Matches in SemOpenAlex for { <https://semopenalex.org/work/W1934334043> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W1934334043 endingPage "5" @default.
- W1934334043 startingPage "281" @default.
- W1934334043 abstract "We compared bronchial responsiveness to isocapnic hyperventilation of cold dry air at -18 degrees C and 0% humidity with bronchial responsiveness to inhaled methacholine in 24 subjects with current or previous asthma and 2 nonasthmatics. Two inhalation tests with each agent were carried out in random order on 4 consecutive days. The response to cold air was expressed as the respiratory heat exchange required to reduce the FEV1 by 10% (PD10 RHE) and the response to methacholine as the provocation concentration required to reduce the FEV1 by 20% (PC20 methacholine). There was a close positive linear correlation between PD10 RHE and PC20 (r = 0.86, p less than 0.001). The responsiveness to each agent was highly reproducible. The PD10 RHE could be measured in all 21 subjects with current symptoms of asthma and it could be obtained by extrapolation in 2 normal subjects, but it could not be measured in 3 subjects with a past history of asthma. The PC20 in the current asthmatics was 6.3 mg/ml or less, in the 2 nonasthmatic subjects, it was 14 and 16 mg/ml, and in the previous asthmatics it was between 26 and 54 mg/ml. The results indicate that nonspecific bronchial responsiveness is an important factor influencing the bronchial response to cold air, that either cold air or methacholine are suitable stimuli to measure nonspecific bronchial responsiveness, and that the differences in bronchial responsiveness observed between asthmatics and nonasthmatic subjects are in keeping with a quantitative rather than a qualitative difference in responsiveness." @default.
- W1934334043 created "2016-06-24" @default.
- W1934334043 creator A5009675319 @default.
- W1934334043 creator A5012177176 @default.
- W1934334043 creator A5020140008 @default.
- W1934334043 creator A5026242254 @default.
- W1934334043 creator A5027185413 @default.
- W1934334043 creator A5031673880 @default.
- W1934334043 creator A5042721578 @default.
- W1934334043 date "1982-03-01" @default.
- W1934334043 modified "2023-09-26" @default.
- W1934334043 title "Asthma induced by cold air and its relation to nonspecific bronchial responsiveness to methacholine." @default.
- W1934334043 cites W1937027352 @default.
- W1934334043 cites W1945429092 @default.
- W1934334043 cites W1984957837 @default.
- W1934334043 cites W1991358606 @default.
- W1934334043 cites W1994939174 @default.
- W1934334043 cites W1995553664 @default.
- W1934334043 cites W2039044160 @default.
- W1934334043 cites W2075028746 @default.
- W1934334043 cites W2097665064 @default.
- W1934334043 cites W2134268711 @default.
- W1934334043 cites W2315751981 @default.
- W1934334043 cites W2419614813 @default.
- W1934334043 cites W2444287088 @default.
- W1934334043 doi "https://doi.org/10.1164/arrd.1982.125.3.281" @default.
- W1934334043 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7039437" @default.
- W1934334043 hasPublicationYear "1982" @default.
- W1934334043 type Work @default.
- W1934334043 sameAs 1934334043 @default.
- W1934334043 citedByCount "101" @default.
- W1934334043 countsByYear W19343340432013 @default.
- W1934334043 countsByYear W19343340432016 @default.
- W1934334043 countsByYear W19343340432017 @default.
- W1934334043 countsByYear W19343340432018 @default.
- W1934334043 countsByYear W19343340432021 @default.
- W1934334043 crossrefType "journal-article" @default.
- W1934334043 hasAuthorship W1934334043A5009675319 @default.
- W1934334043 hasAuthorship W1934334043A5012177176 @default.
- W1934334043 hasAuthorship W1934334043A5020140008 @default.
- W1934334043 hasAuthorship W1934334043A5026242254 @default.
- W1934334043 hasAuthorship W1934334043A5027185413 @default.
- W1934334043 hasAuthorship W1934334043A5031673880 @default.
- W1934334043 hasAuthorship W1934334043A5042721578 @default.
- W1934334043 hasConcept C110586980 @default.
- W1934334043 hasConcept C126322002 @default.
- W1934334043 hasConcept C142724271 @default.
- W1934334043 hasConcept C204787440 @default.
- W1934334043 hasConcept C2776042228 @default.
- W1934334043 hasConcept C2776178081 @default.
- W1934334043 hasConcept C2776238763 @default.
- W1934334043 hasConcept C2776954882 @default.
- W1934334043 hasConcept C2777449187 @default.
- W1934334043 hasConcept C2777714996 @default.
- W1934334043 hasConcept C2781260171 @default.
- W1934334043 hasConcept C42219234 @default.
- W1934334043 hasConcept C534529494 @default.
- W1934334043 hasConcept C71924100 @default.
- W1934334043 hasConceptScore W1934334043C110586980 @default.
- W1934334043 hasConceptScore W1934334043C126322002 @default.
- W1934334043 hasConceptScore W1934334043C142724271 @default.
- W1934334043 hasConceptScore W1934334043C204787440 @default.
- W1934334043 hasConceptScore W1934334043C2776042228 @default.
- W1934334043 hasConceptScore W1934334043C2776178081 @default.
- W1934334043 hasConceptScore W1934334043C2776238763 @default.
- W1934334043 hasConceptScore W1934334043C2776954882 @default.
- W1934334043 hasConceptScore W1934334043C2777449187 @default.
- W1934334043 hasConceptScore W1934334043C2777714996 @default.
- W1934334043 hasConceptScore W1934334043C2781260171 @default.
- W1934334043 hasConceptScore W1934334043C42219234 @default.
- W1934334043 hasConceptScore W1934334043C534529494 @default.
- W1934334043 hasConceptScore W1934334043C71924100 @default.
- W1934334043 hasIssue "3" @default.
- W1934334043 hasLocation W19343340431 @default.
- W1934334043 hasOpenAccess W1934334043 @default.
- W1934334043 hasPrimaryLocation W19343340431 @default.
- W1934334043 hasRelatedWork W1919304416 @default.
- W1934334043 hasRelatedWork W1934334043 @default.
- W1934334043 hasRelatedWork W2053704541 @default.
- W1934334043 hasRelatedWork W2121791204 @default.
- W1934334043 hasRelatedWork W2129552571 @default.
- W1934334043 hasRelatedWork W2319742400 @default.
- W1934334043 hasRelatedWork W2406196384 @default.
- W1934334043 hasRelatedWork W2430617564 @default.
- W1934334043 hasRelatedWork W2431791950 @default.
- W1934334043 hasRelatedWork W2785480900 @default.
- W1934334043 hasVolume "125" @default.
- W1934334043 isParatext "false" @default.
- W1934334043 isRetracted "false" @default.
- W1934334043 magId "1934334043" @default.
- W1934334043 workType "article" @default.