FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1933572715> ?p ?o ?g. }

• W1933572715 abstract "Acute bronchiolitis is the most common cause for hospitalisation in infancy with 2–3% of all UK infants admitted in their first winter.1 ,2 It has a substantial health economic burden with annual costs in the USA of over $0.5 billion for hospital care alone.3 In addition to short-term morbidity, there are also associated long-term consequences with 40–50% of those admitted subsequently enduring recurrent wheeze.4 ,5 The significant impact of bronchiolitis has led to an extensive search for effective therapies over the last half century since Reynolds’ oft-quoted aphorism that “oxygen is vitally important in bronchiolitis and there is little convincing evidence that any other therapy is consistently, or even occasionally, useful”.6Nebulised hypertonic saline represents an attractive potential treatment for bronchiolitis. Hypertonic saline improves both mucous rheology (elasticity and viscosity) and mucociliary clearance in vitro7 ,8 with clinical studies in cystic fibrosis demonstrating beneficial effects on pulmonary exacerbation rates.9 Bronchiolitis has a number of pathophysiological features, including increased mucous production, airway oedema and mucous plugging, which could potentially be amenable to treatment with hypertonic saline.10Since the first published trial of hypertonic saline from Israel in 2002,11 there have been almost 20 randomised controlled studies published of its use in bronchiolitis. Unfortunately, overall interpretation of these studies is hampered by factors that have repeatedly beleaguered bronchiolitis research. One of the principal difficulties is the lack of an internationally recognised bronchiolitis definition. In the UK, Australasia and some parts of Europe, the diagnosis is based on the presence of cough, tachypnoea and widespread inspiratory crackles.12 In North America and many other parts of the world, bronchiolitis is diagnosed when a young child has a first episode of wheeze with increased work of breathing in the presence of an …" @default.
• W1933572715 created "2016-06-24" @default.
• W1933572715 creator A5057275763 @default.
• W1933572715 creator A5087008695 @default.
• W1933572715 date "2015-07-27" @default.
• W1933572715 modified "2023-09-23" @default.
• W1933572715 title "Hypertonic saline for bronchiolitis: a case of less is more" @default.
• W1933572715 cites W1556300958 @default.
• W1933572715 cites W1874558591 @default.
• W1933572715 cites W1968152866 @default.
• W1933572715 cites W1976865805 @default.
• W1933572715 cites W1994310413 @default.
• W1933572715 cites W2004642804 @default.
• W1933572715 cites W2012903885 @default.
• W1933572715 cites W2025966574 @default.
• W1933572715 cites W2028066606 @default.
• W1933572715 cites W2049987360 @default.
• W1933572715 cites W2067640690 @default.
• W1933572715 cites W2075007772 @default.
• W1933572715 cites W2098568613 @default.
• W1933572715 cites W2103043501 @default.
• W1933572715 cites W2103840342 @default.
• W1933572715 cites W2108403027 @default.
• W1933572715 cites W2114974145 @default.
• W1933572715 cites W2127825607 @default.
• W1933572715 cites W2127937823 @default.
• W1933572715 cites W2139649226 @default.
• W1933572715 cites W2143348774 @default.
• W1933572715 cites W2156132844 @default.
• W1933572715 cites W2156304672 @default.
• W1933572715 cites W2159584260 @default.
• W1933572715 cites W2161034088 @default.
• W1933572715 cites W2162742958 @default.
• W1933572715 cites W2183598380 @default.
• W1933572715 cites W2289913499 @default.
• W1933572715 cites W2322654587 @default.
• W1933572715 cites W41545582 @default.
• W1933572715 doi "https://doi.org/10.1136/archdischild-2014-308039" @default.
• W1933572715 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26216830" @default.
• W1933572715 hasPublicationYear "2015" @default.
• W1933572715 type Work @default.
• W1933572715 sameAs 1933572715 @default.
• W1933572715 citedByCount "2" @default.
• W1933572715 countsByYear W19335727152015 @default.
• W1933572715 countsByYear W19335727152021 @default.
• W1933572715 crossrefType "journal-article" @default.
• W1933572715 hasAuthorship W1933572715A5057275763 @default.
• W1933572715 hasAuthorship W1933572715A5087008695 @default.
• W1933572715 hasConcept C114682108 @default.
• W1933572715 hasConcept C126322002 @default.
• W1933572715 hasConcept C177713679 @default.
• W1933572715 hasConcept C187212893 @default.
• W1933572715 hasConcept C2776042228 @default.
• W1933572715 hasConcept C2777714996 @default.
• W1933572715 hasConcept C2778821649 @default.
• W1933572715 hasConcept C3017567848 @default.
• W1933572715 hasConcept C42219234 @default.
• W1933572715 hasConcept C534529494 @default.
• W1933572715 hasConcept C71924100 @default.
• W1933572715 hasConceptScore W1933572715C114682108 @default.
• W1933572715 hasConceptScore W1933572715C126322002 @default.
• W1933572715 hasConceptScore W1933572715C177713679 @default.
• W1933572715 hasConceptScore W1933572715C187212893 @default.
• W1933572715 hasConceptScore W1933572715C2776042228 @default.
• W1933572715 hasConceptScore W1933572715C2777714996 @default.
• W1933572715 hasConceptScore W1933572715C2778821649 @default.
• W1933572715 hasConceptScore W1933572715C3017567848 @default.
• W1933572715 hasConceptScore W1933572715C42219234 @default.
• W1933572715 hasConceptScore W1933572715C534529494 @default.
• W1933572715 hasConceptScore W1933572715C71924100 @default.
• W1933572715 hasLocation W19335727151 @default.
• W1933572715 hasLocation W19335727152 @default.
• W1933572715 hasOpenAccess W1933572715 @default.
• W1933572715 hasPrimaryLocation W19335727151 @default.
• W1933572715 hasRelatedWork W163908647 @default.
• W1933572715 hasRelatedWork W16429565 @default.
• W1933572715 hasRelatedWork W1861030242 @default.
• W1933572715 hasRelatedWork W1964639859 @default.
• W1933572715 hasRelatedWork W2002033674 @default.
• W1933572715 hasRelatedWork W21261013 @default.
• W1933572715 hasRelatedWork W2126350035 @default.
• W1933572715 hasRelatedWork W2140956052 @default.
• W1933572715 hasRelatedWork W2142076005 @default.
• W1933572715 hasRelatedWork W2151358248 @default.
• W1933572715 hasRelatedWork W2152460496 @default.
• W1933572715 hasRelatedWork W2314043182 @default.
• W1933572715 hasRelatedWork W2432004870 @default.
• W1933572715 hasRelatedWork W2474259425 @default.
• W1933572715 hasRelatedWork W2794560593 @default.
• W1933572715 hasRelatedWork W2884612940 @default.
• W1933572715 hasRelatedWork W2992365705 @default.
• W1933572715 hasRelatedWork W3025003101 @default.
• W1933572715 hasRelatedWork W41472740 @default.
• W1933572715 hasRelatedWork W3027726029 @default.
• W1933572715 isParatext "false" @default.
• W1933572715 isRetracted "false" @default.
• W1933572715 magId "1933572715" @default.
• W1933572715 workType "article" @default.