FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1928291205> ?p ?o ?g. }

• W1928291205 endingPage "139" @default.
• W1928291205 startingPage "130" @default.
• W1928291205 abstract "Donalisio, C., Barbero, R., Cuniberti, B., Vercelli, C., Casalone, M., Re, G. Effects of flunixin meglumine and ketoprofen on mediator production in ex vivo and in vitro models of inflammation in healthy dairy cows. J. vet. Pharmacol. Therap. 36 , 130–139. In this study, ex vivo assays were carried out in dairy cows to evaluate the anti‐inflammatory effects of two nonsteroidal anti‐inflammatory drugs: ketoprofen (KETO) and flunixin meglumine (FM). Twelve healthy Holstein dairy cattle were randomly allocated to two groups ( n =6): group 1 received FM and group 2 received KETO at recommended therapeutic dosages. The anti‐inflammatory effects of both drugs were determined by measuring the production of coagulation‐induced thromboxane B 2 (TXB 2 ), lipopolysaccharides (LPS) (10 μg/mL)‐induced prostaglandin E 2 (PGE 2 ), and calcium ionophore (60 μ m )‐induced leukotrien B 4 (LTB 4 ). Cytokine production was assessed by measuring tumor necrosis factor‐α (TNF‐α), interferon‐γ (IFN‐γ) and interleukin‐8 (CXCL8) concentrations after incubation in the presence of 10 μg/mL LPS. The IC 50 of FM and KETO was determined in vitro by determining the concentration of TXB 2 and PGE 2 in the presence of scalar drug concentrations (10 −9 –10 −3 m ). Both FM and KETO inhibited the two COX isoforms in vitro, but showed a preference for COX‐1. FM and KETO showed similar anti‐inflammatory effects in the cow." @default.
• W1928291205 created "2016-06-24" @default.
• W1928291205 creator A5017829476 @default.
• W1928291205 creator A5024180482 @default.
• W1928291205 creator A5028272132 @default.
• W1928291205 creator A5053154367 @default.
• W1928291205 creator A5063486305 @default.
• W1928291205 creator A5068736681 @default.
• W1928291205 date "2012-06-24" @default.
• W1928291205 modified "2023-10-15" @default.
• W1928291205 title "Effects of flunixin meglumine and ketoprofen on mediator production in<i>ex vivo</i>and<i>in vitro</i>models of inflammation in healthy dairy cows" @default.
• W1928291205 cites W1521499119 @default.
• W1928291205 cites W183558380 @default.
• W1928291205 cites W1974508755 @default.
• W1928291205 cites W1981188464 @default.
• W1928291205 cites W1995082781 @default.
• W1928291205 cites W1999700795 @default.
• W1928291205 cites W2000547109 @default.
• W1928291205 cites W2005145329 @default.
• W1928291205 cites W2005400238 @default.
• W1928291205 cites W2007747723 @default.
• W1928291205 cites W2008838291 @default.
• W1928291205 cites W2009228494 @default.
• W1928291205 cites W2016006095 @default.
• W1928291205 cites W2018905034 @default.
• W1928291205 cites W2019831549 @default.
• W1928291205 cites W2029507589 @default.
• W1928291205 cites W2030887834 @default.
• W1928291205 cites W2032569263 @default.
• W1928291205 cites W2035346951 @default.
• W1928291205 cites W2048220307 @default.
• W1928291205 cites W2052199209 @default.
• W1928291205 cites W2052996638 @default.
• W1928291205 cites W2058148231 @default.
• W1928291205 cites W2061301377 @default.
• W1928291205 cites W2065775710 @default.
• W1928291205 cites W2068999043 @default.
• W1928291205 cites W2069452070 @default.
• W1928291205 cites W2073110223 @default.
• W1928291205 cites W2073584153 @default.
• W1928291205 cites W2076974145 @default.
• W1928291205 cites W2083729333 @default.
• W1928291205 cites W2106515853 @default.
• W1928291205 cites W2125918623 @default.
• W1928291205 cites W2134229943 @default.
• W1928291205 cites W2160232038 @default.
• W1928291205 cites W2176223876 @default.
• W1928291205 cites W2391191430 @default.
• W1928291205 doi "https://doi.org/10.1111/j.1365-2885.2012.01396.x" @default.
• W1928291205 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22724509" @default.
• W1928291205 hasPublicationYear "2012" @default.
• W1928291205 type Work @default.
• W1928291205 sameAs 1928291205 @default.
• W1928291205 citedByCount "16" @default.
• W1928291205 countsByYear W19282912052013 @default.
• W1928291205 countsByYear W19282912052014 @default.
• W1928291205 countsByYear W19282912052015 @default.
• W1928291205 countsByYear W19282912052016 @default.
• W1928291205 countsByYear W19282912052017 @default.
• W1928291205 countsByYear W19282912052018 @default.
• W1928291205 countsByYear W19282912052021 @default.
• W1928291205 countsByYear W19282912052023 @default.
• W1928291205 crossrefType "journal-article" @default.
• W1928291205 hasAuthorship W1928291205A5017829476 @default.
• W1928291205 hasAuthorship W1928291205A5024180482 @default.
• W1928291205 hasAuthorship W1928291205A5028272132 @default.
• W1928291205 hasAuthorship W1928291205A5053154367 @default.
• W1928291205 hasAuthorship W1928291205A5063486305 @default.
• W1928291205 hasAuthorship W1928291205A5068736681 @default.
• W1928291205 hasBestOaLocation W19282912052 @default.
• W1928291205 hasConcept C126322002 @default.
• W1928291205 hasConcept C150903083 @default.
• W1928291205 hasConcept C17991360 @default.
• W1928291205 hasConcept C185592680 @default.
• W1928291205 hasConcept C202751555 @default.
• W1928291205 hasConcept C203014093 @default.
• W1928291205 hasConcept C207001950 @default.
• W1928291205 hasConcept C26291073 @default.
• W1928291205 hasConcept C2776785769 @default.
• W1928291205 hasConcept C2777956040 @default.
• W1928291205 hasConcept C2778690821 @default.
• W1928291205 hasConcept C2780744026 @default.
• W1928291205 hasConcept C2781080829 @default.
• W1928291205 hasConcept C55493867 @default.
• W1928291205 hasConcept C71924100 @default.
• W1928291205 hasConcept C86803240 @default.
• W1928291205 hasConcept C89560881 @default.
• W1928291205 hasConcept C98274493 @default.
• W1928291205 hasConceptScore W1928291205C126322002 @default.
• W1928291205 hasConceptScore W1928291205C150903083 @default.
• W1928291205 hasConceptScore W1928291205C17991360 @default.
• W1928291205 hasConceptScore W1928291205C185592680 @default.
• W1928291205 hasConceptScore W1928291205C202751555 @default.
• W1928291205 hasConceptScore W1928291205C203014093 @default.
• W1928291205 hasConceptScore W1928291205C207001950 @default.
• W1928291205 hasConceptScore W1928291205C26291073 @default.
• W1928291205 hasConceptScore W1928291205C2776785769 @default.
• W1928291205 hasConceptScore W1928291205C2777956040 @default.

• next