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- W1935585954 abstract "Summary Human autoimmune diseases, such as multiple sclerosis, type 1 diabetes, rheumatoid arthritis and systemic lupus erythematosus (SLE), are linked genetically to distinct major histocompatibility complex (MHC) class II molecules and other immune modulators. However, genetic predisposition is only one risk factor for the development of these diseases, and low concordance rates in monozygotic twins as well as geographical distribution of disease risk suggest a critical role for environmental factors in the triggering of these autoimmune diseases. Among potential environmental factors, infections have been implicated in the onset and/or promotion of autoimmunity. This review will discuss human autoimmune diseases with a potential viral cause, and outline potential mechanisms by which pathogens can trigger autoimmune disease as discerned from various animal models of infection-induced autoimmune disease." @default.
- W1935585954 created "2016-06-24" @default.
- W1935585954 creator A5033876610 @default.
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- W1935585954 date "2010-03-11" @default.
- W1935585954 modified "2023-10-10" @default.
- W1935585954 title "99th Dahlem Conference on Infection, Inflammation and Chronic Inflammatory Disorders: Triggering of autoimmune diseases by infections" @default.
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- W1935585954 doi "https://doi.org/10.1111/j.1365-2249.2010.04132.x" @default.
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