Matches in SemOpenAlex for { <https://semopenalex.org/work/W1936032545> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W1936032545 endingPage "71" @default.
- W1936032545 startingPage "66" @default.
- W1936032545 abstract "Abstract The distribution of 14C in the unsaponifiable (neutral) and saponifiable (acidic) components of tissue lipids was examined 4, 24, and 72 hours after the subcutaneous injection of [2-14C]mevalonate into 9-day-old rats. Of the total radioactivity contained in the unsaponifiable plus saponifiable material, 7 to 33% was in the acidic fraction obtained from the brain, spinal cord, and the skin, most of it (90% in the brain and spinal cord) being associated with palmitate and stearate in the ratio of 8:2 or 7:3, 4 hours after the injections. Seventy-two hours after the injections the stearate became slightly more heavily labeled than palmitate in these three organs. The palmitate and stearate from the kidney and lung lipids became labeled also, but not as extensively as in the three organs of ectodermal origin. In contrast the n-fatty acids from liver did not contain detectable isotopic label. The incorporation of label into the two fatty acids in the brain and skin increased linearly with increasing doses of mevalonate. It is postulated that label from [2-14C]mevalonate is diverted through a shunt to 3-hydroxy-3-methyl-glutaryl-CoA and free acetoacetate which is utilized preferentially for fatty acid synthesis in the brain, spinal cord, and the skin. Mechanisms which could account for the recycling of carbon atoms from intermediates of sterol biosynthesis are presented." @default.
- W1936032545 created "2016-06-24" @default.
- W1936032545 creator A5060683596 @default.
- W1936032545 creator A5079291529 @default.
- W1936032545 date "1974-01-01" @default.
- W1936032545 modified "2023-10-11" @default.
- W1936032545 title "Transfer of Carbon Atoms from Mevalonate to n-Fatty Acids" @default.
- W1936032545 cites W1502484522 @default.
- W1936032545 cites W1529887823 @default.
- W1936032545 cites W1555293918 @default.
- W1936032545 cites W1566526251 @default.
- W1936032545 cites W1819324606 @default.
- W1936032545 cites W182285968 @default.
- W1936032545 cites W1827211888 @default.
- W1936032545 cites W1938553409 @default.
- W1936032545 cites W1999405126 @default.
- W1936032545 cites W2035193977 @default.
- W1936032545 cites W2043966314 @default.
- W1936032545 cites W2069769822 @default.
- W1936032545 cites W2089403719 @default.
- W1936032545 cites W2092384898 @default.
- W1936032545 cites W2187042516 @default.
- W1936032545 cites W2407160000 @default.
- W1936032545 cites W289394888 @default.
- W1936032545 doi "https://doi.org/10.1016/s0021-9258(19)43091-3" @default.
- W1936032545 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4809631" @default.
- W1936032545 hasPublicationYear "1974" @default.
- W1936032545 type Work @default.
- W1936032545 sameAs 1936032545 @default.
- W1936032545 citedByCount "150" @default.
- W1936032545 countsByYear W19360325452012 @default.
- W1936032545 countsByYear W19360325452013 @default.
- W1936032545 countsByYear W19360325452014 @default.
- W1936032545 countsByYear W19360325452015 @default.
- W1936032545 countsByYear W19360325452016 @default.
- W1936032545 countsByYear W19360325452018 @default.
- W1936032545 countsByYear W19360325452019 @default.
- W1936032545 countsByYear W19360325452022 @default.
- W1936032545 crossrefType "journal-article" @default.
- W1936032545 hasAuthorship W1936032545A5060683596 @default.
- W1936032545 hasAuthorship W1936032545A5079291529 @default.
- W1936032545 hasBestOaLocation W19360325451 @default.
- W1936032545 hasConcept C104779481 @default.
- W1936032545 hasConcept C140205800 @default.
- W1936032545 hasConcept C159985019 @default.
- W1936032545 hasConcept C185592680 @default.
- W1936032545 hasConcept C192562407 @default.
- W1936032545 hasConcept C55493867 @default.
- W1936032545 hasConceptScore W1936032545C104779481 @default.
- W1936032545 hasConceptScore W1936032545C140205800 @default.
- W1936032545 hasConceptScore W1936032545C159985019 @default.
- W1936032545 hasConceptScore W1936032545C185592680 @default.
- W1936032545 hasConceptScore W1936032545C192562407 @default.
- W1936032545 hasConceptScore W1936032545C55493867 @default.
- W1936032545 hasIssue "1" @default.
- W1936032545 hasLocation W19360325451 @default.
- W1936032545 hasOpenAccess W1936032545 @default.
- W1936032545 hasPrimaryLocation W19360325451 @default.
- W1936032545 hasRelatedWork W1531601525 @default.
- W1936032545 hasRelatedWork W2319480705 @default.
- W1936032545 hasRelatedWork W2384464875 @default.
- W1936032545 hasRelatedWork W2398689458 @default.
- W1936032545 hasRelatedWork W2606230654 @default.
- W1936032545 hasRelatedWork W2607424097 @default.
- W1936032545 hasRelatedWork W2748952813 @default.
- W1936032545 hasRelatedWork W2899084033 @default.
- W1936032545 hasRelatedWork W2948807893 @default.
- W1936032545 hasRelatedWork W2778153218 @default.
- W1936032545 hasVolume "249" @default.
- W1936032545 isParatext "false" @default.
- W1936032545 isRetracted "false" @default.
- W1936032545 magId "1936032545" @default.
- W1936032545 workType "article" @default.