Matches in SemOpenAlex for { <https://semopenalex.org/work/W1925798918> ?p ?o ?g. }
Showing items 1 to 62 of
62
with 100 items per page.
- W1925798918 endingPage "5" @default.
- W1925798918 startingPage "10" @default.
- W1925798918 abstract "Transitional cell carcinoma of the urothelium is a chemosensitive tumor, and combination chemotherapy can provide not only palliation but a modest survival advantage in patients with advanced disease. While the four-drug regimen methotrexate/vinblastine/doxorubicin/cisplatin remains the standard combination therapy, its toxicity can be formidable. The overall response rate in phase III trials with this combination is in the 35% to 45% range, with a median survival duration in treated patients of only 12 months. Although attempts to decrease the toxicity of the regimen with the addition of hematopoietic growth factors have been successful, attempts to increase its efficacy by dose escalation have not. This has prompted a search for new active agents that can be incorporated into alternative combination regimens. Recently, activity has been noted for several drugs (including gallium nitrate, ifosfamide, and gemcitabine). In untreated patients, paclitaxel has demonstrated significant activity and is certainly among the most active single agents in the treatment of advanced bladder cancer. Studies incorporating these new agents into novel combination regimens are ongoing, with the goal of providing a regimen that has superior efficacy in advanced disease and, ultimately, in earlier stages of disease with curative intent." @default.
- W1925798918 created "2016-06-24" @default.
- W1925798918 creator A5040850986 @default.
- W1925798918 date "1995-04-01" @default.
- W1925798918 modified "2023-09-26" @default.
- W1925798918 title "Palliative chemotherapy in advanced bladder cancer." @default.
- W1925798918 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7537896" @default.
- W1925798918 hasPublicationYear "1995" @default.
- W1925798918 type Work @default.
- W1925798918 sameAs 1925798918 @default.
- W1925798918 citedByCount "3" @default.
- W1925798918 crossrefType "journal-article" @default.
- W1925798918 hasAuthorship W1925798918A5040850986 @default.
- W1925798918 hasConcept C121608353 @default.
- W1925798918 hasConcept C126322002 @default.
- W1925798918 hasConcept C141071460 @default.
- W1925798918 hasConcept C143998085 @default.
- W1925798918 hasConcept C2776694085 @default.
- W1925798918 hasConcept C2777132456 @default.
- W1925798918 hasConcept C2777506904 @default.
- W1925798918 hasConcept C2778065480 @default.
- W1925798918 hasConcept C2778239845 @default.
- W1925798918 hasConcept C2780258809 @default.
- W1925798918 hasConcept C2780352672 @default.
- W1925798918 hasConcept C2781413609 @default.
- W1925798918 hasConcept C3019864225 @default.
- W1925798918 hasConcept C71924100 @default.
- W1925798918 hasConceptScore W1925798918C121608353 @default.
- W1925798918 hasConceptScore W1925798918C126322002 @default.
- W1925798918 hasConceptScore W1925798918C141071460 @default.
- W1925798918 hasConceptScore W1925798918C143998085 @default.
- W1925798918 hasConceptScore W1925798918C2776694085 @default.
- W1925798918 hasConceptScore W1925798918C2777132456 @default.
- W1925798918 hasConceptScore W1925798918C2777506904 @default.
- W1925798918 hasConceptScore W1925798918C2778065480 @default.
- W1925798918 hasConceptScore W1925798918C2778239845 @default.
- W1925798918 hasConceptScore W1925798918C2780258809 @default.
- W1925798918 hasConceptScore W1925798918C2780352672 @default.
- W1925798918 hasConceptScore W1925798918C2781413609 @default.
- W1925798918 hasConceptScore W1925798918C3019864225 @default.
- W1925798918 hasConceptScore W1925798918C71924100 @default.
- W1925798918 hasIssue "2 Suppl 3" @default.
- W1925798918 hasLocation W19257989181 @default.
- W1925798918 hasOpenAccess W1925798918 @default.
- W1925798918 hasPrimaryLocation W19257989181 @default.
- W1925798918 hasRelatedWork W158918838 @default.
- W1925798918 hasRelatedWork W1925798918 @default.
- W1925798918 hasRelatedWork W1965593755 @default.
- W1925798918 hasRelatedWork W2000416122 @default.
- W1925798918 hasRelatedWork W2007665175 @default.
- W1925798918 hasRelatedWork W2091255480 @default.
- W1925798918 hasRelatedWork W2123970447 @default.
- W1925798918 hasRelatedWork W2156133317 @default.
- W1925798918 hasRelatedWork W2316798262 @default.
- W1925798918 hasRelatedWork W335570002 @default.
- W1925798918 hasVolume "22" @default.
- W1925798918 isParatext "false" @default.
- W1925798918 isRetracted "false" @default.
- W1925798918 magId "1925798918" @default.
- W1925798918 workType "article" @default.