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• W1927429241 startingPage "2882" @default.
• W1927429241 abstract "Endogenous opioid peptides within the nucleus accumbens, a forebrain site critical for the regulation of reward-related behavior, are believed to play an important role in the control of appetite. In particular, this system is thought to mediate the hedonic aspects of food intake, governing the positive emotional response to highly palatable food such as fat and sugar. Previous work has shown that intra-accumbens administration of the mu-opioid agonist D-Ala2,Nme-Phe4,Glyol5-enkephalin (DAMGO) markedly increases food intake and preferentially enhances the intake of palatable foods such as fat, sucrose, and salt. Using information from recently performed c-fos mapping experiments, we sought to explore the involvement of structures efferent to the nucleus accumbens in this feeding response. Free-feeding rats with dual sets of bilateral cannulas aimed at the nucleus accumbens and one of several output structures were infused with DAMGO (0, 0.25 microg/0.5 microl) in the accumbens, and fat intake was measured over a 2 hr period. Concurrent temporary inactivation with the GABA(A) agonist muscimol (5-20 ng/0.25 microl) of the dorsomedial hypothalamic nucleus, lateral hypothalamus, ventral tegmental area, or the intermediate region of the nucleus of the solitary tract blocked the robust increase in fat intake induced by intra-accumbens DAMGO at doses of muscimol that did not affect general motor activity. Muscimol alone also inhibited and augmented baseline fat intake in the lateral and dorsomedial hypothalamic nuclei, respectively. These results suggest that intake of energy-dense palatable food is controlled by activity in a neural network linking ventral striatal opioids with diencephalic and brainstem structures." @default.
• W1927429241 created "2016-06-24" @default.
• W1927429241 creator A5015308276 @default.
• W1927429241 creator A5018633729 @default.
• W1927429241 creator A5087511851 @default.
• W1927429241 date "2003-04-01" @default.
• W1927429241 modified "2023-10-06" @default.
• W1927429241 title "Nucleus accumbens mu-opioids regulate intake of a high-fat diet via activation of a distributed brain network." @default.
• W1927429241 cites W1552874515 @default.
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• W1927429241 cites W1967002073 @default.
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• W1927429241 cites W1974934764 @default.
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• W1927429241 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6742055" @default.
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