FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1934064182> ?p ?o ?g. }

• W1934064182 endingPage "C185" @default.
• W1934064182 startingPage "C175" @default.
• W1934064182 abstract "Stimulation-induced changes in Cl- content and O2 consumption of collagenase-isolated rat parotid acini were measured. In less than 10 s, carbachol caused a net Cl- efflux, corresponding to approximately 50% of the Cl- content, and increased the O2 uptake by 100%. The increase was inhibitable by ouabain and was dependent on the presence of extracellular Ca2+. Furosemide reduced the unstimulated 36Cl- uptake and prevented the reuptake of Cl- after carbachol-induced release. This suggests that a cotransport system is operating in both the unstimulated and stimulated states. Furthermore, furosemide inhibited the stimulated ouabain-sensitive O2 uptake. Raising intracellular Ca2+ by the calcium ionophore A23187 evoked the same pattern of Cl- loss and O2 uptake as carbachol. Our results are compatible with the following hypothesis. Carbachol raises intracellular Ca2+, causing an increased Cl- permeability of the luminal membrane, resulting in a net Cl- efflux. A subsequently enhanced influx of Cl- and Na+ via a furosemide-sensitive cotransport system increases intracellular Na+. This stimulates the Na+-K+-ATPase and thereby the O2 consumption." @default.
• W1934064182 created "2016-06-24" @default.
• W1934064182 creator A5049792146 @default.
• W1934064182 creator A5087335318 @default.
• W1934064182 date "1986-08-01" @default.
• W1934064182 modified "2023-10-17" @default.
• W1934064182 title "Effects of Ca2+ and furosemide on Cl- transport and O2 uptake in rat parotid acini" @default.
• W1934064182 cites W1517410809 @default.
• W1934064182 cites W1964430102 @default.
• W1934064182 cites W1965645852 @default.
• W1934064182 cites W1967077088 @default.
• W1934064182 cites W1982555176 @default.
• W1934064182 cites W1996455275 @default.
• W1934064182 cites W2003238081 @default.
• W1934064182 cites W2005809724 @default.
• W1934064182 cites W2020330169 @default.
• W1934064182 cites W2033817793 @default.
• W1934064182 cites W2039638368 @default.
• W1934064182 cites W2043125356 @default.
• W1934064182 cites W2055108276 @default.
• W1934064182 cites W2057530697 @default.
• W1934064182 cites W2061827989 @default.
• W1934064182 cites W2062568439 @default.
• W1934064182 cites W2064946020 @default.
• W1934064182 cites W2104670373 @default.
• W1934064182 cites W2337373837 @default.
• W1934064182 doi "https://doi.org/10.1152/ajpcell.1986.251.2.c175" @default.
• W1934064182 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2426956" @default.
• W1934064182 hasPublicationYear "1986" @default.
• W1934064182 type Work @default.
• W1934064182 sameAs 1934064182 @default.
• W1934064182 citedByCount "87" @default.
• W1934064182 countsByYear W19340641822012 @default.
• W1934064182 countsByYear W19340641822014 @default.
• W1934064182 countsByYear W19340641822015 @default.
• W1934064182 countsByYear W19340641822016 @default.
• W1934064182 countsByYear W19340641822017 @default.
• W1934064182 countsByYear W19340641822020 @default.
• W1934064182 countsByYear W19340641822022 @default.
• W1934064182 crossrefType "journal-article" @default.
• W1934064182 hasAuthorship W1934064182A5049792146 @default.
• W1934064182 hasAuthorship W1934064182A5087335318 @default.
• W1934064182 hasConcept C12554922 @default.
• W1934064182 hasConcept C126322002 @default.
• W1934064182 hasConcept C134018914 @default.
• W1934064182 hasConcept C178790620 @default.
• W1934064182 hasConcept C185592680 @default.
• W1934064182 hasConcept C188053792 @default.
• W1934064182 hasConcept C200082930 @default.
• W1934064182 hasConcept C24998067 @default.
• W1934064182 hasConcept C2776989580 @default.
• W1934064182 hasConcept C2777955127 @default.
• W1934064182 hasConcept C2778212192 @default.
• W1934064182 hasConcept C2778988552 @default.
• W1934064182 hasConcept C2779133857 @default.
• W1934064182 hasConcept C2779608910 @default.
• W1934064182 hasConcept C28406088 @default.
• W1934064182 hasConcept C41625074 @default.
• W1934064182 hasConcept C519063684 @default.
• W1934064182 hasConcept C537181965 @default.
• W1934064182 hasConcept C55493867 @default.
• W1934064182 hasConcept C71924100 @default.
• W1934064182 hasConcept C79879829 @default.
• W1934064182 hasConcept C86803240 @default.
• W1934064182 hasConcept C99975950 @default.
• W1934064182 hasConceptScore W1934064182C12554922 @default.
• W1934064182 hasConceptScore W1934064182C126322002 @default.
• W1934064182 hasConceptScore W1934064182C134018914 @default.
• W1934064182 hasConceptScore W1934064182C178790620 @default.
• W1934064182 hasConceptScore W1934064182C185592680 @default.
• W1934064182 hasConceptScore W1934064182C188053792 @default.
• W1934064182 hasConceptScore W1934064182C200082930 @default.
• W1934064182 hasConceptScore W1934064182C24998067 @default.
• W1934064182 hasConceptScore W1934064182C2776989580 @default.
• W1934064182 hasConceptScore W1934064182C2777955127 @default.
• W1934064182 hasConceptScore W1934064182C2778212192 @default.
• W1934064182 hasConceptScore W1934064182C2778988552 @default.
• W1934064182 hasConceptScore W1934064182C2779133857 @default.
• W1934064182 hasConceptScore W1934064182C2779608910 @default.
• W1934064182 hasConceptScore W1934064182C28406088 @default.
• W1934064182 hasConceptScore W1934064182C41625074 @default.
• W1934064182 hasConceptScore W1934064182C519063684 @default.
• W1934064182 hasConceptScore W1934064182C537181965 @default.
• W1934064182 hasConceptScore W1934064182C55493867 @default.
• W1934064182 hasConceptScore W1934064182C71924100 @default.
• W1934064182 hasConceptScore W1934064182C79879829 @default.
• W1934064182 hasConceptScore W1934064182C86803240 @default.
• W1934064182 hasConceptScore W1934064182C99975950 @default.
• W1934064182 hasIssue "2" @default.
• W1934064182 hasLocation W19340641821 @default.
• W1934064182 hasLocation W19340641822 @default.
• W1934064182 hasOpenAccess W1934064182 @default.
• W1934064182 hasPrimaryLocation W19340641821 @default.
• W1934064182 hasRelatedWork W1510209247 @default.
• W1934064182 hasRelatedWork W1934064182 @default.
• W1934064182 hasRelatedWork W1961939200 @default.
• W1934064182 hasRelatedWork W1970874995 @default.
• W1934064182 hasRelatedWork W1988331277 @default.

• next