Matches in SemOpenAlex for { <https://semopenalex.org/work/W192527350> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- W192527350 endingPage "7" @default.
- W192527350 startingPage "2561" @default.
- W192527350 abstract "In a one-stage, interleukin-2 (IL-2), limiting-dilution analysis, peripheral blood mononuclear cells from patients with uveitis and normal control subjects were assayed for S-antigen specific, tetanus-specific, and in vivo activated helper T cells. Controls subjects consistently demonstrated tetanus-specific responses, but neither in vivo activation nor S-antigen specific helper T cell responses were seen. Patients with active forms of diffuse, posterior, and anterior uveitis were found to have significant frequencies of both in vivo activated and S-antigen specific helper T cells in their peripheral blood. These data show that patients with certain forms of uveitis have a measurable frequency of lymphocytes in the peripheral immunologic compartment capable of secreting IL-2 in response to autologous presentation of ocular autoantigen (S-antigen). Limiting-dilution analysis techniques, generating minimal responder cell frequency estimates and distinct IL secretion patterns, may provide an index of disease activity and critical information about the mechanism(s) of ocular inflammation." @default.
- W192527350 created "2016-06-24" @default.
- W192527350 creator A5003551392 @default.
- W192527350 creator A5048470519 @default.
- W192527350 creator A5049474251 @default.
- W192527350 creator A5053977183 @default.
- W192527350 creator A5072264281 @default.
- W192527350 date "1991-08-01" @default.
- W192527350 modified "2023-09-27" @default.
- W192527350 title "Enumeration of autoreactive helper T lymphocytes in uveitis." @default.
- W192527350 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1831187" @default.
- W192527350 hasPublicationYear "1991" @default.
- W192527350 type Work @default.
- W192527350 sameAs 192527350 @default.
- W192527350 citedByCount "5" @default.
- W192527350 crossrefType "journal-article" @default.
- W192527350 hasAuthorship W192527350A5003551392 @default.
- W192527350 hasAuthorship W192527350A5048470519 @default.
- W192527350 hasAuthorship W192527350A5049474251 @default.
- W192527350 hasAuthorship W192527350A5053977183 @default.
- W192527350 hasAuthorship W192527350A5072264281 @default.
- W192527350 hasConcept C137061746 @default.
- W192527350 hasConcept C147483822 @default.
- W192527350 hasConcept C150903083 @default.
- W192527350 hasConcept C202751555 @default.
- W192527350 hasConcept C203014093 @default.
- W192527350 hasConcept C207001950 @default.
- W192527350 hasConcept C2776090121 @default.
- W192527350 hasConcept C2776194053 @default.
- W192527350 hasConcept C2781136212 @default.
- W192527350 hasConcept C55493867 @default.
- W192527350 hasConcept C71924100 @default.
- W192527350 hasConcept C86803240 @default.
- W192527350 hasConcept C8891405 @default.
- W192527350 hasConceptScore W192527350C137061746 @default.
- W192527350 hasConceptScore W192527350C147483822 @default.
- W192527350 hasConceptScore W192527350C150903083 @default.
- W192527350 hasConceptScore W192527350C202751555 @default.
- W192527350 hasConceptScore W192527350C203014093 @default.
- W192527350 hasConceptScore W192527350C207001950 @default.
- W192527350 hasConceptScore W192527350C2776090121 @default.
- W192527350 hasConceptScore W192527350C2776194053 @default.
- W192527350 hasConceptScore W192527350C2781136212 @default.
- W192527350 hasConceptScore W192527350C55493867 @default.
- W192527350 hasConceptScore W192527350C71924100 @default.
- W192527350 hasConceptScore W192527350C86803240 @default.
- W192527350 hasConceptScore W192527350C8891405 @default.
- W192527350 hasIssue "9" @default.
- W192527350 hasLocation W1925273501 @default.
- W192527350 hasOpenAccess W192527350 @default.
- W192527350 hasPrimaryLocation W1925273501 @default.
- W192527350 hasRelatedWork W1967254489 @default.
- W192527350 hasRelatedWork W2012012488 @default.
- W192527350 hasRelatedWork W2018967411 @default.
- W192527350 hasRelatedWork W2028497726 @default.
- W192527350 hasRelatedWork W2069039175 @default.
- W192527350 hasRelatedWork W2077024982 @default.
- W192527350 hasRelatedWork W2080019390 @default.
- W192527350 hasRelatedWork W2139188664 @default.
- W192527350 hasRelatedWork W2381196212 @default.
- W192527350 hasRelatedWork W2399441587 @default.
- W192527350 hasVolume "32" @default.
- W192527350 isParatext "false" @default.
- W192527350 isRetracted "false" @default.
- W192527350 magId "192527350" @default.
- W192527350 workType "article" @default.