Matches in SemOpenAlex for { <https://semopenalex.org/work/W1926258489> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W1926258489 endingPage "3221" @default.
- W1926258489 startingPage "3219" @default.
- W1926258489 abstract "There are several experimental contexts in which it is important to identify DNA integration sites, such as insertional mutagenesis screens, gene and enhancer trap applications, and gene therapy. We previously developed an assay to identify millions of integrations in multiplexed barcoded samples at base-pair resolution. The sheer amount of data produced by this approach makes the mapping of individual sites non-trivial without bioinformatics support. This article presents the Genomic Integration Site Tracker (GeIST), a command-line pipeline designed to map the integration sites produced by this assay and identify the samples from which they came. GeIST version 2.1.0, a more adaptable version of our original pipeline, can identify integrations of murine leukemia virus, adeno-associated virus, Tol2 transposons or Ac/Ds transposons, and can be adapted for other inserted elements. It has been tested on experimental data for each of these delivery vectors and fine-tuned to account for sequencing and cloning artifacts.GeIST uses a combination of Bash shell scripting and Perl. GeIST is available at http://research.nhgri.nih.gov/software/GeIST/.burgess@mail.nih.gov." @default.
- W1926258489 created "2016-06-24" @default.
- W1926258489 creator A5021958635 @default.
- W1926258489 creator A5087555842 @default.
- W1926258489 date "2015-06-06" @default.
- W1926258489 modified "2023-10-03" @default.
- W1926258489 title "GeIST: a pipeline for mapping integrated DNA elements" @default.
- W1926258489 cites W1637867377 @default.
- W1926258489 cites W1884756073 @default.
- W1926258489 cites W1971277282 @default.
- W1926258489 cites W1989322815 @default.
- W1926258489 cites W1998512131 @default.
- W1926258489 cites W2008052698 @default.
- W1926258489 cites W2014894652 @default.
- W1926258489 cites W2033141278 @default.
- W1926258489 cites W2034118113 @default.
- W1926258489 cites W2036897871 @default.
- W1926258489 cites W2108234281 @default.
- W1926258489 cites W2124985265 @default.
- W1926258489 cites W2128016314 @default.
- W1926258489 cites W2133112334 @default.
- W1926258489 cites W2141735759 @default.
- W1926258489 cites W2147841875 @default.
- W1926258489 cites W2159686532 @default.
- W1926258489 cites W2165926588 @default.
- W1926258489 cites W4323238558 @default.
- W1926258489 doi "https://doi.org/10.1093/bioinformatics/btv350" @default.
- W1926258489 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4592334" @default.
- W1926258489 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26049161" @default.
- W1926258489 hasPublicationYear "2015" @default.
- W1926258489 type Work @default.
- W1926258489 sameAs 1926258489 @default.
- W1926258489 citedByCount "7" @default.
- W1926258489 countsByYear W19262584892015 @default.
- W1926258489 countsByYear W19262584892016 @default.
- W1926258489 countsByYear W19262584892017 @default.
- W1926258489 countsByYear W19262584892021 @default.
- W1926258489 countsByYear W19262584892023 @default.
- W1926258489 crossrefType "journal-article" @default.
- W1926258489 hasAuthorship W1926258489A5021958635 @default.
- W1926258489 hasAuthorship W1926258489A5087555842 @default.
- W1926258489 hasBestOaLocation W19262584891 @default.
- W1926258489 hasConcept C104317684 @default.
- W1926258489 hasConcept C107635520 @default.
- W1926258489 hasConcept C141231307 @default.
- W1926258489 hasConcept C151810110 @default.
- W1926258489 hasConcept C199360897 @default.
- W1926258489 hasConcept C41008148 @default.
- W1926258489 hasConcept C43521106 @default.
- W1926258489 hasConcept C54355233 @default.
- W1926258489 hasConcept C70721500 @default.
- W1926258489 hasConcept C86803240 @default.
- W1926258489 hasConceptScore W1926258489C104317684 @default.
- W1926258489 hasConceptScore W1926258489C107635520 @default.
- W1926258489 hasConceptScore W1926258489C141231307 @default.
- W1926258489 hasConceptScore W1926258489C151810110 @default.
- W1926258489 hasConceptScore W1926258489C199360897 @default.
- W1926258489 hasConceptScore W1926258489C41008148 @default.
- W1926258489 hasConceptScore W1926258489C43521106 @default.
- W1926258489 hasConceptScore W1926258489C54355233 @default.
- W1926258489 hasConceptScore W1926258489C70721500 @default.
- W1926258489 hasConceptScore W1926258489C86803240 @default.
- W1926258489 hasIssue "19" @default.
- W1926258489 hasLocation W19262584891 @default.
- W1926258489 hasLocation W19262584892 @default.
- W1926258489 hasLocation W19262584893 @default.
- W1926258489 hasLocation W19262584894 @default.
- W1926258489 hasOpenAccess W1926258489 @default.
- W1926258489 hasPrimaryLocation W19262584891 @default.
- W1926258489 hasRelatedWork W1828691184 @default.
- W1926258489 hasRelatedWork W1991523530 @default.
- W1926258489 hasRelatedWork W2002128513 @default.
- W1926258489 hasRelatedWork W2020824267 @default.
- W1926258489 hasRelatedWork W2031436818 @default.
- W1926258489 hasRelatedWork W2057739827 @default.
- W1926258489 hasRelatedWork W2075354549 @default.
- W1926258489 hasRelatedWork W2123812634 @default.
- W1926258489 hasRelatedWork W2992516105 @default.
- W1926258489 hasRelatedWork W2092874662 @default.
- W1926258489 hasVolume "31" @default.
- W1926258489 isParatext "false" @default.
- W1926258489 isRetracted "false" @default.
- W1926258489 magId "1926258489" @default.
- W1926258489 workType "article" @default.