FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1936392772> ?p ?o ?g. }

• W1936392772 abstract "Background: Vitiligo is an acquired disease in which the loss of functional melanocytes results in depigmented macules and patches. Over the years, wide arrays of markers for melanocytes have been described, including human melanoma black 45 (HMB-45). Narrow-band ultraviolet B (NB-UVB) therapy is one of the therapeutic modalities for vitiligo. Objectives: We sought to detect HMB-45 staining after 30 sessions of NB-UVB therapy in vitiligo and perivitiliginous skin. Patients and Methods: All the participants were planned to have 30 sessions of NB-UVB therapy with 724 lamps (FS, 72 T, 12-HO Daavlin MED) at 311 nm wavelengths. The patients underwent skin sampling from lesional and perilesional area before and after 30 sessions of treatment. The skin biopsies were sent to the laboratory for light microscopy and immunohistochemical study. The evaluation of HMB-45 was based on the quantitative method, measuring the number of positive stained cells. Clinical response was defined as repigmentation in three categories: more than 75%; between 40% and 75%; and less than 40%. The data were analyzed using SPSS (version 17). Results: Twenty-nine patients completed the study. The Wilcoxon test showed a meaningful relation between HMB-45 staining before and after NB-UVB treatment in perilesional skin. We did not find a meaningful relation between HMB-45 staining before and after treatment regarding the mean age, gender, mean duration of disease, and initial lesional area (P = 0.55, P = 0.41, P = 0.55, and P = 0.87, respectively). After 30 sessions of NB-UVB therapy, repigmentation was less than 40% in 8 (27.6%), 40 - 75% in 7 (24.1%), and more than 75% in 6 patients. Conclusions: The HMB-45 stain strength significantly changed after treatment in perilesional skin." @default.
• W1936392772 created "2016-06-24" @default.
• W1936392772 creator A5007316431 @default.
• W1936392772 creator A5018947527 @default.
• W1936392772 creator A5083606793 @default.
• W1936392772 date "2015-06-27" @default.
• W1936392772 modified "2023-09-26" @default.
• W1936392772 title "HMB-45 Study before and after Narrow-Band (311 nm) Ultraviolet B Treatment in Vitiligo" @default.
• W1936392772 cites W1480019239 @default.
• W1936392772 cites W1767128995 @default.
• W1936392772 cites W1968789733 @default.
• W1936392772 cites W2061965873 @default.
• W1936392772 cites W2081119741 @default.
• W1936392772 cites W2090467962 @default.
• W1936392772 cites W2100208895 @default.
• W1936392772 cites W2148026257 @default.
• W1936392772 cites W4211161884 @default.
• W1936392772 doi "https://doi.org/10.5812/jjhr.28712v2" @default.
• W1936392772 hasPublicationYear "2015" @default.
• W1936392772 type Work @default.
• W1936392772 sameAs 1936392772 @default.
• W1936392772 citedByCount "0" @default.
• W1936392772 crossrefType "journal-article" @default.
• W1936392772 hasAuthorship W1936392772A5007316431 @default.
• W1936392772 hasAuthorship W1936392772A5018947527 @default.
• W1936392772 hasAuthorship W1936392772A5083606793 @default.
• W1936392772 hasBestOaLocation W19363927721 @default.
• W1936392772 hasConcept C142724271 @default.
• W1936392772 hasConcept C16005928 @default.
• W1936392772 hasConcept C2779980618 @default.
• W1936392772 hasConcept C2780564577 @default.
• W1936392772 hasConcept C2910796831 @default.
• W1936392772 hasConcept C3018555722 @default.
• W1936392772 hasConcept C71924100 @default.
• W1936392772 hasConcept C74864618 @default.
• W1936392772 hasConceptScore W1936392772C142724271 @default.
• W1936392772 hasConceptScore W1936392772C16005928 @default.
• W1936392772 hasConceptScore W1936392772C2779980618 @default.
• W1936392772 hasConceptScore W1936392772C2780564577 @default.
• W1936392772 hasConceptScore W1936392772C2910796831 @default.
• W1936392772 hasConceptScore W1936392772C3018555722 @default.
• W1936392772 hasConceptScore W1936392772C71924100 @default.
• W1936392772 hasConceptScore W1936392772C74864618 @default.
• W1936392772 hasIssue "3" @default.
• W1936392772 hasLocation W19363927721 @default.
• W1936392772 hasOpenAccess W1936392772 @default.
• W1936392772 hasPrimaryLocation W19363927721 @default.
• W1936392772 hasRelatedWork W1983550826 @default.
• W1936392772 hasRelatedWork W2170406937 @default.
• W1936392772 hasRelatedWork W2353101942 @default.
• W1936392772 hasRelatedWork W2366993061 @default.
• W1936392772 hasRelatedWork W2369215589 @default.
• W1936392772 hasRelatedWork W2379891004 @default.
• W1936392772 hasRelatedWork W3031435291 @default.
• W1936392772 hasRelatedWork W3193412786 @default.
• W1936392772 hasRelatedWork W4247807021 @default.
• W1936392772 hasRelatedWork W4313451094 @default.
• W1936392772 hasVolume "6" @default.
• W1936392772 isParatext "false" @default.
• W1936392772 isRetracted "false" @default.
• W1936392772 magId "1936392772" @default.
• W1936392772 workType "article" @default.