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• W1925671842 endingPage "219" @default.
• W1925671842 startingPage "195" @default.
• W1925671842 abstract "Neuropeptides are important mediators both within the nervous system and between neurons and other cell types. Neuropeptides such as substance P, calcitonin gene-related peptide and neuropeptide Y (NPY), vasoactive intestinal polypeptide, somatostatin and corticotropin-releasing factor are also likely to play a role in the bidirectional gut-brain communication. In this capacity they may influence the activity of the gastrointestinal microbiota and its interaction with the gut-brain axis. Current efforts in elucidating the implication of neuropeptides in the microbiota-gut-brain axis address four information carriers from the gut to the brain (vagal and spinal afferent neurons; immune mediators such as cytokines; gut hormones; gut microbiota-derived signalling molecules) and four information carriers from the central nervous system to the gut (sympathetic efferent neurons; parasympathetic efferent neurons; neuroendocrine factors involving the adrenal medulla; neuroendocrine factors involving the adrenal cortex). Apart from operating as neurotransmitters, many biologically active peptides also function as gut hormones. Given that neuropeptides and gut hormones target the same cell membrane receptors (typically G protein-coupled receptors), the two messenger roles often converge in the same or similar biological implications. This is exemplified by NPY and peptide YY (PYY), two members of the PP-fold peptide family. While PYY is almost exclusively expressed by enteroendocrine cells, NPY is found at all levels of the gut-brain and brain-gut axis. The function of PYY-releasing enteroendocrine cells is directly influenced by short chain fatty acids generated by the intestinal microbiota from indigestible fibre, while NPY may control the impact of the gut microbiota on inflammatory processes, pain, brain function and behaviour. Although the impact of neuropeptides on the interaction between the gut microbiota and brain awaits to be analysed, biologically active peptides are likely to emerge as neural and endocrine messengers in orchestrating the microbiota-gut-brain axis in health and disease." @default.
• W1925671842 created "2016-06-24" @default.
• W1925671842 creator A5005473061 @default.
• W1925671842 creator A5006371344 @default.
• W1925671842 date "2014-01-01" @default.
• W1925671842 modified "2023-10-10" @default.
• W1925671842 title "Neuropeptides and the Microbiota-Gut-Brain Axis" @default.
• W1925671842 cites W1483363426 @default.
• W1925671842 cites W1508453404 @default.
• W1925671842 cites W1582832380 @default.
• W1925671842 cites W1594519739 @default.
• W1925671842 cites W176220091 @default.
• W1925671842 cites W1780023862 @default.
• W1925671842 cites W186721265 @default.
• W1925671842 cites W1920510593 @default.
• W1925671842 cites W1953598751 @default.
• W1925671842 cites W1964244234 @default.
• W1925671842 cites W1966217983 @default.
• W1925671842 cites W1966470298 @default.
• W1925671842 cites W1968294128 @default.
• W1925671842 cites W1971899867 @default.
• W1925671842 cites W1973436974 @default.
• W1925671842 cites W1974648798 @default.
• W1925671842 cites W1976198811 @default.
• W1925671842 cites W1978713113 @default.
• W1925671842 cites W1980634737 @default.
• W1925671842 cites W1980651822 @default.
• W1925671842 cites W1981364522 @default.
• W1925671842 cites W1981500982 @default.
• W1925671842 cites W1987192212 @default.
• W1925671842 cites W1987593207 @default.
• W1925671842 cites W1987735575 @default.
• W1925671842 cites W1987995892 @default.
• W1925671842 cites W1990350561 @default.
• W1925671842 cites W1991738959 @default.
• W1925671842 cites W1992406470 @default.
• W1925671842 cites W1994802618 @default.
• W1925671842 cites W1996006541 @default.
• W1925671842 cites W1996022100 @default.
• W1925671842 cites W1996116694 @default.
• W1925671842 cites W2002118002 @default.
• W1925671842 cites W2003961228 @default.
• W1925671842 cites W2003982930 @default.
• W1925671842 cites W2008522648 @default.
• W1925671842 cites W2010055058 @default.
• W1925671842 cites W2011118191 @default.
• W1925671842 cites W2012490955 @default.
• W1925671842 cites W2014436033 @default.
• W1925671842 cites W2016586816 @default.
• W1925671842 cites W2017366080 @default.
• W1925671842 cites W2017902019 @default.
• W1925671842 cites W2018041498 @default.
• W1925671842 cites W2021460779 @default.
• W1925671842 cites W2022957057 @default.
• W1925671842 cites W2026926998 @default.
• W1925671842 cites W2028909201 @default.
• W1925671842 cites W2029071453 @default.
• W1925671842 cites W2030500910 @default.
• W1925671842 cites W2035132856 @default.
• W1925671842 cites W2035451874 @default.
• W1925671842 cites W2037907937 @default.
• W1925671842 cites W2040534684 @default.
• W1925671842 cites W2040892689 @default.
• W1925671842 cites W2045833477 @default.
• W1925671842 cites W2046601873 @default.
• W1925671842 cites W2047775628 @default.
• W1925671842 cites W2047798386 @default.
• W1925671842 cites W2049685991 @default.
• W1925671842 cites W2055959752 @default.
• W1925671842 cites W2057891407 @default.
• W1925671842 cites W2057908401 @default.
• W1925671842 cites W2059246483 @default.
• W1925671842 cites W2061212294 @default.
• W1925671842 cites W2061559910 @default.
• W1925671842 cites W2064756281 @default.
• W1925671842 cites W2067273260 @default.
• W1925671842 cites W2069380892 @default.
• W1925671842 cites W2070238423 @default.
• W1925671842 cites W2072016770 @default.
• W1925671842 cites W2074537715 @default.
• W1925671842 cites W2074647381 @default.
• W1925671842 cites W2075583206 @default.
• W1925671842 cites W2075817261 @default.
• W1925671842 cites W2076260247 @default.
• W1925671842 cites W2079007392 @default.
• W1925671842 cites W2081203110 @default.
• W1925671842 cites W2081774207 @default.
• W1925671842 cites W2082737800 @default.
• W1925671842 cites W2082901516 @default.
• W1925671842 cites W2086380824 @default.
• W1925671842 cites W2087843844 @default.
• W1925671842 cites W2088170171 @default.
• W1925671842 cites W2088610222 @default.
• W1925671842 cites W2090836952 @default.
• W1925671842 cites W2091886883 @default.
• W1925671842 cites W2092894985 @default.
• W1925671842 cites W2093356923 @default.
• W1925671842 cites W2093500216 @default.

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