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• W1922784911 startingPage "729" @default.
• W1922784911 abstract "Abstract New chromosome rearrangements were found in 10% or more of mitotically stable transformants. This was shown for transformations involving a variety of different markers, vectors and recipient strains. Breakpoints were randomly distributed among the seven linkage groups. Controls using untransformed protoplasts of the same strains contained almost no rearrangements. A study of molecularly characterized Am+ transformants showed that rearrangements are frequent when multiple ectopic integration events have occurred. In contrast, rearrangements are absent or infrequent when only the resident locus is restored to am+ by a homologous event. Sequences of the transforming vector were genetically linked to breakpoints in 6 of 10 translocations that were examined using Southern hybridization or colony blots." @default.
• W1922784911 created "2016-06-24" @default.
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• W1922784911 date "1993-07-01" @default.
• W1922784911 modified "2023-10-14" @default.
• W1922784911 title "Chromosome rearrangements recovered following transformation of Neurospora crassa." @default.
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• W1922784911 doi "https://doi.org/10.1093/genetics/134.3.729" @default.
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