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- W1924015087 endingPage "169" @default.
- W1924015087 startingPage "143" @default.
- W1924015087 abstract "Early in the course of evolution open chain tetrapyrrolic compounds played a central metabolic role. The accessory photosynthetic of certain unicellular plant organisms are structurally related to the and are formed by (enzymatic) metabolic pathways similar to those leading to the formation of bilirubin.1 Indeed, these plant bile pigments trap light for the photosynthetic evolution of oxygen more efficiently than does chlorophyll itselr.t In humans and other vertebrate species the process of pigment formation is recalled for significant, but less central metabolic processes. The pigmen~ are a waste product, the potentially toxic end-stage of the catabolism of hemoglobin and heme-containing enzymes. Nevertheless, despite this subsidiary role, pigment metabolism has continued to excite the imagination of biochemical and clinical investigators since the tum of the century. The past several years have been a period of especially intensive study. Techniques have been devised for radiolabeling bilirubin and many of its derivatives. The availability of these tracer materials has greatly facilitated the investigation of pigment formation and elimination. The biosynthesis of early labeled bilirubin," @default.
- W1924015087 created "2016-06-24" @default.
- W1924015087 creator A5019271587 @default.
- W1924015087 creator A5041694308 @default.
- W1924015087 date "1969-01-01" @default.
- W1924015087 modified "2023-09-23" @default.
- W1924015087 title "Recent Advances in Bile Pigment Metabolism" @default.
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