FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1929122884> ?p ?o ?g. }

• W1929122884 endingPage "317" @default.
• W1929122884 startingPage "306" @default.
• W1929122884 abstract "Aquaporin-3 (AQP3), is an aquaglyceroporin, that plays a role in cell proliferation, tumorigenesis, and cell migration. This study aimed at evaluating the possible role of AQP3 in nonmelanoma skin cancer (NMSC) pathogenesis through its immunohistochemical expression in skin biopsies of these diseases. One-hundred and thirty cutaneous specimens were studied. These included 60 cases of NMSC and 40 normal skin and 30 psoriasis samples, from age- and gender-matched subjects, as a control group. AQP3 was expressed in 66.7% of basal cell carcinoma (BCC) cases and in 93.3% of squamous cell carcinoma (SCC) cases. Higher AQP3 expression (p = .01), expression percentage (p = .01), and H score (p = .04) were significantly associated with SCC compared to BCC. Normal skin and psoriasis showed significantly higher AQP3 expression (p = .001, p < .001, respectively), expression percentage (p < .001 for both), and H score values (p < .001, p = .001, respectively) compared to NMSC. Higher H score values in BCC were significantly associated with female gender (p = .02) and with nodular lesions (p > .001). Higher H score values in SCC were significantly associated with grade III tumors (p = .04) and AQP3 percentage of expression was significantly correlated with grade III tumors (r = .48, p = .009). In conclusion, AQP3 may play a role in NMSC pathogenesis. This probably occurs through aquaporin-mediated glycerol transport and ATP generation. Its downregulation, observed in the current work, is mostly a result of excessive proliferation. Further studies are needed to investigate the therapeutic effect of its inhibition in NMSC treatment." @default.
• W1929122884 created "2016-06-24" @default.
• W1929122884 creator A5002253998 @default.
• W1929122884 creator A5036547718 @default.
• W1929122884 creator A5047167045 @default.
• W1929122884 creator A5076154362 @default.
• W1929122884 date "2015-06-24" @default.
• W1929122884 modified "2023-09-27" @default.
• W1929122884 title "Evaluation of Aquaporin-3 Role in Nonmelanoma Skin Cancer: An Immunohistochemical Study" @default.
• W1929122884 cites W1599529877 @default.
• W1929122884 cites W1845114139 @default.
• W1929122884 cites W1970841988 @default.
• W1929122884 cites W1975637040 @default.
• W1929122884 cites W1978440987 @default.
• W1929122884 cites W1980367589 @default.
• W1929122884 cites W1984668528 @default.
• W1929122884 cites W1987985147 @default.
• W1929122884 cites W1989207516 @default.
• W1929122884 cites W1989707197 @default.
• W1929122884 cites W1996955051 @default.
• W1929122884 cites W1998907255 @default.
• W1929122884 cites W2008484713 @default.
• W1929122884 cites W2008893599 @default.
• W1929122884 cites W2019525081 @default.
• W1929122884 cites W2030504792 @default.
• W1929122884 cites W2040898244 @default.
• W1929122884 cites W2042226556 @default.
• W1929122884 cites W2049498386 @default.
• W1929122884 cites W2054139430 @default.
• W1929122884 cites W2054208386 @default.
• W1929122884 cites W2056405400 @default.
• W1929122884 cites W2060421943 @default.
• W1929122884 cites W2062097568 @default.
• W1929122884 cites W2065016029 @default.
• W1929122884 cites W2066153715 @default.
• W1929122884 cites W2075104677 @default.
• W1929122884 cites W2094700563 @default.
• W1929122884 cites W2101248660 @default.
• W1929122884 cites W2108858758 @default.
• W1929122884 cites W2113021053 @default.
• W1929122884 cites W2117506568 @default.
• W1929122884 cites W2121313100 @default.
• W1929122884 cites W2128516431 @default.
• W1929122884 cites W2131310812 @default.
• W1929122884 cites W2156657074 @default.
• W1929122884 cites W2168301785 @default.
• W1929122884 cites W4386007350 @default.
• W1929122884 doi "https://doi.org/10.3109/01913123.2015.1022241" @default.
• W1929122884 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26107428" @default.
• W1929122884 hasPublicationYear "2015" @default.
• W1929122884 type Work @default.
• W1929122884 sameAs 1929122884 @default.
• W1929122884 citedByCount "19" @default.
• W1929122884 countsByYear W19291228842015 @default.
• W1929122884 countsByYear W19291228842016 @default.
• W1929122884 countsByYear W19291228842017 @default.
• W1929122884 countsByYear W19291228842018 @default.
• W1929122884 countsByYear W19291228842019 @default.
• W1929122884 countsByYear W19291228842020 @default.
• W1929122884 countsByYear W19291228842021 @default.
• W1929122884 countsByYear W19291228842022 @default.
• W1929122884 countsByYear W19291228842023 @default.
• W1929122884 crossrefType "journal-article" @default.
• W1929122884 hasAuthorship W1929122884A5002253998 @default.
• W1929122884 hasAuthorship W1929122884A5036547718 @default.
• W1929122884 hasAuthorship W1929122884A5047167045 @default.
• W1929122884 hasAuthorship W1929122884A5076154362 @default.
• W1929122884 hasConcept C121608353 @default.
• W1929122884 hasConcept C126322002 @default.
• W1929122884 hasConcept C140737988 @default.
• W1929122884 hasConcept C142724271 @default.
• W1929122884 hasConcept C154280991 @default.
• W1929122884 hasConcept C16005928 @default.
• W1929122884 hasConcept C204232928 @default.
• W1929122884 hasConcept C2777789703 @default.
• W1929122884 hasConcept C2778024521 @default.
• W1929122884 hasConcept C2778804307 @default.
• W1929122884 hasConcept C2779306644 @default.
• W1929122884 hasConcept C2780564577 @default.
• W1929122884 hasConcept C2780942790 @default.
• W1929122884 hasConcept C3019992690 @default.
• W1929122884 hasConcept C42407357 @default.
• W1929122884 hasConcept C555283112 @default.
• W1929122884 hasConcept C71924100 @default.
• W1929122884 hasConcept C90924648 @default.
• W1929122884 hasConceptScore W1929122884C121608353 @default.
• W1929122884 hasConceptScore W1929122884C126322002 @default.
• W1929122884 hasConceptScore W1929122884C140737988 @default.
• W1929122884 hasConceptScore W1929122884C142724271 @default.
• W1929122884 hasConceptScore W1929122884C154280991 @default.
• W1929122884 hasConceptScore W1929122884C16005928 @default.
• W1929122884 hasConceptScore W1929122884C204232928 @default.
• W1929122884 hasConceptScore W1929122884C2777789703 @default.
• W1929122884 hasConceptScore W1929122884C2778024521 @default.
• W1929122884 hasConceptScore W1929122884C2778804307 @default.
• W1929122884 hasConceptScore W1929122884C2779306644 @default.
• W1929122884 hasConceptScore W1929122884C2780564577 @default.
• W1929122884 hasConceptScore W1929122884C2780942790 @default.

• next