FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1934701412> ?p ?o ?g. }

• W1934701412 endingPage "720" @default.
• W1934701412 startingPage "715" @default.
• W1934701412 abstract "<b><i>Objective:</i></b> The aim of this study was to evaluate cytokeratin-18M65 (CK-18M65) for distinguishing between simple steatosis (SS) and non-alcoholic steatohepatitis (NASH) against healthy individuals (HIs) in Japanese population. <b><i>Methods:</i></b> The serum from 24 HIs, 21 patients with SS and 20 patients with NASH were examined. Serum CK-18M65 was measured by enzyme-linked immunosorbent assay. <b><i>Results:</i></b> Aspartate aminotransferase was significantly different between NASH patients and HIs with p < 0.0001 (SS patients and HIs: p < 0.0001), as was alanine aminotransferase between NASH patients and HIs with p < 0.0001 (SS patients and HIs: p < 0.0001). Serum CK-18M65 increased in a stepwise fashion in HIs and also in SS and NASH patients. Multivariate logistic regression analysis revealed that NASH could be diagnosed with the use of CK-18M65 alone (p = 0.0285, OR 1.0038, 95% CI 1.0004-1.0073). At the optimal cut-off level of 548 U/l, CK-18M65 had an AUC value of 0.7369, 60.00% sensitivity and 85.70% specificity. In patients with NASH, no significant difference was observed between low fibrosis (Stage 0-1, 794.30 ± 454.41, n = 10) and high fibrosis (Stage 2-3, 809.70 ± 641.43, n = 10; p = 0.5967) and between slight steatosis (<33%, 512.89 ± 229.65, n = 9) and moderate steatosis (≥33%, 655.13 ± 480.78, n = 32) in patients with non-alcoholic fatty liver disease (NAFLD; p = 0.7647) with the use of CK-18M65. <b><i>Conclusion:</i></b> Serum CK-18M65 distinguished NASH from SS, but could not assess the severity of steatosis in NAFLD patients or the grade of fibrosis in NASH patients in Japanese population." @default.
• W1934701412 created "2016-06-24" @default.
• W1934701412 creator A5010907477 @default.
• W1934701412 creator A5011867024 @default.
• W1934701412 creator A5014679658 @default.
• W1934701412 creator A5016167810 @default.
• W1934701412 creator A5026634426 @default.
• W1934701412 creator A5032900701 @default.
• W1934701412 creator A5040092260 @default.
• W1934701412 creator A5040210619 @default.
• W1934701412 creator A5061168021 @default.
• W1934701412 creator A5062603464 @default.
• W1934701412 creator A5067984107 @default.
• W1934701412 creator A5071307274 @default.
• W1934701412 date "2015-01-01" @default.
• W1934701412 modified "2023-09-25" @default.
• W1934701412 title "Usefulness of Cytokeratin-18M65 in Diagnosing Non-Alcoholic Steatohepatitis in Japanese Population" @default.
• W1934701412 cites W1963577430 @default.
• W1934701412 cites W1963683487 @default.
• W1934701412 cites W1964108702 @default.
• W1934701412 cites W1969295126 @default.
• W1934701412 cites W1977533715 @default.
• W1934701412 cites W1983181715 @default.
• W1934701412 cites W1986639152 @default.
• W1934701412 cites W1992204676 @default.
• W1934701412 cites W2006588567 @default.
• W1934701412 cites W2007781328 @default.
• W1934701412 cites W2016617561 @default.
• W1934701412 cites W2023075325 @default.
• W1934701412 cites W2027287968 @default.
• W1934701412 cites W2047257800 @default.
• W1934701412 cites W2054488840 @default.
• W1934701412 cites W2057320475 @default.
• W1934701412 cites W2059220708 @default.
• W1934701412 cites W2060847352 @default.
• W1934701412 cites W2065974239 @default.
• W1934701412 cites W2067740038 @default.
• W1934701412 cites W2068980784 @default.
• W1934701412 cites W2074203821 @default.
• W1934701412 cites W2074594336 @default.
• W1934701412 cites W2079558158 @default.
• W1934701412 cites W2080342985 @default.
• W1934701412 cites W2121598176 @default.
• W1934701412 cites W2142026804 @default.
• W1934701412 cites W2153997209 @default.
• W1934701412 cites W2163803773 @default.
• W1934701412 doi "https://doi.org/10.1159/000439076" @default.
• W1934701412 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26488474" @default.
• W1934701412 hasPublicationYear "2015" @default.
• W1934701412 type Work @default.
• W1934701412 sameAs 1934701412 @default.
• W1934701412 citedByCount "8" @default.
• W1934701412 countsByYear W19347014122015 @default.
• W1934701412 countsByYear W19347014122016 @default.
• W1934701412 countsByYear W19347014122017 @default.
• W1934701412 countsByYear W19347014122020 @default.
• W1934701412 crossrefType "journal-article" @default.
• W1934701412 hasAuthorship W1934701412A5010907477 @default.
• W1934701412 hasAuthorship W1934701412A5011867024 @default.
• W1934701412 hasAuthorship W1934701412A5014679658 @default.
• W1934701412 hasAuthorship W1934701412A5016167810 @default.
• W1934701412 hasAuthorship W1934701412A5026634426 @default.
• W1934701412 hasAuthorship W1934701412A5032900701 @default.
• W1934701412 hasAuthorship W1934701412A5040092260 @default.
• W1934701412 hasAuthorship W1934701412A5040210619 @default.
• W1934701412 hasAuthorship W1934701412A5061168021 @default.
• W1934701412 hasAuthorship W1934701412A5062603464 @default.
• W1934701412 hasAuthorship W1934701412A5067984107 @default.
• W1934701412 hasAuthorship W1934701412A5071307274 @default.
• W1934701412 hasConcept C126322002 @default.
• W1934701412 hasConcept C2776175330 @default.
• W1934701412 hasConcept C2778772119 @default.
• W1934701412 hasConcept C2779134260 @default.
• W1934701412 hasConcept C2779478299 @default.
• W1934701412 hasConcept C2780559512 @default.
• W1934701412 hasConcept C2908647359 @default.
• W1934701412 hasConcept C71924100 @default.
• W1934701412 hasConcept C90924648 @default.
• W1934701412 hasConcept C99454951 @default.
• W1934701412 hasConceptScore W1934701412C126322002 @default.
• W1934701412 hasConceptScore W1934701412C2776175330 @default.
• W1934701412 hasConceptScore W1934701412C2778772119 @default.
• W1934701412 hasConceptScore W1934701412C2779134260 @default.
• W1934701412 hasConceptScore W1934701412C2779478299 @default.
• W1934701412 hasConceptScore W1934701412C2780559512 @default.
• W1934701412 hasConceptScore W1934701412C2908647359 @default.
• W1934701412 hasConceptScore W1934701412C71924100 @default.
• W1934701412 hasConceptScore W1934701412C90924648 @default.
• W1934701412 hasConceptScore W1934701412C99454951 @default.
• W1934701412 hasIssue "6" @default.
• W1934701412 hasLocation W19347014121 @default.
• W1934701412 hasLocation W19347014122 @default.
• W1934701412 hasOpenAccess W1934701412 @default.
• W1934701412 hasPrimaryLocation W19347014121 @default.
• W1934701412 hasRelatedWork W12296056 @default.
• W1934701412 hasRelatedWork W2032327238 @default.
• W1934701412 hasRelatedWork W2036698572 @default.
• W1934701412 hasRelatedWork W2054571656 @default.

• next