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• W1930961997 endingPage "e1045684" @default.
• W1930961997 startingPage "e1045684" @default.
• W1930961997 abstract "Cadherin-catenin mediated adhesion is an important determinant of tissue architecture in multicellular organisms. Cancer progression and maintenance is frequently associated with loss of their expression or functional activity, which not only leads to decreased cell-cell adhesion, but also to enhanced tumor cell proliferation and loss of differentiated characteristics. This review is focused on the emerging implications of cadherin-catenin proteins in the regulation of polarized divisions through their connections with the centrosomes, cytoskeleton, tissue tension and signaling pathways; and illustrates how alterations in cadherin-catenin levels or functional activity may render cells susceptible to transformation through the loss of their proliferation-differentiation balance." @default.
• W1930961997 created "2016-06-24" @default.
• W1930961997 creator A5004949644 @default.
• W1930961997 creator A5056199668 @default.
• W1930961997 date "2015-05-11" @default.
• W1930961997 modified "2023-10-17" @default.
• W1930961997 title "Connections between cadherin-catenin proteins, spindle misorientation, and cancer" @default.
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