Matches in SemOpenAlex for { <https://semopenalex.org/work/W1925722892> ?p ?o ?g. }
- W1925722892 endingPage "2801" @default.
- W1925722892 startingPage "2785" @default.
- W1925722892 abstract "Unless stimulated by a chronic inflammatory agent, such as mineral oil, plasma cell tumors are rare in young BALB/c mice. This raises the questions: What do inflammatory tissues provide to promote mutagenesis? And what is the nature of mutagenesis? We determined that mineral oil‐induced plasmacytomas produce large amounts of endogenous retroelements—ecotropic and polytropic murine leukemia virus and intracisternal A particles. Therefore, plasmacytoma formation might occur, in part, by de novo insertion of these retroelements, induced or helped by the inflammation. We recovered up to ten de novo insertions in a single plasmacytoma, mostly in genes with common retroviral integration sites. Additional integrations accompany tumor evolution from a solid tumor through several generations in cell culture. The high frequency of de novo integrations into cancer genes suggests that endogenous retroelements are coresponsible for plasmacytoma formation and progression in BALB/c mice." @default.
- W1925722892 created "2016-06-24" @default.
- W1925722892 creator A5015837535 @default.
- W1925722892 creator A5021390331 @default.
- W1925722892 creator A5021685638 @default.
- W1925722892 creator A5040688856 @default.
- W1925722892 creator A5042362492 @default.
- W1925722892 creator A5046660376 @default.
- W1925722892 creator A5049928231 @default.
- W1925722892 creator A5084604266 @default.
- W1925722892 date "2014-09-01" @default.
- W1925722892 modified "2023-10-16" @default.
- W1925722892 title "Insertional hypermutation in mineral oil-induced plasmacytomas" @default.
- W1925722892 cites W1040845057 @default.
- W1925722892 cites W1491071216 @default.
- W1925722892 cites W1492624463 @default.
- W1925722892 cites W1502614921 @default.
- W1925722892 cites W1517361621 @default.
- W1925722892 cites W1597595254 @default.
- W1925722892 cites W1842459448 @default.
- W1925722892 cites W1916323221 @default.
- W1925722892 cites W1930048155 @default.
- W1925722892 cites W1960601813 @default.
- W1925722892 cites W1967174633 @default.
- W1925722892 cites W1970883381 @default.
- W1925722892 cites W1981809827 @default.
- W1925722892 cites W1982297304 @default.
- W1925722892 cites W1984567979 @default.
- W1925722892 cites W1995866508 @default.
- W1925722892 cites W1996660822 @default.
- W1925722892 cites W2000589976 @default.
- W1925722892 cites W2000902003 @default.
- W1925722892 cites W2001717481 @default.
- W1925722892 cites W2017223857 @default.
- W1925722892 cites W2024985626 @default.
- W1925722892 cites W2036249353 @default.
- W1925722892 cites W2037305324 @default.
- W1925722892 cites W2037586575 @default.
- W1925722892 cites W2043680651 @default.
- W1925722892 cites W2043743047 @default.
- W1925722892 cites W2045807857 @default.
- W1925722892 cites W2052321293 @default.
- W1925722892 cites W2053772964 @default.
- W1925722892 cites W2056355023 @default.
- W1925722892 cites W2059225262 @default.
- W1925722892 cites W2061222660 @default.
- W1925722892 cites W2063855257 @default.
- W1925722892 cites W2069829573 @default.
- W1925722892 cites W2070650234 @default.
- W1925722892 cites W2075507370 @default.
- W1925722892 cites W2079664984 @default.
- W1925722892 cites W2079694375 @default.
- W1925722892 cites W2080047282 @default.
- W1925722892 cites W2082367347 @default.
- W1925722892 cites W2086218387 @default.
- W1925722892 cites W2086784756 @default.
- W1925722892 cites W2094956110 @default.
- W1925722892 cites W2101035019 @default.
- W1925722892 cites W2102730296 @default.
- W1925722892 cites W2105835660 @default.
- W1925722892 cites W2106393512 @default.
- W1925722892 cites W2114367637 @default.
- W1925722892 cites W2118734051 @default.
- W1925722892 cites W2119830220 @default.
- W1925722892 cites W2122241386 @default.
- W1925722892 cites W2122838060 @default.
- W1925722892 cites W2128056949 @default.
- W1925722892 cites W2128408747 @default.
- W1925722892 cites W2130109189 @default.
- W1925722892 cites W2136640137 @default.
- W1925722892 cites W2139106521 @default.
- W1925722892 cites W2139199450 @default.
- W1925722892 cites W2160278978 @default.
- W1925722892 cites W2168909179 @default.
- W1925722892 cites W2246071760 @default.
- W1925722892 cites W2325299883 @default.
- W1925722892 cites W4235521212 @default.
- W1925722892 cites W4252217633 @default.
- W1925722892 doi "https://doi.org/10.1002/eji.201344322" @default.
- W1925722892 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4165787" @default.
- W1925722892 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24975032" @default.
- W1925722892 hasPublicationYear "2014" @default.
- W1925722892 type Work @default.
- W1925722892 sameAs 1925722892 @default.
- W1925722892 citedByCount "4" @default.
- W1925722892 countsByYear W19257228922015 @default.
- W1925722892 countsByYear W19257228922018 @default.
- W1925722892 countsByYear W19257228922022 @default.
- W1925722892 crossrefType "journal-article" @default.
- W1925722892 hasAuthorship W1925722892A5015837535 @default.
- W1925722892 hasAuthorship W1925722892A5021390331 @default.
- W1925722892 hasAuthorship W1925722892A5021685638 @default.
- W1925722892 hasAuthorship W1925722892A5040688856 @default.
- W1925722892 hasAuthorship W1925722892A5042362492 @default.
- W1925722892 hasAuthorship W1925722892A5046660376 @default.
- W1925722892 hasAuthorship W1925722892A5049928231 @default.
- W1925722892 hasAuthorship W1925722892A5084604266 @default.
- W1925722892 hasBestOaLocation W19257228922 @default.