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- W193047871 abstract "Several hypolipidemic agents which are widely used in the prophylaxis of atherosclerosis in man have been shown recently to cause marked changes in the liver of rodents, including hepatomegaly, an increased number of peroxisomes, and induction1 of several peroxisomal enzymes which are predominantly involved in the metabolism of fatty acids (Cohen and Grasso 1981; Reddy and Lalwani 1983). Although negative as mutagens in the Ames test, these compounds have been demonstrated to be highly tumorigenic in mice and rats (Cohen and Grasso 1981)." @default.
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- W193047871 date "1988-01-01" @default.
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- W193047871 title "Concomitant Induction of Cytosolic Epoxide Hydrolase and Peroxisomal β-Oxidation by Hypolipidemic Compounds in Rat and Guinea Pig Liver" @default.
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- W193047871 doi "https://doi.org/10.1007/978-3-642-73113-6_40" @default.
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