Matches in SemOpenAlex for { <https://semopenalex.org/work/W1936004857> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W1936004857 endingPage "2207" @default.
- W1936004857 startingPage "2202" @default.
- W1936004857 abstract "Abstract Human PBL cells, sensitized in vitro to TNP or FITC-modified autologous stimulators, have been successfully grown in long-term culture by using TCGF derived from PHA-activated tonsil cells. Long-term cultures consist almost exclusively of T lymphocytes as defined by the formation of spontaneous rosettes with sheep erythrocytes and C-mediated lysis with heteroantibodies to human T cells (R alpha T H). The majority, but not all of these T cells, bear surface Ia antigens as detected by C-mediated lysis in the presence of alpha p23,30. Functionally, these cultures maintain high levels of hapten-specific cytolytic activity during many weeks of culture. In addition, a number of these T cell lines exhibit hapten specific proliferation when co-cultured with x-irradiated hapten modified autologous cells. During this proliferative response, helper factor(s) are released that trigger B cell differentiation into AFC. Data are presented that demonstrate that helper factor(s) production by T cell line cells is preferentially triggered by autologous, but nt allogeneic stimulator cells, bearing the relevant hapten." @default.
- W1936004857 created "2016-06-24" @default.
- W1936004857 creator A5003995610 @default.
- W1936004857 creator A5045638230 @default.
- W1936004857 creator A5074257128 @default.
- W1936004857 creator A5086590991 @default.
- W1936004857 date "1980-11-01" @default.
- W1936004857 modified "2023-10-10" @default.
- W1936004857 title "Hapten-specific human T cell lines. I. Functional analysis with respect to cytotoxic and helper activity." @default.
- W1936004857 doi "https://doi.org/10.4049/jimmunol.125.5.2202" @default.
- W1936004857 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6968775" @default.
- W1936004857 hasPublicationYear "1980" @default.
- W1936004857 type Work @default.
- W1936004857 sameAs 1936004857 @default.
- W1936004857 citedByCount "9" @default.
- W1936004857 crossrefType "journal-article" @default.
- W1936004857 hasAuthorship W1936004857A5003995610 @default.
- W1936004857 hasAuthorship W1936004857A5045638230 @default.
- W1936004857 hasAuthorship W1936004857A5074257128 @default.
- W1936004857 hasAuthorship W1936004857A5086590991 @default.
- W1936004857 hasBestOaLocation W19360048571 @default.
- W1936004857 hasConcept C147483822 @default.
- W1936004857 hasConcept C153911025 @default.
- W1936004857 hasConcept C154317977 @default.
- W1936004857 hasConcept C202751555 @default.
- W1936004857 hasConcept C203014093 @default.
- W1936004857 hasConcept C2776090121 @default.
- W1936004857 hasConcept C29144244 @default.
- W1936004857 hasConcept C54355233 @default.
- W1936004857 hasConcept C55493867 @default.
- W1936004857 hasConcept C73588182 @default.
- W1936004857 hasConcept C81885089 @default.
- W1936004857 hasConcept C86803240 @default.
- W1936004857 hasConcept C8891405 @default.
- W1936004857 hasConcept C95444343 @default.
- W1936004857 hasConceptScore W1936004857C147483822 @default.
- W1936004857 hasConceptScore W1936004857C153911025 @default.
- W1936004857 hasConceptScore W1936004857C154317977 @default.
- W1936004857 hasConceptScore W1936004857C202751555 @default.
- W1936004857 hasConceptScore W1936004857C203014093 @default.
- W1936004857 hasConceptScore W1936004857C2776090121 @default.
- W1936004857 hasConceptScore W1936004857C29144244 @default.
- W1936004857 hasConceptScore W1936004857C54355233 @default.
- W1936004857 hasConceptScore W1936004857C55493867 @default.
- W1936004857 hasConceptScore W1936004857C73588182 @default.
- W1936004857 hasConceptScore W1936004857C81885089 @default.
- W1936004857 hasConceptScore W1936004857C86803240 @default.
- W1936004857 hasConceptScore W1936004857C8891405 @default.
- W1936004857 hasConceptScore W1936004857C95444343 @default.
- W1936004857 hasIssue "5" @default.
- W1936004857 hasLocation W19360048571 @default.
- W1936004857 hasLocation W19360048572 @default.
- W1936004857 hasOpenAccess W1936004857 @default.
- W1936004857 hasPrimaryLocation W19360048571 @default.
- W1936004857 hasRelatedWork W1541421624 @default.
- W1936004857 hasRelatedWork W1570611950 @default.
- W1936004857 hasRelatedWork W1578491423 @default.
- W1936004857 hasRelatedWork W1964137221 @default.
- W1936004857 hasRelatedWork W2008949385 @default.
- W1936004857 hasRelatedWork W2029644809 @default.
- W1936004857 hasRelatedWork W2053177727 @default.
- W1936004857 hasRelatedWork W2090885582 @default.
- W1936004857 hasRelatedWork W2583744448 @default.
- W1936004857 hasRelatedWork W4313313357 @default.
- W1936004857 hasVolume "125" @default.
- W1936004857 isParatext "false" @default.
- W1936004857 isRetracted "false" @default.
- W1936004857 magId "1936004857" @default.
- W1936004857 workType "article" @default.