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- W1928374939 abstract "We mapped and sequenced three upstream exons of the chicken c-myb gene and the regions flanking the first coding exon. We found multiple potential binding sites for transcription factors in the 5'-noncoding region, a T-rich stretch of 78 base pairs (bp) (68% T) in the first intron, and four fairly long open reading frames in the antisense direction of the first coding exon and its flanking regions. Three major transcription start sites, contained within a single 11-bp region, were identified by S1 nuclease analysis and primer extension. A sequence comparison of the avian and murine c-myb genes revealed a highly conserved sequence of 124 bp in the 5'-noncoding region. Its location between the putative transcription factor binding sites and the major transcription start sites suggests that it may play an important regulatory role in c-myb expression." @default.
- W1928374939 created "2016-06-24" @default.
- W1928374939 creator A5004351298 @default.
- W1928374939 creator A5078023674 @default.
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- W1928374939 date "1989-02-01" @default.
- W1928374939 modified "2023-09-25" @default.
- W1928374939 title "Structural organization of upstream exons and distribution of transcription start sites in the chicken c-myb gene" @default.
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- W1928374939 doi "https://doi.org/10.1128/mcb.9.2.837-843.1989" @default.
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