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- W1937228367 abstract "In soma and germ cells of Drosophila, the X:A ratio builds a primary signal for sex determination, and in both tissues Sex-lethal (Sxl) function is required for cells to enter the female pathway. In somatic cells of XX animals, the products of X-chromosomal elements of the X:A ratio activate Sxl. Here I show that sisterless-b (sis-b), which is the X-chromosomal element of the somatic X:A ratio that has best been analysed, is not required for oogenesis. I also present evidence that Sxl function might not be sufficient to direct germ cells into the female pathway. These results show that the elements forming the X:A ratio in the germ line are different from the elements forming the X:A ratio in the soma and they suggest that, in the germ line, Sxl might not be regulated by the X:A ratio." @default.
- W1937228367 created "2016-06-24" @default.
- W1937228367 creator A5083674098 @default.
- W1937228367 date "1993-02-01" @default.
- W1937228367 modified "2023-09-23" @default.
- W1937228367 title "Sex determination in <i>Drosophila</i>: <i>sis-b</i>, a major numerator element of the X:A ratio in the soma, does not contribute to the X:A ratio in the germ line" @default.
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- W1937228367 doi "https://doi.org/10.1242/dev.117.2.763" @default.
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