FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1931431191> ?p ?o ?g. }

• W1931431191 endingPage "690" @default.
• W1931431191 startingPage "685" @default.
• W1931431191 abstract "Incidence of central nervous system (CNS) recurrence in patients with aggressive non-Hodgkin's lymphoma who did not receive meningeal prophylaxis is about 5%. Controversy remains regarding risk factors associated with such an event preventing a rational approach of prophylactic strategies.We analyzed a cohort of 974 patients with aggressive lymphoma in complete remission (CR). All the patients received a CNS prophylaxis consisting of intrathecal injections and intravenous high-dose methotrexate. The risk repartition on the basis of the international prognostic index (IPI) of these 974 CR-patients was low (L): 41%, low-intermediate (LI): 27%, high-intermediate (HI): 19%, high (H): 13%.The incidence of isolated CNS relapse was 1.6%. In a first multivariate logistic regression analysis an increased LDH (P = 0.05, RR = 5) and the presence of more than one extranodal site (P = 0.05, RR = 3) were identified as independent risk factors for isolated CNS relapse. Another multivariate analysis incorporating IPI as a unique parameter showed that only IPI remained significantly associated with a higher risk of CNS relapse (L-LI: 0.6% vs. HI H: 4.1%, P = 0.002; RR = 7).Prophylaxis notably reduces the risk of CNS recurrence in the higher risk patients. By contrast, we propose the deletion of prophylactic intrathecal injections in the lower risk patients." @default.
• W1931431191 created "2016-06-24" @default.
• W1931431191 creator A5003078312 @default.
• W1931431191 creator A5006559442 @default.
• W1931431191 creator A5018285104 @default.
• W1931431191 creator A5021483624 @default.
• W1931431191 creator A5025996929 @default.
• W1931431191 creator A5031041032 @default.
• W1931431191 creator A5033073385 @default.
• W1931431191 creator A5035242323 @default.
• W1931431191 creator A5044625155 @default.
• W1931431191 creator A5052452447 @default.
• W1931431191 creator A5055335263 @default.
• W1931431191 creator A5070084248 @default.
• W1931431191 date "2000-06-01" @default.
• W1931431191 modified "2023-10-16" @default.
• W1931431191 title "Incidence and risk factors of central nervous system relapse in histologically aggressive non-Hodgkin's lymphoma uniformly treated and receiving intrathecal central nervous system prophylaxis: A GELA study on 974 patients" @default.
• W1931431191 cites W1540690370 @default.
• W1931431191 cites W173609426 @default.
• W1931431191 cites W1885131295 @default.
• W1931431191 cites W1896652710 @default.
• W1931431191 cites W1946633639 @default.
• W1931431191 cites W1966387704 @default.
• W1931431191 cites W1990748358 @default.
• W1931431191 cites W2004156230 @default.
• W1931431191 cites W2067342652 @default.
• W1931431191 cites W2069455563 @default.
• W1931431191 cites W2082628262 @default.
• W1931431191 cites W2102068976 @default.
• W1931431191 cites W2156042731 @default.
• W1931431191 cites W2225927535 @default.
• W1931431191 cites W2338377114 @default.
• W1931431191 cites W2472782432 @default.
• W1931431191 cites W866601693 @default.
• W1931431191 doi "https://doi.org/10.1023/a:1008394827806" @default.
• W1931431191 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10942056" @default.
• W1931431191 hasPublicationYear "2000" @default.
• W1931431191 type Work @default.
• W1931431191 sameAs 1931431191 @default.
• W1931431191 citedByCount "192" @default.
• W1931431191 countsByYear W19314311912012 @default.
• W1931431191 countsByYear W19314311912013 @default.
• W1931431191 countsByYear W19314311912014 @default.
• W1931431191 countsByYear W19314311912015 @default.
• W1931431191 countsByYear W19314311912016 @default.
• W1931431191 countsByYear W19314311912017 @default.
• W1931431191 countsByYear W19314311912018 @default.
• W1931431191 countsByYear W19314311912019 @default.
• W1931431191 countsByYear W19314311912020 @default.
• W1931431191 countsByYear W19314311912021 @default.
• W1931431191 countsByYear W19314311912022 @default.
• W1931431191 countsByYear W19314311912023 @default.
• W1931431191 crossrefType "journal-article" @default.
• W1931431191 hasAuthorship W1931431191A5003078312 @default.
• W1931431191 hasAuthorship W1931431191A5006559442 @default.
• W1931431191 hasAuthorship W1931431191A5018285104 @default.
• W1931431191 hasAuthorship W1931431191A5021483624 @default.
• W1931431191 hasAuthorship W1931431191A5025996929 @default.
• W1931431191 hasAuthorship W1931431191A5031041032 @default.
• W1931431191 hasAuthorship W1931431191A5033073385 @default.
• W1931431191 hasAuthorship W1931431191A5035242323 @default.
• W1931431191 hasAuthorship W1931431191A5044625155 @default.
• W1931431191 hasAuthorship W1931431191A5052452447 @default.
• W1931431191 hasAuthorship W1931431191A5055335263 @default.
• W1931431191 hasAuthorship W1931431191A5070084248 @default.
• W1931431191 hasBestOaLocation W19314311911 @default.
• W1931431191 hasConcept C120665830 @default.
• W1931431191 hasConcept C121332964 @default.
• W1931431191 hasConcept C126322002 @default.
• W1931431191 hasConcept C141071460 @default.
• W1931431191 hasConcept C151956035 @default.
• W1931431191 hasConcept C2779338263 @default.
• W1931431191 hasConcept C2781059491 @default.
• W1931431191 hasConcept C44249647 @default.
• W1931431191 hasConcept C50440223 @default.
• W1931431191 hasConcept C529278444 @default.
• W1931431191 hasConcept C61511704 @default.
• W1931431191 hasConcept C71924100 @default.
• W1931431191 hasConcept C72563966 @default.
• W1931431191 hasConcept C82789193 @default.
• W1931431191 hasConcept C90924648 @default.
• W1931431191 hasConceptScore W1931431191C120665830 @default.
• W1931431191 hasConceptScore W1931431191C121332964 @default.
• W1931431191 hasConceptScore W1931431191C126322002 @default.
• W1931431191 hasConceptScore W1931431191C141071460 @default.
• W1931431191 hasConceptScore W1931431191C151956035 @default.
• W1931431191 hasConceptScore W1931431191C2779338263 @default.
• W1931431191 hasConceptScore W1931431191C2781059491 @default.
• W1931431191 hasConceptScore W1931431191C44249647 @default.
• W1931431191 hasConceptScore W1931431191C50440223 @default.
• W1931431191 hasConceptScore W1931431191C529278444 @default.
• W1931431191 hasConceptScore W1931431191C61511704 @default.
• W1931431191 hasConceptScore W1931431191C71924100 @default.
• W1931431191 hasConceptScore W1931431191C72563966 @default.
• W1931431191 hasConceptScore W1931431191C82789193 @default.
• W1931431191 hasConceptScore W1931431191C90924648 @default.
• W1931431191 hasIssue "6" @default.
• W1931431191 hasLocation W19314311911 @default.

• next