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- W1934624334 abstract "Summary Background Butyrate, a short‐chain fatty acid, is a main end‐product of intestinal microbial fermentation of mainly dietary fibre. Butyrate is an important energy source for intestinal epithelial cells and plays a role in the maintenance of colonic homeostasis. Aim To provide an overview on the present knowledge of the bioactivity of butyrate, emphasizing effects and possible mechanisms of action in relation to human colonic function. Methods A PubMed search was performed to select relevant publications using the search terms: ‘butyrate, short‐chain fatty acid, fibre, colon, inflammation, carcinogenesis, barrier, oxidative stress, permeability and satiety’. Results Butyrate exerts potent effects on a variety of colonic mucosal functions such as inhibition of inflammation and carcinogenesis, reinforcing various components of the colonic defence barrier and decreasing oxidative stress. In addition, butyrate may promote satiety. Two important mechanisms include the inhibition of nuclear factor kappa B activation and histone deacetylation. However, the observed effects of butyrate largely depend on concentrations and models used and human data are still limited. Conclusion Although most studies point towards beneficial effects of butyrate, more human in vivo studies are needed to contribute to our current understanding of butyrate‐mediated effects on colonic function in health and disease." @default.
- W1934624334 created "2016-06-24" @default.
- W1934624334 creator A5001484811 @default.
- W1934624334 creator A5034594973 @default.
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- W1934624334 creator A5048065759 @default.
- W1934624334 creator A5058784327 @default.
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- W1934624334 date "2007-10-26" @default.
- W1934624334 modified "2023-10-18" @default.
- W1934624334 title "Review article: the role of butyrate on colonic function" @default.
- W1934624334 cites W1579473562 @default.
- W1934624334 cites W1588926099 @default.
- W1934624334 cites W161474139 @default.
- W1934624334 cites W1779033144 @default.
- W1934624334 cites W1800141310 @default.
- W1934624334 cites W1877854700 @default.
- W1934624334 cites W1905504015 @default.
- W1934624334 cites W1922189421 @default.
- W1934624334 cites W1945596138 @default.
- W1934624334 cites W1946872333 @default.
- W1934624334 cites W1953702613 @default.
- W1934624334 cites W1963485882 @default.
- W1934624334 cites W1963789180 @default.
- W1934624334 cites W1967287514 @default.
- W1934624334 cites W1967917438 @default.
- W1934624334 cites W1967989259 @default.
- W1934624334 cites W1969507911 @default.
- W1934624334 cites W1970764069 @default.
- W1934624334 cites W1971016902 @default.
- W1934624334 cites W1971948897 @default.
- W1934624334 cites W1974707545 @default.
- W1934624334 cites W1975165265 @default.
- W1934624334 cites W1977087431 @default.
- W1934624334 cites W1977307485 @default.
- W1934624334 cites W1978039719 @default.
- W1934624334 cites W1978510451 @default.
- W1934624334 cites W1978627004 @default.
- W1934624334 cites W1979484507 @default.
- W1934624334 cites W1981415431 @default.
- W1934624334 cites W1988435059 @default.
- W1934624334 cites W1990462552 @default.
- W1934624334 cites W1990884844 @default.
- W1934624334 cites W1991926127 @default.
- W1934624334 cites W1994767796 @default.
- W1934624334 cites W1996071034 @default.
- W1934624334 cites W1997822058 @default.
- W1934624334 cites W1998314317 @default.
- W1934624334 cites W2001777781 @default.
- W1934624334 cites W2002600239 @default.
- W1934624334 cites W2003504227 @default.
- W1934624334 cites W2004506978 @default.
- W1934624334 cites W2005301170 @default.
- W1934624334 cites W2005449040 @default.
- W1934624334 cites W2006997039 @default.
- W1934624334 cites W2007278577 @default.
- W1934624334 cites W2008793548 @default.
- W1934624334 cites W2008981449 @default.
- W1934624334 cites W2009108161 @default.
- W1934624334 cites W2009383010 @default.
- W1934624334 cites W2009781762 @default.
- W1934624334 cites W2010139988 @default.
- W1934624334 cites W2010184221 @default.
- W1934624334 cites W2010713573 @default.
- W1934624334 cites W2012397835 @default.
- W1934624334 cites W2012604741 @default.
- W1934624334 cites W2013088311 @default.
- W1934624334 cites W2014174473 @default.
- W1934624334 cites W2017235895 @default.
- W1934624334 cites W2017761896 @default.
- W1934624334 cites W2017917348 @default.
- W1934624334 cites W2019521764 @default.
- W1934624334 cites W2019819611 @default.
- W1934624334 cites W2019833815 @default.
- W1934624334 cites W2019841932 @default.
- W1934624334 cites W2022075338 @default.
- W1934624334 cites W2022118330 @default.
- W1934624334 cites W2027551123 @default.
- W1934624334 cites W2030350827 @default.
- W1934624334 cites W2032012050 @default.
- W1934624334 cites W2033057608 @default.
- W1934624334 cites W2033494912 @default.
- W1934624334 cites W2033540301 @default.
- W1934624334 cites W2034217591 @default.
- W1934624334 cites W2035397525 @default.
- W1934624334 cites W2035421462 @default.
- W1934624334 cites W2036547532 @default.
- W1934624334 cites W2037111559 @default.
- W1934624334 cites W2040197132 @default.
- W1934624334 cites W2041059386 @default.
- W1934624334 cites W2041972891 @default.
- W1934624334 cites W2043251061 @default.
- W1934624334 cites W2044511863 @default.
- W1934624334 cites W2045348654 @default.
- W1934624334 cites W2048125796 @default.
- W1934624334 cites W2048551062 @default.
- W1934624334 cites W2051605214 @default.
- W1934624334 cites W2051846981 @default.