FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1924582377> ?p ?o ?g. }

• W1924582377 endingPage "53" @default.
• W1924582377 startingPage "40" @default.
• W1924582377 abstract "The concepts of pathogenicity and virulence have governed our perception of microbial harmfulness since the time of Pasteur and Koch. These concepts resulted in the recognition and identification of numerous etiological agents and provided natural and synthetic agents effective in therapy and prevention of diseases. However, Koch's postulates--the premier product of this view--place the onus of harmfulness solely on the microbial world. Our recent experiences with polymicrobic and nosocomial infections, legionellosis, and acquired immunodeficiency syndrome point to the host as the major determinant of disease. The principles of parasitism, enunciated by Theobold Smith, approximate more accurately the disturbances of the host-parasite equilibrium we designate as infection. Many complex attributes of microbial anatomy and physiology have been obscured by our dependency on the pure-culture technique. For example, bacterial attachment organelles and the production of exopolysaccharides enable microorganisms to interact with mammalian glycocalyces and specific receptors. In addition, selection, through the use of therapeutic agents, aids in the progression of environmental organisms to members of the intimate human biosphere, with the potential to complicate the recovery of patients. These factors emphasize further the pivotal significance of host reactions in infections. Parasitism, in its negative aspects, explains the emergence of new infections that involve harm to more than host organs and cells: we may encounter subtler infections that reveal parasitic and host cell nucleic acid interactions in a form of genomic parasitism." @default.
• W1924582377 created "2016-06-24" @default.
• W1924582377 creator A5038482236 @default.
• W1924582377 date "1988-01-01" @default.
• W1924582377 modified "2023-09-26" @default.
• W1924582377 title "Pathogenicity and virulence: another view" @default.
• W1924582377 cites W1494210286 @default.
• W1924582377 cites W1497300983 @default.
• W1924582377 cites W1597088653 @default.
• W1924582377 cites W182210339 @default.
• W1924582377 cites W1835640114 @default.
• W1924582377 cites W1869207639 @default.
• W1924582377 cites W1886178995 @default.
• W1924582377 cites W1917295332 @default.
• W1924582377 cites W1932485333 @default.
• W1924582377 cites W1971673998 @default.
• W1924582377 cites W1974315097 @default.
• W1924582377 cites W1999053228 @default.
• W1924582377 cites W2015476924 @default.
• W1924582377 cites W2015915038 @default.
• W1924582377 cites W2025474188 @default.
• W1924582377 cites W2037487270 @default.
• W1924582377 cites W2050509711 @default.
• W1924582377 cites W2059795727 @default.
• W1924582377 cites W2072424528 @default.
• W1924582377 cites W2076781184 @default.
• W1924582377 cites W2083238051 @default.
• W1924582377 cites W2104164228 @default.
• W1924582377 cites W2104329399 @default.
• W1924582377 cites W2109512535 @default.
• W1924582377 cites W2111233616 @default.
• W1924582377 cites W2115042116 @default.
• W1924582377 cites W2133370138 @default.
• W1924582377 cites W2137567526 @default.
• W1924582377 cites W2142692636 @default.
• W1924582377 cites W2149351690 @default.
• W1924582377 cites W2150001528 @default.
• W1924582377 cites W2172669044 @default.
• W1924582377 cites W2172882969 @default.
• W1924582377 cites W2175614871 @default.
• W1924582377 cites W2180795626 @default.
• W1924582377 cites W2237925708 @default.
• W1924582377 cites W2317196206 @default.
• W1924582377 cites W2337484707 @default.
• W1924582377 cites W4211159080 @default.
• W1924582377 cites W4230984516 @default.
• W1924582377 cites W4249612468 @default.
• W1924582377 cites W52372750 @default.
• W1924582377 cites W73954871 @default.
• W1924582377 doi "https://doi.org/10.1128/cmr.1.1.40" @default.
• W1924582377 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/358028" @default.
• W1924582377 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3060244" @default.
• W1924582377 hasPublicationYear "1988" @default.
• W1924582377 type Work @default.
• W1924582377 sameAs 1924582377 @default.
• W1924582377 citedByCount "71" @default.
• W1924582377 countsByYear W19245823772013 @default.
• W1924582377 countsByYear W19245823772014 @default.
• W1924582377 countsByYear W19245823772015 @default.
• W1924582377 countsByYear W19245823772016 @default.
• W1924582377 countsByYear W19245823772017 @default.
• W1924582377 countsByYear W19245823772018 @default.
• W1924582377 countsByYear W19245823772019 @default.
• W1924582377 countsByYear W19245823772020 @default.
• W1924582377 countsByYear W19245823772021 @default.
• W1924582377 countsByYear W19245823772023 @default.
• W1924582377 crossrefType "journal-article" @default.
• W1924582377 hasAuthorship W1924582377A5038482236 @default.
• W1924582377 hasBestOaLocation W19245823771 @default.
• W1924582377 hasConcept C104317684 @default.
• W1924582377 hasConcept C126831891 @default.
• W1924582377 hasConcept C137858568 @default.
• W1924582377 hasConcept C142724271 @default.
• W1924582377 hasConcept C18903297 @default.
• W1924582377 hasConcept C203014093 @default.
• W1924582377 hasConcept C2778234367 @default.
• W1924582377 hasConcept C2779134260 @default.
• W1924582377 hasConcept C54355233 @default.
• W1924582377 hasConcept C60987743 @default.
• W1924582377 hasConcept C64502627 @default.
• W1924582377 hasConcept C71924100 @default.
• W1924582377 hasConcept C86803240 @default.
• W1924582377 hasConcept C89423630 @default.
• W1924582377 hasConceptScore W1924582377C104317684 @default.
• W1924582377 hasConceptScore W1924582377C126831891 @default.
• W1924582377 hasConceptScore W1924582377C137858568 @default.
• W1924582377 hasConceptScore W1924582377C142724271 @default.
• W1924582377 hasConceptScore W1924582377C18903297 @default.
• W1924582377 hasConceptScore W1924582377C203014093 @default.
• W1924582377 hasConceptScore W1924582377C2778234367 @default.
• W1924582377 hasConceptScore W1924582377C2779134260 @default.
• W1924582377 hasConceptScore W1924582377C54355233 @default.
• W1924582377 hasConceptScore W1924582377C60987743 @default.
• W1924582377 hasConceptScore W1924582377C64502627 @default.
• W1924582377 hasConceptScore W1924582377C71924100 @default.
• W1924582377 hasConceptScore W1924582377C86803240 @default.
• W1924582377 hasConceptScore W1924582377C89423630 @default.
• W1924582377 hasIssue "1" @default.

• next