FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1923260397> ?p ?o ?g. }

• W1923260397 endingPage "9595" @default.
• W1923260397 startingPage "9591" @default.
• W1923260397 abstract "We report a novel spherical nucleic acid (SNA) gold nanoparticle conjugate, termed the Sticky-flare, which enables facile quantification of RNA expression in live cells and spatiotemporal analysis of RNA transport and localization. The Sticky-flare is capable of entering live cells without the need for transfection agents and recognizing target RNA transcripts in a sequence-specific manner. On recognition, the Sticky-flare transfers a fluorophore-conjugated reporter to the transcript, resulting in a turning on of fluorescence in a quantifiable manner and the fluorescent labeling of targeted transcripts. The latter allows the RNA to be tracked via fluorescence microscopy as it is transported throughout the cell. We use this novel nanoconjugate to analyze the expression level and spatial distribution of β-actin mRNA in HeLa cells and to observe the real-time transport of β-actin mRNA in mouse embryonic fibroblasts. Furthermore, we investigate the application of Sticky-flares for tracking transcripts that undergo more extensive compartmentalization by fluorophore-labeling U1 small nuclear RNA and observing its distribution in the nucleus of live cells." @default.
• W1923260397 created "2016-06-24" @default.
• W1923260397 creator A5005216445 @default.
• W1923260397 creator A5012068616 @default.
• W1923260397 creator A5020506543 @default.
• W1923260397 creator A5055829204 @default.
• W1923260397 creator A5075746949 @default.
• W1923260397 date "2015-07-20" @default.
• W1923260397 modified "2023-10-18" @default.
• W1923260397 title "Quantification and real-time tracking of RNA in live cells using Sticky-flares" @default.
• W1923260397 cites W1976135176 @default.
• W1923260397 cites W1976647752 @default.
• W1923260397 cites W1977569722 @default.
• W1923260397 cites W1983677072 @default.
• W1923260397 cites W1993141849 @default.
• W1923260397 cites W1994357966 @default.
• W1923260397 cites W2002760096 @default.
• W1923260397 cites W2006789189 @default.
• W1923260397 cites W2006878368 @default.
• W1923260397 cites W2009993736 @default.
• W1923260397 cites W2010447672 @default.
• W1923260397 cites W2028317903 @default.
• W1923260397 cites W2042789810 @default.
• W1923260397 cites W2047569375 @default.
• W1923260397 cites W2049222491 @default.
• W1923260397 cites W2049628338 @default.
• W1923260397 cites W2052936390 @default.
• W1923260397 cites W2054091111 @default.
• W1923260397 cites W2072164275 @default.
• W1923260397 cites W2082965230 @default.
• W1923260397 cites W2100323976 @default.
• W1923260397 cites W2121322725 @default.
• W1923260397 cites W2126020016 @default.
• W1923260397 cites W2127540003 @default.
• W1923260397 cites W2129191745 @default.
• W1923260397 cites W2136579137 @default.
• W1923260397 cites W2137158680 @default.
• W1923260397 cites W2137248467 @default.
• W1923260397 cites W2139556632 @default.
• W1923260397 cites W2155095415 @default.
• W1923260397 cites W2332645767 @default.
• W1923260397 cites W2338873717 @default.
• W1923260397 cites W2495055847 @default.
• W1923260397 cites W4237229340 @default.
• W1923260397 cites W4362217323 @default.
• W1923260397 doi "https://doi.org/10.1073/pnas.1510581112" @default.
• W1923260397 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4534211" @default.
• W1923260397 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26195734" @default.
• W1923260397 hasPublicationYear "2015" @default.
• W1923260397 type Work @default.
• W1923260397 sameAs 1923260397 @default.
• W1923260397 citedByCount "96" @default.
• W1923260397 countsByYear W19232603972015 @default.
• W1923260397 countsByYear W19232603972016 @default.
• W1923260397 countsByYear W19232603972017 @default.
• W1923260397 countsByYear W19232603972018 @default.
• W1923260397 countsByYear W19232603972019 @default.
• W1923260397 countsByYear W19232603972020 @default.
• W1923260397 countsByYear W19232603972021 @default.
• W1923260397 countsByYear W19232603972022 @default.
• W1923260397 countsByYear W19232603972023 @default.
• W1923260397 crossrefType "journal-article" @default.
• W1923260397 hasAuthorship W1923260397A5005216445 @default.
• W1923260397 hasAuthorship W1923260397A5012068616 @default.
• W1923260397 hasAuthorship W1923260397A5020506543 @default.
• W1923260397 hasAuthorship W1923260397A5055829204 @default.
• W1923260397 hasAuthorship W1923260397A5075746949 @default.
• W1923260397 hasBestOaLocation W19232603971 @default.
• W1923260397 hasConcept C104317684 @default.
• W1923260397 hasConcept C105580179 @default.
• W1923260397 hasConcept C121332964 @default.
• W1923260397 hasConcept C1491633281 @default.
• W1923260397 hasConcept C153911025 @default.
• W1923260397 hasConcept C15526883 @default.
• W1923260397 hasConcept C185592680 @default.
• W1923260397 hasConcept C2778617687 @default.
• W1923260397 hasConcept C54009773 @default.
• W1923260397 hasConcept C54355233 @default.
• W1923260397 hasConcept C55493867 @default.
• W1923260397 hasConcept C62520636 @default.
• W1923260397 hasConcept C67705224 @default.
• W1923260397 hasConcept C81885089 @default.
• W1923260397 hasConcept C86803240 @default.
• W1923260397 hasConcept C91881484 @default.
• W1923260397 hasConcept C95444343 @default.
• W1923260397 hasConceptScore W1923260397C104317684 @default.
• W1923260397 hasConceptScore W1923260397C105580179 @default.
• W1923260397 hasConceptScore W1923260397C121332964 @default.
• W1923260397 hasConceptScore W1923260397C1491633281 @default.
• W1923260397 hasConceptScore W1923260397C153911025 @default.
• W1923260397 hasConceptScore W1923260397C15526883 @default.
• W1923260397 hasConceptScore W1923260397C185592680 @default.
• W1923260397 hasConceptScore W1923260397C2778617687 @default.
• W1923260397 hasConceptScore W1923260397C54009773 @default.
• W1923260397 hasConceptScore W1923260397C54355233 @default.
• W1923260397 hasConceptScore W1923260397C55493867 @default.
• W1923260397 hasConceptScore W1923260397C62520636 @default.
• W1923260397 hasConceptScore W1923260397C67705224 @default.

• next