Matches in SemOpenAlex for { <https://semopenalex.org/work/W1934412657> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W1934412657 abstract "The Prostate Cancer Foundation-Movember Foundation Reproducibility Initiative seeks to address growing concerns about reproducibility in scientific research by conducting replications of recent papers in the field of prostate cancer. This Registered Report describes the proposed replication plan of key experiments from Androgen Receptor Splice Variants Determine Taxane Sensitivity in Prostate Cancer by Thadani-Mulero and colleagues (2014) published in Cancer Research in 2014. The experiment that will be replicated is reported in Fig. 6A. Thadani-Mulero and colleagues generated xenografts from two prostate cancer cell lines; LuCaP 86.2, which expresses predominantly the ARv567 splice variant of the androgen receptor (AR), and LuCaP 23.1, which expresses the full length AR as well as the ARv7 variant. Treatment of the tumors with the taxane docetaxel showed that the drug inhibited tumor growth of the LuCaP 86.2 cells but not of the LuCaP 23.1 cells, indicating that expression of splice variants of the AR can affect sensitivity to docetaxel. The Prostate Cancer Foundation-Movember Foundation Reproducibility Initiative is a collaboration between the Prostate Cancer Foundation, the Movember Foundation and Science Exchange, and the results of the replications will be published by PeerJ." @default.
- W1934412657 created "2016-06-24" @default.
- W1934412657 creator A5009629991 @default.
- W1934412657 creator A5025501442 @default.
- W1934412657 creator A5032399712 @default.
- W1934412657 creator A5040386046 @default.
- W1934412657 creator A5049870122 @default.
- W1934412657 creator A5065906497 @default.
- W1934412657 creator A5075979759 @default.
- W1934412657 creator A5082073517 @default.
- W1934412657 date "2015-09-15" @default.
- W1934412657 modified "2023-09-25" @default.
- W1934412657 title "Registered report: androgen receptor splice variants determine taxane sensitivity in prostate cancer" @default.
- W1934412657 cites W1917534569 @default.
- W1934412657 cites W1992624438 @default.
- W1934412657 cites W2005302422 @default.
- W1934412657 cites W2028539169 @default.
- W1934412657 cites W2069541720 @default.
- W1934412657 cites W2071753433 @default.
- W1934412657 cites W2087484885 @default.
- W1934412657 cites W2118018514 @default.
- W1934412657 cites W2123629153 @default.
- W1934412657 cites W2137340845 @default.
- W1934412657 cites W2157980218 @default.
- W1934412657 cites W2171309933 @default.
- W1934412657 cites W2414997971 @default.
- W1934412657 doi "https://doi.org/10.7717/peerj.1232" @default.
- W1934412657 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4579034" @default.
- W1934412657 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26401448" @default.
- W1934412657 hasPublicationYear "2015" @default.
- W1934412657 type Work @default.
- W1934412657 sameAs 1934412657 @default.
- W1934412657 citedByCount "6" @default.
- W1934412657 countsByYear W19344126572017 @default.
- W1934412657 countsByYear W19344126572018 @default.
- W1934412657 countsByYear W19344126572019 @default.
- W1934412657 crossrefType "journal-article" @default.
- W1934412657 hasAuthorship W1934412657A5009629991 @default.
- W1934412657 hasAuthorship W1934412657A5025501442 @default.
- W1934412657 hasAuthorship W1934412657A5032399712 @default.
- W1934412657 hasAuthorship W1934412657A5040386046 @default.
- W1934412657 hasAuthorship W1934412657A5049870122 @default.
- W1934412657 hasAuthorship W1934412657A5065906497 @default.
- W1934412657 hasAuthorship W1934412657A5075979759 @default.
- W1934412657 hasAuthorship W1934412657A5082073517 @default.
- W1934412657 hasBestOaLocation W19344126571 @default.
- W1934412657 hasConcept C121608353 @default.
- W1934412657 hasConcept C126322002 @default.
- W1934412657 hasConcept C143998085 @default.
- W1934412657 hasConcept C2776235491 @default.
- W1934412657 hasConcept C2777511904 @default.
- W1934412657 hasConcept C2780192828 @default.
- W1934412657 hasConcept C2781190966 @default.
- W1934412657 hasConcept C502942594 @default.
- W1934412657 hasConcept C530470458 @default.
- W1934412657 hasConcept C61367390 @default.
- W1934412657 hasConcept C71924100 @default.
- W1934412657 hasConceptScore W1934412657C121608353 @default.
- W1934412657 hasConceptScore W1934412657C126322002 @default.
- W1934412657 hasConceptScore W1934412657C143998085 @default.
- W1934412657 hasConceptScore W1934412657C2776235491 @default.
- W1934412657 hasConceptScore W1934412657C2777511904 @default.
- W1934412657 hasConceptScore W1934412657C2780192828 @default.
- W1934412657 hasConceptScore W1934412657C2781190966 @default.
- W1934412657 hasConceptScore W1934412657C502942594 @default.
- W1934412657 hasConceptScore W1934412657C530470458 @default.
- W1934412657 hasConceptScore W1934412657C61367390 @default.
- W1934412657 hasConceptScore W1934412657C71924100 @default.
- W1934412657 hasLocation W19344126571 @default.
- W1934412657 hasLocation W19344126572 @default.
- W1934412657 hasLocation W19344126573 @default.
- W1934412657 hasLocation W19344126574 @default.
- W1934412657 hasLocation W19344126575 @default.
- W1934412657 hasOpenAccess W1934412657 @default.
- W1934412657 hasPrimaryLocation W19344126571 @default.
- W1934412657 hasRelatedWork W1802073358 @default.
- W1934412657 hasRelatedWork W2014434161 @default.
- W1934412657 hasRelatedWork W2094570582 @default.
- W1934412657 hasRelatedWork W2161225819 @default.
- W1934412657 hasRelatedWork W2735900144 @default.
- W1934412657 hasRelatedWork W2776356588 @default.
- W1934412657 hasRelatedWork W287696284 @default.
- W1934412657 hasRelatedWork W2901274396 @default.
- W1934412657 hasRelatedWork W3023947295 @default.
- W1934412657 hasRelatedWork W3138747339 @default.
- W1934412657 isParatext "false" @default.
- W1934412657 isRetracted "false" @default.
- W1934412657 magId "1934412657" @default.
- W1934412657 workType "article" @default.