FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1935158889> ?p ?o ?g. }

• W1935158889 abstract "Abstract Background Proteins carrying twin-arginine (Tat) signal peptides are exported into the periplasmic compartment or extracellular environment independently of the classical Sec-dependent translocation pathway. To complement other methods for classical signal peptide prediction we here present a publicly available method, TatP, for prediction of bacterial Tat signal peptides. Results We have retrieved sequence data for Tat substrates in order to train a computational method for discrimination of Sec and Tat signal peptides. The TatP method is able to positively classify 91% of 35 known Tat signal peptides and 84% of the annotated cleavage sites of these Tat signal peptides were correctly predicted. This method generates far less false positive predictions on various datasets than using simple pattern matching. Moreover, on the same datasets TatP generates less false positive predictions than a complementary rule based prediction method. Conclusion The method developed here is able to discriminate Tat signal peptides from cytoplasmic proteins carrying a similar motif, as well as from Sec signal peptides, with high accuracy. The method allows filtering of input sequences based on Perl syntax regular expressions, whereas hydrophobicity discrimination of Tat- and Sec-signal peptides is carried out by an artificial neural network. A potential cleavage site of the predicted Tat signal peptide is also reported. The TatP prediction server is available as a public web server at http://www.cbs.dtu.dk/services/TatP/ ." @default.
• W1935158889 created "2016-06-24" @default.
• W1935158889 creator A5002675555 @default.
• W1935158889 creator A5004813876 @default.
• W1935158889 creator A5040006242 @default.
• W1935158889 creator A5074122105 @default.
• W1935158889 creator A5090196992 @default.
• W1935158889 date "2005-07-02" @default.
• W1935158889 modified "2023-10-09" @default.
• W1935158889 title "Prediction of twin-arginine signal peptides" @default.
• W1935158889 cites W1555428325 @default.
• W1935158889 cites W1974682887 @default.
• W1935158889 cites W1987035427 @default.
• W1935158889 cites W1997701996 @default.
• W1935158889 cites W2005211587 @default.
• W1935158889 cites W2005632350 @default.
• W1935158889 cites W2006175108 @default.
• W1935158889 cites W2012359868 @default.
• W1935158889 cites W2017564780 @default.
• W1935158889 cites W2041877620 @default.
• W1935158889 cites W2042620330 @default.
• W1935158889 cites W2045985595 @default.
• W1935158889 cites W2077640701 @default.
• W1935158889 cites W2097634886 @default.
• W1935158889 cites W2104828227 @default.
• W1935158889 cites W2105986552 @default.
• W1935158889 cites W2116683408 @default.
• W1935158889 cites W2123838632 @default.
• W1935158889 cites W2133542385 @default.
• W1935158889 cites W2143599839 @default.
• W1935158889 cites W2145066558 @default.
• W1935158889 cites W2146626338 @default.
• W1935158889 cites W2148622452 @default.
• W1935158889 cites W2153134143 @default.
• W1935158889 cites W2159052590 @default.
• W1935158889 cites W2161746138 @default.
• W1935158889 cites W2171091522 @default.
• W1935158889 cites W2289232069 @default.
• W1935158889 cites W4213149192 @default.
• W1935158889 doi "https://doi.org/10.1186/1471-2105-6-167" @default.
• W1935158889 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1182353" @default.
• W1935158889 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15992409" @default.
• W1935158889 hasPublicationYear "2005" @default.
• W1935158889 type Work @default.
• W1935158889 sameAs 1935158889 @default.
• W1935158889 citedByCount "466" @default.
• W1935158889 countsByYear W19351588892012 @default.
• W1935158889 countsByYear W19351588892013 @default.
• W1935158889 countsByYear W19351588892014 @default.
• W1935158889 countsByYear W19351588892015 @default.
• W1935158889 countsByYear W19351588892016 @default.
• W1935158889 countsByYear W19351588892017 @default.
• W1935158889 countsByYear W19351588892018 @default.
• W1935158889 countsByYear W19351588892019 @default.
• W1935158889 countsByYear W19351588892020 @default.
• W1935158889 countsByYear W19351588892021 @default.
• W1935158889 countsByYear W19351588892022 @default.
• W1935158889 countsByYear W19351588892023 @default.
• W1935158889 crossrefType "journal-article" @default.
• W1935158889 hasAuthorship W1935158889A5002675555 @default.
• W1935158889 hasAuthorship W1935158889A5004813876 @default.
• W1935158889 hasAuthorship W1935158889A5040006242 @default.
• W1935158889 hasAuthorship W1935158889A5074122105 @default.
• W1935158889 hasAuthorship W1935158889A5090196992 @default.
• W1935158889 hasBestOaLocation W19351588891 @default.
• W1935158889 hasConcept C104317684 @default.
• W1935158889 hasConcept C10858879 @default.
• W1935158889 hasConcept C151730666 @default.
• W1935158889 hasConcept C153180895 @default.
• W1935158889 hasConcept C154945302 @default.
• W1935158889 hasConcept C167625842 @default.
• W1935158889 hasConcept C175156509 @default.
• W1935158889 hasConcept C199360897 @default.
• W1935158889 hasConcept C2777468819 @default.
• W1935158889 hasConcept C2779281246 @default.
• W1935158889 hasConcept C2779843651 @default.
• W1935158889 hasConcept C2908929163 @default.
• W1935158889 hasConcept C41008148 @default.
• W1935158889 hasConcept C43369102 @default.
• W1935158889 hasConcept C515207424 @default.
• W1935158889 hasConcept C55493867 @default.
• W1935158889 hasConcept C70721500 @default.
• W1935158889 hasConcept C86803240 @default.
• W1935158889 hasConceptScore W1935158889C104317684 @default.
• W1935158889 hasConceptScore W1935158889C10858879 @default.
• W1935158889 hasConceptScore W1935158889C151730666 @default.
• W1935158889 hasConceptScore W1935158889C153180895 @default.
• W1935158889 hasConceptScore W1935158889C154945302 @default.
• W1935158889 hasConceptScore W1935158889C167625842 @default.
• W1935158889 hasConceptScore W1935158889C175156509 @default.
• W1935158889 hasConceptScore W1935158889C199360897 @default.
• W1935158889 hasConceptScore W1935158889C2777468819 @default.
• W1935158889 hasConceptScore W1935158889C2779281246 @default.
• W1935158889 hasConceptScore W1935158889C2779843651 @default.
• W1935158889 hasConceptScore W1935158889C2908929163 @default.
• W1935158889 hasConceptScore W1935158889C41008148 @default.
• W1935158889 hasConceptScore W1935158889C43369102 @default.
• W1935158889 hasConceptScore W1935158889C515207424 @default.
• W1935158889 hasConceptScore W1935158889C55493867 @default.
• W1935158889 hasConceptScore W1935158889C70721500 @default.

• next