Matches in SemOpenAlex for { <https://semopenalex.org/work/W192595281> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W192595281 endingPage "52" @default.
- W192595281 startingPage "440" @default.
- W192595281 abstract "Despite its dramatic decline in incidence in developed countries, gastric cancer is a major public health issue in the world. Accumulating evidence for considering H. pylori as a causal factor for gastric cancer comes from recent epidemiologic studies, the advent of an animal model of gastric cancer and from new insights into the biological mechanisms for gastric carcinogenesis. The stomach cancer risk for people infected with H. pylori is rather low, inferior to 1%. It depends on genotypic polymorphisms of both the bacterium and the host. Environmental risk factors such as smoking habits, salt intake, and the amount of antioxidants in diet may interfere with H. pylori and modify the cancer risk. There is no definite clinical evidence of the benefit of eradication on cancer risk in humans due to the lack of randomized controlled studies in large populations. The occurrence of gastric adenocarcinomas in patients after complete remission of gastric MALT lymphoma induced by H. pylori eradication suggests also the limits of the preventive strategy against gastric cancer. Furthermore, the effectiveness of eradication to reverse precancerous gastric lesions such as severe atrophy and intestinal metaplasia is questionable. For many reasons discussed in our review, population-based screening and routine eradication of H. pylori infection seem to be an unrealistic goal and cannot be recommended in France. By waiting for effective anti-H. pylori vaccine, public health measures such as dietary modification should be promoted to further decrease the gastric cancer incidence. On the individual basis the specialist has a role in the diagnosis of gastric precancerous lesions by endoscopy and also in the prevention of gastric cancer by selecting indications for H. pylori therapy." @default.
- W192595281 created "2016-06-24" @default.
- W192595281 creator A5010310707 @default.
- W192595281 date "2003-03-01" @default.
- W192595281 modified "2023-10-06" @default.
- W192595281 title "[Could Helicobacter pylori treatment reduce stomach cancer risk?]." @default.
- W192595281 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12700501" @default.
- W192595281 hasPublicationYear "2003" @default.
- W192595281 type Work @default.
- W192595281 sameAs 192595281 @default.
- W192595281 citedByCount "8" @default.
- W192595281 countsByYear W1925952812019 @default.
- W192595281 crossrefType "journal-article" @default.
- W192595281 hasAuthorship W192595281A5010310707 @default.
- W192595281 hasConcept C120665830 @default.
- W192595281 hasConcept C121332964 @default.
- W192595281 hasConcept C121608353 @default.
- W192595281 hasConcept C126322002 @default.
- W192595281 hasConcept C143998085 @default.
- W192595281 hasConcept C2776409635 @default.
- W192595281 hasConcept C2776497702 @default.
- W192595281 hasConcept C2778677798 @default.
- W192595281 hasConcept C2779422922 @default.
- W192595281 hasConcept C2779454504 @default.
- W192595281 hasConcept C2780234812 @default.
- W192595281 hasConcept C2780342937 @default.
- W192595281 hasConcept C2908647359 @default.
- W192595281 hasConcept C61511704 @default.
- W192595281 hasConcept C71924100 @default.
- W192595281 hasConcept C90924648 @default.
- W192595281 hasConcept C99454951 @default.
- W192595281 hasConceptScore W192595281C120665830 @default.
- W192595281 hasConceptScore W192595281C121332964 @default.
- W192595281 hasConceptScore W192595281C121608353 @default.
- W192595281 hasConceptScore W192595281C126322002 @default.
- W192595281 hasConceptScore W192595281C143998085 @default.
- W192595281 hasConceptScore W192595281C2776409635 @default.
- W192595281 hasConceptScore W192595281C2776497702 @default.
- W192595281 hasConceptScore W192595281C2778677798 @default.
- W192595281 hasConceptScore W192595281C2779422922 @default.
- W192595281 hasConceptScore W192595281C2779454504 @default.
- W192595281 hasConceptScore W192595281C2780234812 @default.
- W192595281 hasConceptScore W192595281C2780342937 @default.
- W192595281 hasConceptScore W192595281C2908647359 @default.
- W192595281 hasConceptScore W192595281C61511704 @default.
- W192595281 hasConceptScore W192595281C71924100 @default.
- W192595281 hasConceptScore W192595281C90924648 @default.
- W192595281 hasConceptScore W192595281C99454951 @default.
- W192595281 hasIssue "3 Pt 2" @default.
- W192595281 hasLocation W1925952811 @default.
- W192595281 hasOpenAccess W192595281 @default.
- W192595281 hasPrimaryLocation W1925952811 @default.
- W192595281 hasRelatedWork W1958445873 @default.
- W192595281 hasRelatedWork W1969107480 @default.
- W192595281 hasRelatedWork W2026860891 @default.
- W192595281 hasRelatedWork W2087809170 @default.
- W192595281 hasRelatedWork W2153899659 @default.
- W192595281 hasRelatedWork W2241244230 @default.
- W192595281 hasRelatedWork W2398104003 @default.
- W192595281 hasRelatedWork W2711565797 @default.
- W192595281 hasRelatedWork W2742765655 @default.
- W192595281 hasRelatedWork W3148183718 @default.
- W192595281 hasVolume "27" @default.
- W192595281 isParatext "false" @default.
- W192595281 isRetracted "false" @default.
- W192595281 magId "192595281" @default.
- W192595281 workType "article" @default.