Matches in SemOpenAlex for { <https://semopenalex.org/work/W1927631036> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W1927631036 endingPage "107" @default.
- W1927631036 startingPage "97" @default.
- W1927631036 abstract "The addition of glutamate to the bathing medium increased the average firing rate of cerebellar rat Purkinje cells in vitro. At concentrations lower than 10−6 M, there was no deviation from controls in the firing pattern or rate that was detectable. At 10−3 M glutamate, the amplitude of the action potentials was gradually decreased until all activity was abolished. The action of glutamate was rapid in onset and reversible. Glycine produced sustained depression of firing at concentrations higher than 10−3 M. This inhibition was strychnine-insensitive and considered nonspecific. Strychnine, on the other hand, exerted an excitatory influence on Purkinje cells when applied at low concentrations (10−8 to 10−6 M). The firing became more irregular and complex discharges appeared. Higher concentrations of strychnine (>10−5 M) inhibited the spontaneous activity. The effect of strychnine was partly reversible. The data suggest that low concentrations of strychnine lower the threshold for inputs at excitatory as well as inhibitory synapses." @default.
- W1927631036 created "2016-06-24" @default.
- W1927631036 creator A5086901860 @default.
- W1927631036 date "1976-03-01" @default.
- W1927631036 modified "2023-09-25" @default.
- W1927631036 title "Spontaneous bioelectric activity of cultured purkinje cells during exposure to glutamate, glycine, and strychnine" @default.
- W1927631036 cites W166813605 @default.
- W1927631036 cites W1964683490 @default.
- W1927631036 cites W1967870068 @default.
- W1927631036 cites W1978921128 @default.
- W1927631036 cites W2001485933 @default.
- W1927631036 cites W2005584845 @default.
- W1927631036 cites W2007348714 @default.
- W1927631036 cites W2011307168 @default.
- W1927631036 cites W2025051579 @default.
- W1927631036 cites W2031863061 @default.
- W1927631036 cites W2034347006 @default.
- W1927631036 cites W2038712978 @default.
- W1927631036 cites W2044713185 @default.
- W1927631036 cites W2059505091 @default.
- W1927631036 cites W2061677650 @default.
- W1927631036 cites W2067203970 @default.
- W1927631036 cites W2069097002 @default.
- W1927631036 cites W2070196483 @default.
- W1927631036 cites W2077209395 @default.
- W1927631036 cites W2085139537 @default.
- W1927631036 cites W2150200613 @default.
- W1927631036 cites W2185680434 @default.
- W1927631036 cites W2206678636 @default.
- W1927631036 cites W939271059 @default.
- W1927631036 doi "https://doi.org/10.1002/neu.480070203" @default.
- W1927631036 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/944238" @default.
- W1927631036 hasPublicationYear "1976" @default.
- W1927631036 type Work @default.
- W1927631036 sameAs 1927631036 @default.
- W1927631036 citedByCount "26" @default.
- W1927631036 countsByYear W19276310362020 @default.
- W1927631036 crossrefType "journal-article" @default.
- W1927631036 hasAuthorship W1927631036A5086901860 @default.
- W1927631036 hasConcept C112592302 @default.
- W1927631036 hasConcept C12554922 @default.
- W1927631036 hasConcept C169760540 @default.
- W1927631036 hasConcept C170493617 @default.
- W1927631036 hasConcept C17077164 @default.
- W1927631036 hasConcept C185263204 @default.
- W1927631036 hasConcept C185592680 @default.
- W1927631036 hasConcept C2777725853 @default.
- W1927631036 hasConcept C2777756961 @default.
- W1927631036 hasConcept C2779652256 @default.
- W1927631036 hasConcept C35599011 @default.
- W1927631036 hasConcept C515207424 @default.
- W1927631036 hasConcept C55493867 @default.
- W1927631036 hasConcept C61174792 @default.
- W1927631036 hasConcept C86803240 @default.
- W1927631036 hasConcept C98274493 @default.
- W1927631036 hasConceptScore W1927631036C112592302 @default.
- W1927631036 hasConceptScore W1927631036C12554922 @default.
- W1927631036 hasConceptScore W1927631036C169760540 @default.
- W1927631036 hasConceptScore W1927631036C170493617 @default.
- W1927631036 hasConceptScore W1927631036C17077164 @default.
- W1927631036 hasConceptScore W1927631036C185263204 @default.
- W1927631036 hasConceptScore W1927631036C185592680 @default.
- W1927631036 hasConceptScore W1927631036C2777725853 @default.
- W1927631036 hasConceptScore W1927631036C2777756961 @default.
- W1927631036 hasConceptScore W1927631036C2779652256 @default.
- W1927631036 hasConceptScore W1927631036C35599011 @default.
- W1927631036 hasConceptScore W1927631036C515207424 @default.
- W1927631036 hasConceptScore W1927631036C55493867 @default.
- W1927631036 hasConceptScore W1927631036C61174792 @default.
- W1927631036 hasConceptScore W1927631036C86803240 @default.
- W1927631036 hasConceptScore W1927631036C98274493 @default.
- W1927631036 hasIssue "2" @default.
- W1927631036 hasLocation W19276310361 @default.
- W1927631036 hasLocation W19276310362 @default.
- W1927631036 hasOpenAccess W1927631036 @default.
- W1927631036 hasPrimaryLocation W19276310361 @default.
- W1927631036 hasRelatedWork W1927631036 @default.
- W1927631036 hasRelatedWork W1982517570 @default.
- W1927631036 hasRelatedWork W2021958520 @default.
- W1927631036 hasRelatedWork W2025698938 @default.
- W1927631036 hasRelatedWork W2160843619 @default.
- W1927631036 hasRelatedWork W2411662560 @default.
- W1927631036 hasRelatedWork W2466510963 @default.
- W1927631036 hasRelatedWork W3086570168 @default.
- W1927631036 hasRelatedWork W3117314273 @default.
- W1927631036 hasRelatedWork W982011816 @default.
- W1927631036 hasVolume "7" @default.
- W1927631036 isParatext "false" @default.
- W1927631036 isRetracted "false" @default.
- W1927631036 magId "1927631036" @default.
- W1927631036 workType "article" @default.