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- W1933433452 abstract "Serious infections caused by Gram-positive pathogens are increasingly difficult to treat because of pathogens such as methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant enterococci (VRE) and penicillin-resistant Streptococcus pneumoniae. The more recent emergence of vancomycin-intermediate and -resistant MRSA (VISA and VRSA) has further compromised treatment options. Reports of resistance to, and clinical failures with newer antimicrobial agents such as linezolid and quinupristin/dalfopristin are also emerging. Consequently, there is a clinical need for new antimicrobial agents that have suitable pharmacokinetic properties and safety profiles, with activity against these Gram-positive pathogens." @default.
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- W1933433452 date "2005-01-01" @default.
- W1933433452 modified "2023-10-17" @default.
- W1933433452 title "Current and emerging serious Gram-positive infections" @default.
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- W1933433452 doi "https://doi.org/10.1111/j.1469-0691.2005.01138.x" @default.
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