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• W1933423171 endingPage "98" @default.
• W1933423171 startingPage "88" @default.
• W1933423171 abstract "The vertebrate body axis extends sequentially from the posterior tip of the embryo, fueled by the gastrulation process at the primitive streak and its continuation within the tailbud. Anterior structures are generated early, and subsequent nascent tissues emerge from the posterior growth zone and continue to elongate the axis until its completion. The underlying processes have been shown to be disrupted in mouse mutants, some of which were described more than half a century ago.Important progress in elucidating the cellular and genetic events involved in body axis elongation has recently been made on several fronts. Evidence for the residence of self-renewing progenitors, some of which are bipotential for neurectoderm and mesoderm, has been obtained by embryo-grafting techniques and by clonal analyses in the mouse embryo. Transcription factors of several families including homeodomain proteins have proven instrumental for regulating the axial progenitor niche in the growth zone. A complex genetic network linking these transcription factors and signaling molecules is being unraveled that underlies the phenomenon of tissue lengthening from the axial stem cells. The concomitant events of cell fate decision among descendants of these progenitors begin to be better understood at the levels of molecular genetics and cell behavior.The emerging picture indicates that the ontogenesis of the successive body regions is regulated according to different rules. In addition, parameters controlling vertebrate axial length during evolution have emerged from comparative experimental studies. It is on these issues that this review will focus, mainly addressing the study of axial extension in the mouse embryo with some comparison with studies in chick and zebrafish, aiming at unveiling the recent progress, and pointing at still unanswered questions for a thorough understanding of the process of embryonic axis elongation." @default.
• W1933423171 created "2016-06-24" @default.
• W1933423171 creator A5006198242 @default.
• W1933423171 creator A5019724636 @default.
• W1933423171 creator A5036190530 @default.
• W1933423171 creator A5065428884 @default.
• W1933423171 creator A5079991612 @default.
• W1933423171 date "2013-09-06" @default.
• W1933423171 modified "2023-10-14" @default.
• W1933423171 title "Region-specific regulation of posterior axial elongation during vertebrate embryogenesis" @default.
• W1933423171 cites W1541821200 @default.
• W1933423171 cites W1768482373 @default.
• W1933423171 cites W1827288309 @default.
• W1933423171 cites W1829700783 @default.
• W1933423171 cites W1922337323 @default.
• W1933423171 cites W1932857191 @default.
• W1933423171 cites W1948282121 @default.
• W1933423171 cites W1962230110 @default.
• W1933423171 cites W1965634661 @default.
• W1933423171 cites W1971012578 @default.
• W1933423171 cites W1976435565 @default.
• W1933423171 cites W1977349921 @default.
• W1933423171 cites W1985023917 @default.
• W1933423171 cites W1985222746 @default.
• W1933423171 cites W1986007521 @default.
• W1933423171 cites W1987865998 @default.
• W1933423171 cites W1989965266 @default.
• W1933423171 cites W1990265275 @default.
• W1933423171 cites W1990818408 @default.
• W1933423171 cites W1993845489 @default.
• W1933423171 cites W1994769395 @default.
• W1933423171 cites W1996319176 @default.
• W1933423171 cites W2004543760 @default.
• W1933423171 cites W2005883936 @default.
• W1933423171 cites W2009096862 @default.
• W1933423171 cites W2013126973 @default.
• W1933423171 cites W2014514981 @default.
• W1933423171 cites W2020458486 @default.
• W1933423171 cites W2021759395 @default.
• W1933423171 cites W2022731947 @default.
• W1933423171 cites W2022853480 @default.
• W1933423171 cites W2029268112 @default.
• W1933423171 cites W2033401579 @default.
• W1933423171 cites W2039170732 @default.
• W1933423171 cites W2039233756 @default.
• W1933423171 cites W2043807089 @default.
• W1933423171 cites W2044779230 @default.
• W1933423171 cites W2044918998 @default.
• W1933423171 cites W2046213721 @default.
• W1933423171 cites W2047704995 @default.
• W1933423171 cites W2053626988 @default.
• W1933423171 cites W2054056658 @default.
• W1933423171 cites W2055397578 @default.
• W1933423171 cites W2056561438 @default.
• W1933423171 cites W2057749981 @default.
• W1933423171 cites W2058528119 @default.
• W1933423171 cites W2060045026 @default.
• W1933423171 cites W2064676044 @default.
• W1933423171 cites W2065528132 @default.
• W1933423171 cites W2069022895 @default.
• W1933423171 cites W2073969798 @default.
• W1933423171 cites W2075322700 @default.
• W1933423171 cites W2077843819 @default.
• W1933423171 cites W2078854027 @default.
• W1933423171 cites W2079244396 @default.
• W1933423171 cites W2079680354 @default.
• W1933423171 cites W2080549949 @default.
• W1933423171 cites W2081704147 @default.
• W1933423171 cites W2082843052 @default.
• W1933423171 cites W2083338784 @default.
• W1933423171 cites W2085382357 @default.
• W1933423171 cites W2085608448 @default.
• W1933423171 cites W2086345206 @default.
• W1933423171 cites W2087206546 @default.
• W1933423171 cites W2094208208 @default.
• W1933423171 cites W2095162330 @default.
• W1933423171 cites W2096448447 @default.
• W1933423171 cites W2099073211 @default.
• W1933423171 cites W2099143970 @default.
• W1933423171 cites W2100555636 @default.
• W1933423171 cites W2106803522 @default.
• W1933423171 cites W2109293927 @default.
• W1933423171 cites W2110825450 @default.
• W1933423171 cites W2112105989 @default.
• W1933423171 cites W2113320664 @default.
• W1933423171 cites W2115463333 @default.
• W1933423171 cites W2117265023 @default.
• W1933423171 cites W2122968962 @default.
• W1933423171 cites W2123604507 @default.
• W1933423171 cites W2123873776 @default.
• W1933423171 cites W2132368761 @default.
• W1933423171 cites W2135271831 @default.
• W1933423171 cites W2136570112 @default.
• W1933423171 cites W2145979705 @default.
• W1933423171 cites W2150013979 @default.
• W1933423171 cites W2156684099 @default.
• W1933423171 cites W2158470573 @default.
• W1933423171 cites W2161925383 @default.

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