by this author Donald Rippon More articles by this author Expand All Advertisement PDF DownloadLoading ..." @default.
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- W192233927 title "Production of Penile Veno-Occlusive Insufficiency by Arterial Occlusion in a Canine Model" @default.
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