FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1926095499> ?p ?o ?g. }

• W1926095499 endingPage "E605" @default.
• W1926095499 startingPage "E600" @default.
• W1926095499 abstract "Excessive fat turnover and oxidation might cause the insulin resistance of carbohydrate metabolism in obese humans. We studied the response of free fatty acid (FFA) metabolism in lean and obese volunteers to sequential insulin infusions of 4, 8, 25, and 400 mU.m-2.min-1. The insulin dose-response curves for suppression of FFA concentration, FFA turnover ([1-14C]palmitate), and lipolysis ([2H5]glycerol) were shifted to the right in the obese subjects (insulin concentrations that produced a half-maximal response, lean vs. obese: 103 +/- 21 vs. 273 +/- 41, 96 +/- 11 vs. 264 +/- 44, and 101 +/- 23 vs. 266 +/- 44 pM, all P < 0.05), consistent with insulin resistance of FFA metabolism in obesity. After the overnight fast, FFA turnover per fat mass was decreased in obese subjects (37 +/- 4 vs. 20 +/- 3 mumol.kg fat mass-1.min-1, P < 0.01) as the result of suppression of lipolysis by the hyperinsulinemia of obesity and an increased fractional reesterification of FFA before leaving the adipocyte (primary FFA reesterification; 0.14 +/- 0.03 vs. 0.35 +/- 0.06, P < 0.05). Nevertheless, FFA turnover per fat-free mass (FFM) was also greater in the obese volunteers (8.5 +/- 0.7 vs. 11.0 +/- 1.0 mumol.kg FFM-1.min-1, P < 0.05) but only as the result of increased reesterification of intravascular FFA (secondary reesterification; 1.8 +/- 0.5 vs. 4.8 +/- 1.1 mumol.kg FFM-1.min-1, P < 0.01), since FFA oxidation was the same in the two groups throughout the insulin dose-response curve.(ABSTRACT TRUNCATED AT 250 WORDS)" @default.
• W1926095499 created "2016-06-24" @default.
• W1926095499 creator A5013183748 @default.
• W1926095499 creator A5026738636 @default.
• W1926095499 creator A5076584809 @default.
• W1926095499 date "1994-04-01" @default.
• W1926095499 modified "2023-10-03" @default.
• W1926095499 title "Fat metabolism in human obesity" @default.
• W1926095499 cites W1981456793 @default.
• W1926095499 cites W1984260164 @default.
• W1926095499 cites W1987074453 @default.
• W1926095499 cites W1993480864 @default.
• W1926095499 cites W1994543634 @default.
• W1926095499 cites W1999489587 @default.
• W1926095499 cites W2002888717 @default.
• W1926095499 cites W2003950656 @default.
• W1926095499 cites W2012898950 @default.
• W1926095499 cites W2016777958 @default.
• W1926095499 cites W2037716180 @default.
• W1926095499 cites W2039242258 @default.
• W1926095499 cites W2040860939 @default.
• W1926095499 cites W2051976607 @default.
• W1926095499 cites W2062388756 @default.
• W1926095499 cites W2081892985 @default.
• W1926095499 cites W2082077211 @default.
• W1926095499 cites W2089838722 @default.
• W1926095499 cites W2130200187 @default.
• W1926095499 cites W2131501155 @default.
• W1926095499 cites W2156794681 @default.
• W1926095499 cites W2166716973 @default.
• W1926095499 cites W2168017449 @default.
• W1926095499 cites W2319176243 @default.
• W1926095499 cites W2319231450 @default.
• W1926095499 cites W2335145280 @default.
• W1926095499 cites W3023173633 @default.
• W1926095499 cites W4243841175 @default.
• W1926095499 doi "https://doi.org/10.1152/ajpendo.1994.266.4.e600" @default.
• W1926095499 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8178981" @default.
• W1926095499 hasPublicationYear "1994" @default.
• W1926095499 type Work @default.
• W1926095499 sameAs 1926095499 @default.
• W1926095499 citedByCount "70" @default.
• W1926095499 countsByYear W19260954992012 @default.
• W1926095499 countsByYear W19260954992013 @default.
• W1926095499 countsByYear W19260954992014 @default.
• W1926095499 countsByYear W19260954992015 @default.
• W1926095499 countsByYear W19260954992016 @default.
• W1926095499 countsByYear W19260954992017 @default.
• W1926095499 countsByYear W19260954992020 @default.
• W1926095499 countsByYear W19260954992021 @default.
• W1926095499 countsByYear W19260954992022 @default.
• W1926095499 countsByYear W19260954992023 @default.
• W1926095499 crossrefType "journal-article" @default.
• W1926095499 hasAuthorship W1926095499A5013183748 @default.
• W1926095499 hasAuthorship W1926095499A5026738636 @default.
• W1926095499 hasAuthorship W1926095499A5076584809 @default.
• W1926095499 hasConcept C126322002 @default.
• W1926095499 hasConcept C134018914 @default.
• W1926095499 hasConcept C140985366 @default.
• W1926095499 hasConcept C17093226 @default.
• W1926095499 hasConcept C171089720 @default.
• W1926095499 hasConcept C185592680 @default.
• W1926095499 hasConcept C2777391703 @default.
• W1926095499 hasConcept C2778808658 @default.
• W1926095499 hasConcept C2779306644 @default.
• W1926095499 hasConcept C2780352109 @default.
• W1926095499 hasConcept C2780988686 @default.
• W1926095499 hasConcept C511355011 @default.
• W1926095499 hasConcept C543025807 @default.
• W1926095499 hasConcept C55493867 @default.
• W1926095499 hasConcept C62231903 @default.
• W1926095499 hasConcept C71924100 @default.
• W1926095499 hasConceptScore W1926095499C126322002 @default.
• W1926095499 hasConceptScore W1926095499C134018914 @default.
• W1926095499 hasConceptScore W1926095499C140985366 @default.
• W1926095499 hasConceptScore W1926095499C17093226 @default.
• W1926095499 hasConceptScore W1926095499C171089720 @default.
• W1926095499 hasConceptScore W1926095499C185592680 @default.
• W1926095499 hasConceptScore W1926095499C2777391703 @default.
• W1926095499 hasConceptScore W1926095499C2778808658 @default.
• W1926095499 hasConceptScore W1926095499C2779306644 @default.
• W1926095499 hasConceptScore W1926095499C2780352109 @default.
• W1926095499 hasConceptScore W1926095499C2780988686 @default.
• W1926095499 hasConceptScore W1926095499C511355011 @default.
• W1926095499 hasConceptScore W1926095499C543025807 @default.
• W1926095499 hasConceptScore W1926095499C55493867 @default.
• W1926095499 hasConceptScore W1926095499C62231903 @default.
• W1926095499 hasConceptScore W1926095499C71924100 @default.
• W1926095499 hasIssue "4" @default.
• W1926095499 hasLocation W19260954991 @default.
• W1926095499 hasLocation W19260954992 @default.
• W1926095499 hasOpenAccess W1926095499 @default.
• W1926095499 hasPrimaryLocation W19260954991 @default.
• W1926095499 hasRelatedWork W1957106181 @default.
• W1926095499 hasRelatedWork W1974742129 @default.
• W1926095499 hasRelatedWork W2044897248 @default.
• W1926095499 hasRelatedWork W2063441939 @default.
• W1926095499 hasRelatedWork W2094672900 @default.

• next