FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1930271212> ?p ?o ?g. }

• W1930271212 endingPage "80" @default.
• W1930271212 startingPage "67" @default.
• W1930271212 abstract "Familial adenomatous polyposis (FAP) is a well-known hereditary colorectal cancer-predisposing syndrome. Genetic testing for colorectal cancer risk is now part of standard medical practice, but very little is known about the economic impact of this technology. The aim of this study was to assess, from a healthcare system perspective, the direct costs of two strategies for screening at-risk relatives of FAP patients: clinical screening versus genetic testing for FAP.A systematic review of the literature was carried out. Additional information was gathered from experts in research and clinical laboratories and in hospital departments. A decision tree was constructed to compare per-person and per-family costs of the two strategies for screening at-risk relatives of FAP patients. Sensitivity analysis was performed to assess the stability of the model across the full range of plausible values for all key parameters.According to the decision analysis, with FAP screening starting at puberty, the average screening costs are $3,181 and $2,259 (Canadian dollars), respectively, for the clinical screening and the genetic testing strategies. Genetic screening is cost saving up to a first screening age of 36. Sensitivity analysis shows that the results of the baseline analysis hold across a variety of assumptions concerning the parameter values.The genetic testing strategy is cost saving relative to the clinical screening alternative. Apart from its lower costs, it is associated with many other benefits. Accordingly, under predefined conditions, predictive genetic testing seems to be the optimal screening strategy for FAP." @default.
• W1930271212 created "2016-06-24" @default.
• W1930271212 creator A5010726382 @default.
• W1930271212 creator A5016496681 @default.
• W1930271212 creator A5061257711 @default.
• W1930271212 creator A5070997853 @default.
• W1930271212 date "2002-01-01" @default.
• W1930271212 modified "2023-09-23" @default.
• W1930271212 title "Cost-minimization analysis of genetic testing versus clinical screening of at-risk relatives for familial adenomatous polyposis." @default.
• W1930271212 cites W105212876 @default.
• W1930271212 cites W112327492 @default.
• W1930271212 cites W145661529 @default.
• W1930271212 cites W1541696451 @default.
• W1930271212 cites W1547554587 @default.
• W1930271212 cites W1574399663 @default.
• W1930271212 cites W1968343614 @default.
• W1930271212 cites W1969368411 @default.
• W1930271212 cites W1975993620 @default.
• W1930271212 cites W1979618971 @default.
• W1930271212 cites W1981524857 @default.
• W1930271212 cites W1982793182 @default.
• W1930271212 cites W1995708229 @default.
• W1930271212 cites W1996277769 @default.
• W1930271212 cites W1997414854 @default.
• W1930271212 cites W2006874765 @default.
• W1930271212 cites W2013550305 @default.
• W1930271212 cites W2018342916 @default.
• W1930271212 cites W2018713713 @default.
• W1930271212 cites W2021575941 @default.
• W1930271212 cites W2021647455 @default.
• W1930271212 cites W2024101230 @default.
• W1930271212 cites W2028435485 @default.
• W1930271212 cites W2043951092 @default.
• W1930271212 cites W2048332220 @default.
• W1930271212 cites W2056280833 @default.
• W1930271212 cites W2058403714 @default.
• W1930271212 cites W2060736778 @default.
• W1930271212 cites W2062612767 @default.
• W1930271212 cites W2070168194 @default.
• W1930271212 cites W2074571786 @default.
• W1930271212 cites W2083219326 @default.
• W1930271212 cites W2092691551 @default.
• W1930271212 cites W2100880689 @default.
• W1930271212 cites W2109565344 @default.
• W1930271212 cites W2109843843 @default.
• W1930271212 cites W2116699098 @default.
• W1930271212 cites W2123613170 @default.
• W1930271212 cites W2125802398 @default.
• W1930271212 cites W2127286852 @default.
• W1930271212 cites W2138725608 @default.
• W1930271212 cites W2165628617 @default.
• W1930271212 cites W2167362667 @default.
• W1930271212 cites W2171080110 @default.
• W1930271212 cites W2227879028 @default.
• W1930271212 cites W2324152120 @default.
• W1930271212 cites W2402878994 @default.
• W1930271212 cites W2412035862 @default.
• W1930271212 cites W2412056179 @default.
• W1930271212 cites W2413621574 @default.
• W1930271212 cites W2416455757 @default.
• W1930271212 cites W2438241675 @default.
• W1930271212 cites W2604372607 @default.
• W1930271212 cites W57021689 @default.
• W1930271212 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11987443" @default.
• W1930271212 hasPublicationYear "2002" @default.
• W1930271212 type Work @default.
• W1930271212 sameAs 1930271212 @default.
• W1930271212 citedByCount "6" @default.
• W1930271212 crossrefType "journal-article" @default.
• W1930271212 hasAuthorship W1930271212A5010726382 @default.
• W1930271212 hasAuthorship W1930271212A5016496681 @default.
• W1930271212 hasAuthorship W1930271212A5061257711 @default.
• W1930271212 hasAuthorship W1930271212A5070997853 @default.
• W1930271212 hasConcept C121608353 @default.
• W1930271212 hasConcept C126322002 @default.
• W1930271212 hasConcept C177713679 @default.
• W1930271212 hasConcept C2780673598 @default.
• W1930271212 hasConcept C2780814781 @default.
• W1930271212 hasConcept C32220436 @default.
• W1930271212 hasConcept C512399662 @default.
• W1930271212 hasConcept C526805850 @default.
• W1930271212 hasConcept C60644358 @default.
• W1930271212 hasConcept C71924100 @default.
• W1930271212 hasConcept C86803240 @default.
• W1930271212 hasConceptScore W1930271212C121608353 @default.
• W1930271212 hasConceptScore W1930271212C126322002 @default.
• W1930271212 hasConceptScore W1930271212C177713679 @default.
• W1930271212 hasConceptScore W1930271212C2780673598 @default.
• W1930271212 hasConceptScore W1930271212C2780814781 @default.
• W1930271212 hasConceptScore W1930271212C32220436 @default.
• W1930271212 hasConceptScore W1930271212C512399662 @default.
• W1930271212 hasConceptScore W1930271212C526805850 @default.
• W1930271212 hasConceptScore W1930271212C60644358 @default.
• W1930271212 hasConceptScore W1930271212C71924100 @default.
• W1930271212 hasConceptScore W1930271212C86803240 @default.
• W1930271212 hasIssue "1" @default.
• W1930271212 hasLocation W19302712121 @default.
• W1930271212 hasOpenAccess W1930271212 @default.

• next