FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1930483414> ?p ?o ?g. }

• W1930483414 endingPage "56a" @default.
• W1930483414 startingPage "56a" @default.
• W1930483414 abstract "Present recommendations for insulin injections in patients with diabetes are varied and at times controversial. One such recommendation is to inject insulin through the clothing provided the clothes and skin are reasonably clean.1 This practice allows the patient to administer the injection at an appropriate time in almost any place when outside home, with minimal disruption. There are some anecdotal reports2 of this being done successfully without any adverse reaction. However, any scientific evidence comes from a single short-term study1 where no major complication was noted over a period of 20 weeks. Neither the British3 nor the American4 diabetic authorities recommend this practice in their detailed instructions and advice for patients. Standard textbooks5 suggest that people with diabetes may be immunocompromised and prone to infection following minimal trauma.6 Abscesses resulting from insulin injection at injection sites are well-documented.6 Injecting through clothing may pose additional danger by carrying cloth fibres or contaminants from the clothes. A patient is currently being treated in our department whose history clearly demonstrates the risk. The patient is a 40-year-old woman who was diagnosed with type 1 diabetes when she was a teenager. Her physician at the time of diagnosis recommended injecting insulin through her clothing. Initially, she found this practice to be very convenient. She continued with this practice for about four years and discontinued only after the injection sites (her thighs) started to become painful and uncomfortable. She started to use other anatomical areas for the insulin injections directly through skin and had no significant problem for over 15 years. Her glycaemic control had been largely satisfactory over these years and she has not suffered from any other diabetes-related complications. For the last two years she had started to develop abscesses in both thighs which resulted in repeated episodes of poor glycaemic control requiring hospital admission. She also received repeated courses of various antibiotics during these two years. These abscesses presented over the anterior and lateral aspects of both thighs, in the areas where the patient used to administer her insulin injection through the clothing. She did not suffer from any infections or injection-related reactions in any of the current injection sites where she had been injecting directly through the skin. She has had 18 operations so far for drainage of abscesses and debridement and is likely to require more in the course of time (Figure 1). The operative findings have always been subcutaneous pus collection with varying amount of tissue necrosis. Though no foreign material visible to the naked eye has been found, foreign body reaction possibly related to her injection practice was suspected in the absence of any other explanation. Therefore, during the last two operations, debrided tissue was sent for histology and on both occasions this confirmed the presence of intense chronic active inflammatory process with foreign body giant-cell reaction. The patient's right thigh showing the scars from previous abscess drainage and further developing abscesses While one cannot be completely certain or prove that injecting insulin through clothing was responsible for this patient's problems, it seems to be highly likely under the circumstances. Our experience provides a note of caution against this practice. The author thanks Mr JM Porter, Consultant Plastic, Hand and Reconstructive Surgeon, Sandwell General Hospital, Birmingham, for kindly granting permission to report the findings of one of his patients." @default.
• W1930483414 created "2016-06-24" @default.
• W1930483414 creator A5010757419 @default.
• W1930483414 date "2006-01-01" @default.
• W1930483414 modified "2023-09-25" @default.
• W1930483414 title "Dangers of injecting insulin through clothing in diabetic people" @default.
• W1930483414 cites W2039894007 @default.
• W1930483414 cites W2158572140 @default.
• W1930483414 doi "https://doi.org/10.1002/pdi.896" @default.
• W1930483414 hasPublicationYear "2006" @default.
• W1930483414 type Work @default.
• W1930483414 sameAs 1930483414 @default.
• W1930483414 citedByCount "1" @default.
• W1930483414 countsByYear W19304834142023 @default.
• W1930483414 crossrefType "journal-article" @default.
• W1930483414 hasAuthorship W1930483414A5010757419 @default.
• W1930483414 hasBestOaLocation W19304834141 @default.
• W1930483414 hasConcept C126322002 @default.
• W1930483414 hasConcept C134018914 @default.
• W1930483414 hasConcept C141071460 @default.
• W1930483414 hasConcept C166957645 @default.
• W1930483414 hasConcept C177713679 @default.
• W1930483414 hasConcept C197934379 @default.
• W1930483414 hasConcept C206179267 @default.
• W1930483414 hasConcept C2777180221 @default.
• W1930483414 hasConcept C2779306644 @default.
• W1930483414 hasConcept C2779417425 @default.
• W1930483414 hasConcept C530175646 @default.
• W1930483414 hasConcept C555293320 @default.
• W1930483414 hasConcept C61434518 @default.
• W1930483414 hasConcept C71924100 @default.
• W1930483414 hasConcept C81182388 @default.
• W1930483414 hasConcept C95457728 @default.
• W1930483414 hasConceptScore W1930483414C126322002 @default.
• W1930483414 hasConceptScore W1930483414C134018914 @default.
• W1930483414 hasConceptScore W1930483414C141071460 @default.
• W1930483414 hasConceptScore W1930483414C166957645 @default.
• W1930483414 hasConceptScore W1930483414C177713679 @default.
• W1930483414 hasConceptScore W1930483414C197934379 @default.
• W1930483414 hasConceptScore W1930483414C206179267 @default.
• W1930483414 hasConceptScore W1930483414C2777180221 @default.
• W1930483414 hasConceptScore W1930483414C2779306644 @default.
• W1930483414 hasConceptScore W1930483414C2779417425 @default.
• W1930483414 hasConceptScore W1930483414C530175646 @default.
• W1930483414 hasConceptScore W1930483414C555293320 @default.
• W1930483414 hasConceptScore W1930483414C61434518 @default.
• W1930483414 hasConceptScore W1930483414C71924100 @default.
• W1930483414 hasConceptScore W1930483414C81182388 @default.
• W1930483414 hasConceptScore W1930483414C95457728 @default.
• W1930483414 hasIssue "2" @default.
• W1930483414 hasLocation W19304834141 @default.
• W1930483414 hasOpenAccess W1930483414 @default.
• W1930483414 hasPrimaryLocation W19304834141 @default.
• W1930483414 hasRelatedWork W1563850031 @default.
• W1930483414 hasRelatedWork W2003938723 @default.
• W1930483414 hasRelatedWork W2047967234 @default.
• W1930483414 hasRelatedWork W2069457352 @default.
• W1930483414 hasRelatedWork W2118496982 @default.
• W1930483414 hasRelatedWork W2369768841 @default.
• W1930483414 hasRelatedWork W2385621919 @default.
• W1930483414 hasRelatedWork W2439875401 @default.
• W1930483414 hasRelatedWork W4238867864 @default.
• W1930483414 hasRelatedWork W2525756941 @default.
• W1930483414 hasVolume "23" @default.
• W1930483414 isParatext "false" @default.
• W1930483414 isRetracted "false" @default.
• W1930483414 magId "1930483414" @default.
• W1930483414 workType "article" @default.