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• W1934364412 abstract "Different noncellular elements, such as round concentric calcified laminated structures, may be found in sputum smears. If these structures appear isolated on the background of the smear, the term usually used to describe them is calcareous concretions (CC). On the contrary, when the structures are part of epithelial cell groups or small tissue fragments, the term used to describe them is Psammoma bodies (PB). The aim of this work is to establish the relationship between these structures and pulmonary disease, especially lung carcinoma, by searching for the presence of CC and/or PB in sputum smears. Our study has taken as a basis 16.716 sputum smears from 696 patients obtained during a 7-year period (2003-2009). After reviewing them, it was found that from the total, 66 cases (0.39%) contained round calcified structures, 57 of them (0.34%) corresponding to CC, and the remaining 9 ones (0.05%) corresponding to PB. From these 57 CC cases, 56 corresponded to benign entities, and only one was found with lung carcinoma. On the other hand, from the 9 PB cases all of them (100%) were related to lung adenocarcinoma. We conclude that, even having a similar morphological structure, these aforementioned calcified structures we have observed in sputum smears have different and relevant clinical significance." @default.
• W1934364412 created "2016-06-24" @default.
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• W1934364412 date "2014-02-18" @default.
• W1934364412 modified "2023-10-06" @default.
• W1934364412 title "Calcareous concretions and psammoma bodies in sputum smears: Do these similar structures have different clinical significance?" @default.
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• W1934364412 doi "https://doi.org/10.1002/dc.23120" @default.
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